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Full Time Director Clinical Operations Jobs (NOW HIRING)

Ascension

Director Clinical Operations

Flint, MI

$92K/yr

Clinical Operations Schedule: Full-time | Day Salary range: $92,493.52 - $125,138.10 per year Life ... Direct and optimize departmental operations to deliver high-quality, cost-effective care. Provide ...

Alira Health

Summary The Senior Director, Clinical Operations, is a key member of the Executive Leadership Team responsible for the strategic and operational leadership of the Company's clinical development ...

AMSURG

Director, Clinical Operations - Northeast Remote Company Overview: AMSURG is an independent leader in ambulatory surgery center services, operating a network of more than 250 surgery centers ...

AMSURG

Director, Clinical Operations - Northeast

Director, Clinical Operations - Northeast Remote Company Overview: AMSURG is an independent leader in ambulatory surgery center services, operating a network of more than 250 surgery centers ...

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Full Time Director Clinical Operations information

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How much do full time director clinical operations jobs pay per year?

As of Aug 14, 2026, the average yearly pay for full time director clinical operations in the United States is $145,969.00, according to ZipRecruiter salary data. Most workers in this role earn between $102,000.00 and $173,500.00 per year, depending on experience, location, and employer.

What is the difference between Full Time Director Clinical Operations vs Clinical Project Manager?

AspectFull Time Director Clinical OperationsClinical Project Manager
CredentialsAdvanced degrees (e.g., MD, PhD, or related), extensive industry experienceBachelor's or Master's degree in life sciences or related field, relevant project management certifications
Work EnvironmentOversees multiple projects, manages teams, strategic planningManages individual clinical trials, coordinates project activities
Employer & Industry UsagePharmaceutical, biotech companies, CROsPharmaceutical, biotech companies, CROs

The Full Time Director Clinical Operations focuses on strategic oversight and leadership of clinical operations across multiple projects, requiring higher-level credentials and experience. In contrast, the Clinical Project Manager handles the day-to-day management of specific clinical trials, with a more tactical role. Both roles are essential in the clinical research industry but differ in scope and responsibilities.

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Full Time Director Clinical Operations jobs near you
Infographic showing various Full Time Director Clinical Operations job openings in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 90% In-person, and 10% Remote job distribution, with an average salary of $145,969 per year, or $70.2 per hour.

Associate Director, Clinical Operations

Clinical Dynamix, Inc.

Watertown, MA • On-site

Full-time

Re-posted 3 days ago

Job description

Associate Director, Clinical Operations Job Description

How you’ll make an impact:

  • Contribute to the planning, implementation, and execution of global clinical trials.
  • Plan, execute, and lead study-specific meetings (e.g., internal core team meetings, investigator meetings, etc), as needed.
  • Provide input for the design of the Informed Consent Form(s), eCRFs, monitoring conventions, edit checks, etc.
  • Provide study-specific training and leadership to clinical research staff, CRO, CRAs, sites and other contract personnel.
  • Manage study timelines and metrics to ensure completion of study deliverables.
  • Lead site feasibility and selection qualification, initiation, and oversight of outsourced monitoring activities.
  • Review monitoring reports to ensure quality and resolution of site-related issues.
  • Ensure timely enrollment and data collection at clinical trial sites.
  • Collaborate with the data management team to ensure data integrity and timely database lock.
  • Ensure tracking, review of protocol deviations, and assess impact on study data.
  • Work closely with translational medicine team to ensure appropriate incorporation of bioanalytical sampling plan into clinical protocols and relevant data output of the trial is provided to functional groups for review.
  • Partner with Operational Excellence and assigned Site Engagement Leads to help drive site engagement and bolster recruitment
  • Serve as key counterpart of Clinical Outsourcing to build RFPs and support the selection of clinical vendors
  • Oversee and contribute to Sponsor Oversight activities including but not limited to review of KPIs, KRIs, PDs, risks, Data Review Findings, etc. to assess the health of the study and proactively ensure mitigations are in place to achieve Company’s quality standards
  • Contribute to clinical operations process improvement initiatives
  • Maintain accurate and complete trial documentation.
  • Proactively identify and resolve clinical project issues.
  • This role may require up to 25% travel

Skills and experience you’ll bring:

  • BS degree and 8+ years of experience in clinical operations in biotech/pharma. 5 years’ experience leading global clinical trials
  • Inspection readiness experience preferred
  • Experience working on large, global, complex phase 2b/3 or late stage trials. Respiratory or Immunology experience highly preferred.
  • Broad knowledge of Global regulations and guidelines including CFR, ICH GCP, HIPAA, GDPR, and the Protection of Human Research Subjects.
  • Strong project management skills with the ability to manage multiple trials simultaneously.
  • Excellent problem-solving, leadership, and communication skills.
  • Ability to work in a fast-paced, dynamic environment with cross-functional teams.