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Clinical Operations Leader Jobs (NOW HIRING)

Clinovo

Dir, Clinical Operations

Cambridge, MA · On-site

This role requires a leader who operates both strategically and tactically-developing scalable ... Drive clinical operations strategy and execution for an autoimmune/immunology-focused clinical ...

Alopex

Clinical Operations Director

Las Vegas, NV · On-site +1

$135K - $155K/yr

This role serves as the operational leader for day-to-day Clinical Operations and Enrollment execution and partners closely with executive leadership, QA, Product, BI, Technology, and Operations ...

Philips

Director of Clinical Operations

Plymouth, MN · On-site

This role partners with executive leadership and cross-functional teams across IT, Clinical/Medical ... Lead the operational planning and execution of clinical trials and evidence generation programs ...

Philips

Director of Clinical Operations

Bothell, WA

This role partners with executive leadership and cross-functional teams across IT, Clinical/Medical ... Lead the operational planning and execution of clinical trials and evidence generation programs ...

Philips

Director of Clinical Operations

Plymouth, MN · On-site

This role partners with executive leadership and cross-functional teams across IT, Clinical/Medical ... Lead the operational planning and execution of clinical trials and evidence generation programs ...

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Clinical Operations Leader information

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$35K

$98K

$186.5K

How much do clinical operations leader jobs pay per year?

As of Jul 23, 2026, the average yearly pay for clinical operations leader in the United States is $98,039.00, according to ZipRecruiter salary data. Most workers in this role earn between $72,500.00 and $113,500.00 per year, depending on experience, location, and employer.

What is the difference between Clinical Operations Leader vs Clinical Project Manager?

AspectClinical Operations LeaderClinical Project Manager
CredentialsTypically requires a Bachelor's or Master's in life sciences, with experience in clinical operationsRequires similar degrees, often with project management certifications like PMP
Work EnvironmentOversees multiple projects and teams within clinical operations departmentsManages individual clinical trials or projects, coordinating teams and timelines
Employer & Industry UsageUsed in pharmaceutical, biotech, and medical device companies for senior operational rolesCommon in the same industries, focusing on specific clinical studies

The Clinical Operations Leader focuses on overseeing overall clinical operations and strategic planning, while the Clinical Project Manager manages specific clinical trials and project execution. Both roles require similar credentials and are integral to clinical research, but differ in scope and level of responsibility.

What does a Clinical Operations Leader do?

A Clinical Operations Leader is responsible for overseeing the planning, execution, and management of clinical trials within pharmaceutical, biotechnology, or medical device companies. They ensure that studies are conducted in compliance with regulatory requirements, company policies, and good clinical practice guidelines. Their role often involves coordinating cross-functional teams, managing budgets and timelines, and serving as the main point of contact for study sponsors and stakeholders. Clinical Operations Leaders play a key role in ensuring the successful delivery of high-quality clinical research projects.

What are the key skills and qualifications needed to thrive as a Clinical Operations Leader, and why are they important?

To thrive as a Clinical Operations Leader, you need expertise in clinical research management, regulatory compliance, and project leadership, usually backed by a degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), Good Clinical Practice (GCP) guidelines, and relevant certifications such as ACRP or SOCRA is typically required. Exceptional organizational, communication, and problem-solving skills help you navigate complex projects and foster collaboration among cross-functional teams. These capabilities ensure efficient clinical trial execution, regulatory adherence, and the successful delivery of high-quality research outcomes.

What are some common challenges Clinical Operations Leaders face when managing multi-site clinical trials?

Clinical Operations Leaders often encounter challenges such as ensuring consistent protocol adherence across multiple sites, coordinating communication among cross-functional teams, and managing tight timelines while maintaining regulatory compliance. They must also address site-specific issues like varying patient recruitment rates or local regulatory requirements. Successfully navigating these challenges requires strong organizational, communication, and problem-solving skills, as well as the ability to adapt quickly to changing trial dynamics.
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Clinical Operations Leader jobs near you
Infographic showing various Clinical Operations Leader job openings in the United States as of July 2026, with employment types broken down into 2% As Needed, 73% Full Time, 17% Part Time, and 8% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $98,039 per year, or $47.1 per hour.
Global Clinical Operations Leader / Clinical Trial Manager

Global Clinical Operations Leader / Clinical Trial Manager

Parexel

Durham, NC • On-site

Full-time

This job post has expired today. Applications are no longer accepted.

Parexel rating

8.2

Company rating: 8.2 out of 10

Based on 13 frontline employees who took The Breakroom Quiz

24th of 60 rated research

Job description

About Parexel
Parexel is a leading global clinical development partner delivering insights driven clinical and consulting solutions to the life sciences industry. With more than 22,000 employees worldwide, we partner with biopharmaceutical companies and research sites to design and deliver patient focused clinical trials that broaden access and make research a care option for anyone anywhere.
We work with focus agility and shared purpose moving with urgency to address patient needs and accelerate the delivery of new therapies. We embrace bold thinking, adapt quickly to change and continually raise the bar for the speed and quality of clinical research. We are expanding our team and seeking experienced leaders who are motivated by accountability ownership and measurable impact.
About the Role
We are seeking a Global Clinical Operations Leader/Clinical Trial Manager to join our team in a remote position. As a Global Clinical Operations Leader/ Clinical Trial Manager, you will lead the clinical operations strategy and execution of global clinical trials. This role has direct accountability for delivering studies on time within budget and to the highest quality standards while ensuring patient safety and regulatory compliance.
You will serve as the primary clinical liaison to project leadership and sponsor teams coordinating cross functional contributors across regions and time zones. This is a highly visible leadership role suited for individuals who thrive in complex global environments and are comfortable making decisions in ambiguous situations. Success requires strong ownership, the ability to lead without close supervision and a history of delivering clinical trials within a CRO environment.
Key Responsibilities
  • Lead global clinical operations strategy and execution for assigned clinical trials.
  • Drive study startup including site selection, monitoring strategy, and operational planning.
  • Coordinate cross functional teams across geographies ensuring alignment on timelines quality and deliverables.
  • Monitor study progress including recruitment retention data quality and timelines and take corrective action when needed.
  • Identify risks early and implement mitigation and contingency plans.
  • Provide leadership direction and performance feedback to project team members.
  • Function as primary point of contact for sponsors on clinical operations topics.
  • Ensure compliance with ICH GCP regulatory requirements and internal processes.
  • Oversee maintenance and quality of study documentation and central files.
  • Support audits inspections and study closeout activities including database lock and archiving.
  • Provide strategic oversight of the integrated data delivery (IDD) framework and champion a proactive data-quality culture

You will thrive in this role if you bring:
  • Strong leadership decision making and problem-solving skills
  • Demonstrated ability to lead global teams across cultures and time zones
  • Ability to prioritize competing demands and remain accountable for outcomes
  • A proactive mindset with strong ownership and sense of urgency
  • Excellent communication and stakeholder management skills
  • Comfort working in a fast-paced performance driven environment

Required Qualifications
  • Degree in life sciences, nursing, or equivalent clinical research experience
  • Minimum of 5 years of experience leading clinical operations within a CRO environment
  • Proven experience in roles such as Clinical Trial Manager, Clinical Project Manager or Clinical Operations Leader
  • Experience leading complex global or multi-region studies
  • Strong knowledge of ICH GCP regulatory requirements and clinical trial processes
  • Experience coordinating cross functional teams and managing study timelines budgets and quality
  • Proficiency with clinical systems and standard tools such as CTMS, EDC, and eTMF

Preferred Qualifications
  • Prior monitoring experience or strong site engagement background
  • Experience contributing to process improvements or operational excellence initiatives
  • Familiarity with multiple therapeutic areas or late phase studies with priority given to those with Metabolic, Obesity, MASH, Ophthalmology and Dermatology / Immunology

The potential base pay range for this role is competitive and aligned to experience level location and demonstrated expertise. Additional incentives may be available based on performance and role scope.
This role is designed for experienced clinical leaders who are ready to take full ownership of global trial delivery. If you are looking for a position with clear accountability, high expectations and meaningful impact on patient outcomes this is the right opportunity.
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About PAREXEL

Sourced by ZipRecruiter

Bring your Data Management expertise to Parexel's Strategic Partnerships. Although we work globally, each partnership we form is deeply personal. We are as dedicated to every aspect of our client's product development as they are - and work closely with client teams in true partnership to understand both challenges and opportunities. At Parexel we are focused on meeting customer and patient needs through collaborative partnership so that we get treatments into the hands of patients who need them most.

Industry

Pharmaceutical and medicine manufacturing

Company size

10,000+ Employees

Headquarters location

Waltham, MA, US

Year founded

1983

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