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Clinical Operations Leader Jobs (NOW HIRING)

Alopex

Clinical Operations Director

Las Vegas, NV · On-site +1

$135K - $155K/yr

This role serves as the operational leader for day-to-day Clinical Operations and Enrollment execution and partners closely with executive leadership, QA, Product, BI, Technology, and Operations ...

Howard

$140K - $150K/yr

The Director of Clinical Operations provides strategic and operational leadership for clinical services across multiple departments. This role ensures efficient workflows, compliance with regulatory ...

Grand Mental Health

Clinical Operations Manager

Tulsa, OK · On-site

$60K - $70K/yr

This role works directly under the Clinical Services and Operational leadership to allow licensed clinical staff and supervisors to operate at the top of licensure by reducing operational and ...

Monument Dental

Operations Leader

Millbrook, AL · On-site

$50K - $60K/yr

Operations Leader Reports to: Director of Market Operations (DMO) / Regional Manager (RM) FLSA ... Manage ALL nonclinical team members in office and ALL areas/departments of the office * Meet the ...

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Clinical Operations Leader information

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$35K

$98K

$186.5K

How much do clinical operations leader jobs pay per year?

As of Jun 27, 2026, the average yearly pay for clinical operations leader in the United States is $98,039.00, according to ZipRecruiter salary data. Most workers in this role earn between $72,500.00 and $113,500.00 per year, depending on experience, location, and employer.

What does a clinical operations lead do?

A clinical operations lead oversees the planning, execution, and management of clinical trials to ensure they are completed on time, within budget, and in compliance with regulatory standards. They coordinate between teams such as research, regulatory, and data management, often utilizing project management tools and requiring knowledge of Good Clinical Practice (GCP) guidelines.

What is the difference between Clinical Operations Leader vs Clinical Project Manager?

AspectClinical Operations LeaderClinical Project Manager
CredentialsTypically requires a Bachelor's or Master's in life sciences, with experience in clinical operationsRequires similar degrees, often with project management certifications like PMP
Work EnvironmentOversees multiple projects and teams within clinical operations departmentsManages individual clinical trials or projects, coordinating teams and timelines
Employer & Industry UsageUsed in pharmaceutical, biotech, and medical device companies for senior operational rolesCommon in the same industries, focusing on specific clinical studies

The Clinical Operations Leader focuses on overseeing overall clinical operations and strategic planning, while the Clinical Project Manager manages specific clinical trials and project execution. Both roles require similar credentials and are integral to clinical research, but differ in scope and level of responsibility.

What jobs pay 500,000 a year in the US?

In the US, high-level executive roles such as CEOs, CFOs, and other C-suite positions often have annual compensation exceeding $500,000, especially in large corporations. Senior professionals like specialized surgeons, investment bankers, and successful entrepreneurs can also reach or surpass this income level, often through bonuses, stock options, or profit sharing. For a Clinical Operations Leader, reaching this salary typically requires extensive experience, leadership in large organizations, and often additional incentives or equity participation.

What does a Clinical Operations Leader do?

A Clinical Operations Leader is responsible for overseeing the planning, execution, and management of clinical trials within pharmaceutical, biotechnology, or medical device companies. They ensure that studies are conducted in compliance with regulatory requirements, company policies, and good clinical practice guidelines. Their role often involves coordinating cross-functional teams, managing budgets and timelines, and serving as the main point of contact for study sponsors and stakeholders. Clinical Operations Leaders play a key role in ensuring the successful delivery of high-quality clinical research projects.

What are the key skills and qualifications needed to thrive as a Clinical Operations Leader, and why are they important?

To thrive as a Clinical Operations Leader, you need expertise in clinical research management, regulatory compliance, and project leadership, usually backed by a degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), Good Clinical Practice (GCP) guidelines, and relevant certifications such as ACRP or SOCRA is typically required. Exceptional organizational, communication, and problem-solving skills help you navigate complex projects and foster collaboration among cross-functional teams. These capabilities ensure efficient clinical trial execution, regulatory adherence, and the successful delivery of high-quality research outcomes.

Is CRA an entry level job?

A Clinical Research Associate (CRA) is typically not an entry-level position; it usually requires prior experience in clinical research, healthcare, or related fields. Entry-level roles in clinical operations may include clinical trial assistants or coordinators, with CRAs often needing certifications like ACRP or SOCRA and several years of relevant experience. Advancement to CRA roles generally involves developing skills in monitoring, regulatory compliance, and data management.

What jobs in the US pay $300,000 a year?

In the US, senior roles such as Clinical Operations Leaders, medical directors, pharmaceutical executives, and specialized physicians often earn $300,000 or more annually. These positions typically require extensive experience, advanced degrees, and leadership skills, and may involve managing large teams or budgets in healthcare or biotech industries.

What are some common challenges Clinical Operations Leaders face when managing multi-site clinical trials?

Clinical Operations Leaders often encounter challenges such as ensuring consistent protocol adherence across multiple sites, coordinating communication among cross-functional teams, and managing tight timelines while maintaining regulatory compliance. They must also address site-specific issues like varying patient recruitment rates or local regulatory requirements. Successfully navigating these challenges requires strong organizational, communication, and problem-solving skills, as well as the ability to adapt quickly to changing trial dynamics.
More about Clinical Operations Leader jobs
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Clinical Operations Leader jobs near you
Infographic showing various Clinical Operations Leader job openings in the United States as of June 2026, with employment types broken down into 97% Full Time, and 3% Contract. Highlights an 80% In-person, 10% Hybrid, and 10% Remote job distribution, with an average salary of $98,039 per year, or $47.1 per hour.

Clinical Operations Director

Alopex

Las Vegas, NV • On-site, Remote

$135K - $155K/yr

Full-time

Posted 23 days ago

Job description

Job Title: Clinical Operations Director
Overview
The Clinical Operations Director is responsible for leading frontline operational execution across Alopex's Care Coordination and Enrollment teams while driving workforce performance, operational accountability, clinical quality, and scalable operational delivery.
This role serves as the operational leader for day-to-day Clinical Operations and Enrollment execution and partners closely with executive leadership, QA, Product, BI, Technology, and Operations Enablement teams to support organizational growth and operational excellence.
The Clinical Operations Director oversees operational workflows across multiple service lines, including traditional CCM, LTC-focused care coordination, transitional CCM models, and future population health initiatives.
This role owns frontline operational execution, workforce leadership, service line performance, and day-to-day operational accountability across Clinical Operations and Enrollment. While the Operations Enablement & Systems Director owns systems infrastructure, workflow enablement, and operational scalability initiatives, the Clinical Operations Director is responsible for frontline execution, workforce performance, and operational delivery.
This role is instrumental in supporting organizational growth, operational stability, workforce development, and service line scalability during periods of rapid growth and transformation.
Key Responsibilities
Clinical Operations Leadership
  • Provide operational leadership and oversight for Care Coordination and Enrollment teams
  • Directly manage frontline operational staff, including Team Leads, Care Coordinators, and Enrollment Specialists
  • Own frontline operational execution, workforce accountability, and service line performance across Clinical Operations
  • Partner with executive leadership to support organisational growth initiatives and operational scaling
  • Monitor and drive operational KPIs related to productivity, engagement, quality, patient outcomes, and operational performance
  • Support staffing strategy, workforce planning, scheduling oversight, and operational resource allocation
  • Ensure operational consistency across service lines, workflows, and customer implementations

Team Leadership & Staff Development
  • Coach, mentor, and support frontline operational leaders and staff
  • Promote accountability, consistency, and operational excellence across teams
  • Support onboarding, performance management, corrective action, and employee development
  • Foster a collaborative, patient-centred, and high-performance operational culture
  • Lead communication efforts during periods of organisational and operational change
  • Support leadership development and operational growth opportunities within frontline teams.

Operational Execution & Service Line Management
  • Drive operational execution across traditional CCM, LTC and future population health service lines
  • Partner with QA leadership to maintain documentation integrity, operational consistency, and CMS readiness
  • Collaborate with Enablement & Systems leadership to support workflow adoption and operational scalability
  • Support implementation and adoption of operational tools, workflows, and technology solutions
  • Identify operational barriers impacting productivity, patient engagement, or workflow execution and implement corrective action plans
  • Support operational planning related to customer onboarding, transitions, and scaling initiatives

Cross-Functional Collaboration
  • Partner with Product, QA, BI, and Technology and Enablement teams to support operational initiatives and workflow improvements
  • Collaborate with provider groups and customer stakeholders as needed
  • Support implementation of operational reporting, workforce metrics, and operational performance initiatives

Qualifications
  • Active RN license strongly preferred
  • 7+ years of healthcare operations leadership experience
  • Demonstrated experience leading frontline operational teams in healthcare environments
  • Experience in CCM, population health, managed care, telephonic care management, LTC, or value-based care strongly preferred
  • Demonstrated experience leading remote or hybrid operational teams
  • Strong understanding of productivity management, operational KPIs, and workforce planning
  • Experience leading teams through organizational growth, operational change, and workflow transformation
  • Strong communication, coaching, accountability, and leadership skills
  • Comfortable working in a fast-paced, evolving operational environment

Preferred Qualifications
  • Experience supporting healthcare technology implementations or operational transformation initiatives
  • Experience in multi-client healthcare operations environments
  • CCM certification or population health experience preferred
  • Familiarity with CMS documentation and compliance expectations preferred

Key Competencies:
Competency
Definition
Operational leadership
Ability to lead and support enrollment and clinical operations while driving operational consistency, productivity, quality, and scalable growth across teams and service lines.
Team development
Ability to coach, mentor, and develop team members while fostering accountability, engagement, collaboration, and professional growth.
Workforce planning
Ability to assess staffing needs, balance workloads, support resource allocation, and align operational staffing models with patient volumes and organizational goals.
Care Coordination & Population Health Operations Expertise
Strong understanding of care coordination workflows, enrollment operations, productivity management, documentation standards, and operational performance within healthcare environments.
Change management
Ability to lead teams through organizational, operational, and systems changes by promoting clear communication, adoption, stability, and operational continuity.
Accountability & Execution
Ability to drive operational execution, monitor performance, follow through on initiatives, and ensure teams meet operational, quality and organizational expectations.
Communication and collaboration
Ability to communicate effectively across operational, clinical, and cross-functional teams while building strong working relationships and supporting organizational alignment.
Service line management
Ability to oversee operational performance, scalability, and workflow consistency across multiple customer segments and operational programs.
Work Location, Shift & Schedule
This position is fully remote with strict adherence to a Work from Home policy. Occasional travel may be required for client meetings, training sessions, or company meetings. Standard hours are Monday-Friday, 8:00 am-5:00 pm EST, or according to the business hours of clients' practices.
Remote Position Requirements:
  • Reliable high-speed internet connection suitable for professional calls and video conferencing.
  • Quiet, secure, and professional work environment suitable for discussing sensitive health information and Protected Health Information (PHI).

Compensation Range:
$135 - $155K

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