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How much do director statistical programming jobs pay per year?

As of Aug 19, 2026, the average yearly pay for director statistical programming in the United States is $280,147.00, according to ZipRecruiter salary data. Most workers in this role earn between $260,500.00 and $322,500.00 per year, depending on experience, location, and employer.

What is a director statistical programming?

The job of a director of statistical programming oversees the development and implementation of SAS programs to produce statistical analysis datasets. In this career, your responsibilities include managing the team that generates tables and graphs using the SAS programs for applications such as clinical studies. Other duties include participating in the planning and review of statistical analysis and studying reports, abstracts, and manuscripts as required. You collaborate with project leads to contribute to department operations and standards, such as CDISC for clinical research.

What does a director statistical programming do?

A Director of Statistical Programming oversees teams responsible for the programming and analysis of clinical trial data, ensuring the accuracy and integrity of statistical outputs. They set departmental strategies, manage resources, and ensure compliance with regulatory requirements and industry standards. This role also involves collaborating with other departments, such as biostatistics and clinical operations, to support the successful delivery of statistical analyses for drug development and regulatory submissions. They play a key leadership role in mentoring staff and advancing programming processes and technologies.

What are the key skills and qualifications needed to thrive as a director statistical programming?

To thrive as a Director of Statistical Programming, you need advanced expertise in statistical analysis, programming languages such as SAS or R, and a strong background in clinical trial data, typically supported by a degree in statistics, mathematics, or a related field. Familiarity with regulatory submission processes, CDISC standards, and project management tools is essential, as are relevant certifications like SAS Certified Professional. Leadership, effective communication, and strategic thinking are key soft skills for managing teams and collaborating across departments. These skills ensure high-quality data outputs, regulatory compliance, and successful execution of complex clinical development projects.

How does a director statistical programming typically collaborate with cross-functional teams in a pharmaceutical or biotech company?

A Director of Statistical Programming regularly works with biostatistics, clinical data management, regulatory affairs, and medical writing teams to ensure that statistical deliverables meet project timelines and regulatory requirements. They coordinate programming efforts across multiple studies, provide leadership and mentorship to programming staff, and help resolve technical or resource-related challenges. Effective collaboration is essential to streamline workflows, maintain data integrity, and ensure clear communication of statistical results within the organization.
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Director Statistical Programming jobs near you
Infographic showing various Director Statistical Programming job openings in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% Remote job distribution, with an average salary of $280,147 per year, or $134.7 per hour.

Associate Director, Statistical Programming

MBX Biosciences

Burlington, MA

Full-time

Posted yesterday

New

Job description

Working with Us

MBX Biosciences is a clinical-stage biopharmaceutical company headquartered in Carmel, Indiana, with a secondary office in Burlington, MA.  Our mission is to transform the lives of people impacted by endocrine and metabolic disorders through our novel precision peptides.

Leveraging our proprietary Precision Endocrine Peptides (PEPs) platform, we are pioneering technology designed to overcome key limitations of existing therapies and enhance efficacy, tolerability, safety and convenience. Our team is advancing a pipeline of novel candidates with clinically validated targets, established endpoints for regulatory approval, and strong market potential.

Our pipeline includes canvuparatide (MBX 2109) for the treatment of chronic hypoparathyroidism, currently preparing for Phase 3 development, and a growing obesity portfolio that includes MBX 4291 in Phase 1 development, MBX 5765, a next-generation amycretin prodrug designed for once-monthly dosing, as well as MBX 6180, a GLP/GIP/GCGR triple agonist prodrug for once monthly dosing; all of which optimize our PEP platform.

If you're passionate about advancing innovative treatments for patients and shaping the future of precision peptide therapeutics, this is your chance to make a real impact alongside a fast-paced, growing, mission-driven team.  To learn more, visit our website mbxbio.com and follow us on LinkedIn.

Position Summary 

MBX is seeking an Associate Director, Statistical Programming to lead and contribute to  statistical programming and analysis of clinical trial data. This role is integral to the design, execution, and interpretation of analyses for clinical trials and related research activities. The Associate Director will ensure the quality and accuracy of statistical deliverables, oversee external vendor performance, and contribute to internal process improvements, including maintaining and expanding SAS macros, R workflows, and clinical data repositories.

What You'll Do

  • Oversee and execute statistical programming deliverables for planned analyses, including study monitoring, data reviews, clinical study reports, data integrations, and rapid responses to regulatory queries across multiple compounds and studies.
  • Lead global submission activities, acting as a programming functional and technical expert to support submission strategy planning and regulatory communications; ensure all programming deliverables meet timelines, quality standards, and regulatory expectations (eg, ICH, FDA, EMA).
  • Manage CROs and contractors to ensure compliance, high-quality deliverables, adherence to timelines, and budget alignment.
  • Develop and validate reproducible, well-documented statistical programs to produce outputs for integrated scientific reports of clinical trial results, ensuring adherence to protocols and Statistical Analysis Plans (SAPs), and regulatory reporting conventions.
  • Maintain and enhance the internal SAS macro library and database.
  • Provide statistical programming input for SAPs, publications, scientific presentations, regulatory submissions, and promotional materials.
  • Review Case Report Forms (CRFs), CRF annotations, SAPs, Table, Listing, and Figure (TLF) shells, TLF outputs, dataset specifications (SDTM and ADaM).
  • Serve as a lead for statistical programming within study teams, effectively communicating statistical and programming issues to development teams.
  • Contribute to the development of programming standards, macros, SOPs, and process improvements within the Biometrics function
  • Other responsibilities as assigned.

What You Bring

  • 8+ years of statistical programming experience in the biotech or pharmaceutical industry, with a preference for expertise in endocrine and metabolic disorders.
  • Advanced degree (PhD, MS,  etc.) in life sciences, biostatistics, mathematics, computer science, or a related field preferred.
  • Proficient in SAS programming (e.g., Base SAS, SAS/Stat, SAS/Graph, SAS macros, ODS) with a solid understanding of database systems
  • Experience with R and Python preferred for advanced data visualization and analysis.
  • Extensive experience with CDISC standards (SDTM, ADaM, define.xml) and electronic submissions (eSub) under eCTD specifications.
  • Proven ability to lead programming activities and provide oversight of CRO deliverables.
  • Strong analytical, organizational, and communication skills, with a keen eye for detail and the ability to manage multiple priorities in a dynamic, fast-paced environment.
  • Demonstrated leadership in cross-functional teams, experience with global submissions, and knowledge of  database management.

Travel & In Office Presence 

You will be expected to travel periodically based on the needs of the business, including attendance at Together Weeks, Together Days, and functional meetings as requested by the team. Employees are expected to work on hybrid schedules, consistent with local office practices and the terms of the companies in office policy as in effect from time to time.

EEO Statement: 

MBX Biosciences is an Equal Opportunity Employer and is committed to treating all applicants fairly without discrimination. We welcome applications from all individuals, regardless of race, national origin, gender, age, physical characteristics, social origin, disability, union membership, religion, family status, pregnancy, sexual orientation, gender identity, gender expression or any unlawful criterion under applicable law. 

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