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How much do director statistical programming jobs pay per year?

As of Jul 9, 2026, the average yearly pay for director statistical programming in the United States is $280,147.00, according to ZipRecruiter salary data. Most workers in this role earn between $260,500.00 and $322,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Director of Statistical Programming, and why are they important?

To thrive as a Director of Statistical Programming, you need advanced expertise in statistical analysis, programming languages such as SAS or R, and a strong background in clinical trial data, typically supported by a degree in statistics, mathematics, or a related field. Familiarity with regulatory submission processes, CDISC standards, and project management tools is essential, as are relevant certifications like SAS Certified Professional. Leadership, effective communication, and strategic thinking are key soft skills for managing teams and collaborating across departments. These skills ensure high-quality data outputs, regulatory compliance, and successful execution of complex clinical development projects.

What Is the Job of a Director Statistical Programming?

The job of a director of statistical programming oversees the development and implementation of SAS programs to produce statistical analysis datasets. In this career, your responsibilities include managing the team that generates tables and graphs using the SAS programs for applications such as clinical studies. Other duties include participating in the planning and review of statistical analysis and studying reports, abstracts, and manuscripts as required. You collaborate with project leads to contribute to department operations and standards, such as CDISC for clinical research.

How does a Director of Statistical Programming typically collaborate with cross-functional teams in a pharmaceutical or biotech company?

A Director of Statistical Programming regularly works with biostatistics, clinical data management, regulatory affairs, and medical writing teams to ensure that statistical deliverables meet project timelines and regulatory requirements. They coordinate programming efforts across multiple studies, provide leadership and mentorship to programming staff, and help resolve technical or resource-related challenges. Effective collaboration is essential to streamline workflows, maintain data integrity, and ensure clear communication of statistical results within the organization.

What does a Director of Statistical Programming do?

A Director of Statistical Programming oversees teams responsible for the programming and analysis of clinical trial data, ensuring the accuracy and integrity of statistical outputs. They set departmental strategies, manage resources, and ensure compliance with regulatory requirements and industry standards. This role also involves collaborating with other departments, such as biostatistics and clinical operations, to support the successful delivery of statistical analyses for drug development and regulatory submissions. They play a key leadership role in mentoring staff and advancing programming processes and technologies.
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Director Statistical Programming jobs near you
Infographic showing various Director Statistical Programming job openings in the United States as of July 2026, with employment types broken down into 92% Full Time, and 8% Part Time. Highlights an 75% In-person, 8% Hybrid, and 17% Remote job distribution, with an average salary of $280,147 per year, or $134.7 per hour.
Director, Statistical Programming

Director, Statistical Programming

Maze Therapeutics

South San Francisco, CA • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 19 days ago

Job description

The Opportunity
Maze is looking for a Director of Statistical Programming, who will help shape the data foundation of our clinical development programs. In this role you'll collaborate closely with colleagues across Biostatistics, Clinical Data Management, Clinical Operations, and Regulatory Affairs, and oversee external vendors to keep our studies rigorous, high-quality, and ready for regulatory review.
You'll report to the Vice President of Biometrics and lead the strategy and day-to-day execution of statistical programming across multiple clinical studies. Your leadership will ensure we deliver reliable, efficient, and regulatory-compliant programming outputs that drive smarter decisions and advance our therapeutic programs.
The Impact You'll Have
  • Define and implement statistical programming strategy, standards, and best practices across development programs.
  • Lead the design, development, validation, and maintenance of SAS macros, scripts, and applications supporting clinical data analysis, reporting, and regulatory deliverables (e.g., SDTM, ADaM datasets, TLFs).
  • Ensure programming infrastructure is robust, scalable, and compliant with regulatory standards (e.g., FDA 21 CFR Part 11, GxP), and supports reproducibility and audit readiness.
  • Drive automation and standardization of programming workflows to improve efficiency and consistency across studies.
  • Partner closely with Biostatistics, Clinical Data Management, Regulatory Affairs, and IT to define programming requirements, align on analysis/reporting deliverables, and ensure data integrity.
  • Represent the statistical programming function in cross-functional meetings and strategic initiatives.
  • Manage CROs and external programming vendors, including scope, timelines, quality, and budget oversight.
  • Support outsourcing strategy and vendor selection

As a Director, we also expect you to demonstrate the following Leadership Competencies:
  • Communication and Influence
    • Builds communication channels across Maze for sharing information.
    • Influences Senior Management decisions through persuasive arguments.
    • Respectfully addresses differing opinions leading to support of decisions.
  • Teamwork and Collaboration
    • Champions partnerships and connections across Maze.
    • Proactively addresses issues that could result in breakdown of team relationships.
    • Spotlights team and individual contributions in public forums.
  • Execution and Results
    • Addresses gaps and leverages strengths to get best results.
    • Maintains a steadying presence and clarifies priorities during change.
    • Anticipates and removes barriers that put functional/corporate goals at risk.
  • Develop Others and Self
    • Remove barriers to staff development and empowers them to make their own decisions.
    • Stays current on industry trends and keeps direct-reports prepared and responsive.
What We're Looking For
  • An advanced degree in Statistics, Computer Science, Mathematics, or related discipline
    • Master's degree with 10+ years of experience, or Ph.D. with 8+ years of experience
  • A track record of leading statistical programming efforts across multiple clinical studies or regulatory submissions.
  • Strong decision-making skills and the ability to guide teams through ambiguity while influencing across project teams.
  • A collaborative leadership style that emphasizes mentorship, knowledge sharing, and developing others.
  • Deep technical expertise in statistical programming for clinical research, with familiarity in CDISC standards, submission-ready deliverables, and modern programming best practices.

This role follows a hybrid schedule, with an expectation to be onsite at our South San Francisco headquarters at least three days per week.
About Maze Therapeutics
Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing human genetics to develop precision medicines for patients with kidney and metabolic diseases. Our clinical pipeline is anchored by two small molecule programs: MZE829, an APOL1 inhibitor for patients with APOL1-mediated kidney disease, and MZE782, which targets genetic drivers of disease in phenylketonuria (PKU) and chronic kidney disease. We are also advancing a preclinical pipeline through our Compass platform, which links human genetic variants to the biological pathways that drive disease.
Our People
Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients.
Our Core Values
Further Together - Our path is paved with challenges, but with resilience and a team-first mentality, we'll achieve our mission.
Impact Obsessed - We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others.
Stand True - Our integrity is foundational; it guides us no matter the obstacle.
The expected annual salary range for employees located in the San Francisco Bay Area is $229,000 - $279,000. Additionally, this position is eligible for an annual performance bonus.
Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future.
Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy.
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