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How much do senior director statistical programming jobs pay per year?

As of Sep 9, 2026, the average yearly pay for senior director statistical programming in the United States is $99,008.00, according to ZipRecruiter salary data. Most workers in this role earn between $87,000.00 and $107,000.00 per year, depending on experience, location, and employer.

What is the difference between Senior Director Statistical Programming vs Statistical Programming Manager?

AspectSenior Director Statistical ProgrammingStatistical Programming Manager
CredentialsAdvanced degree (MS/PhD), extensive experience in statistical programmingBachelor's or Master's degree, several years of experience
Work EnvironmentStrategic leadership, cross-functional collaboration, high-level decision makingTeam management, project oversight, technical execution
Employer & Industry UsagePharmaceuticals, biotech, clinical research organizationsPharmaceuticals, biotech, clinical research organizations
Search & Comparison IntentUnderstanding senior leadership roles in statistical programmingManaging statistical programming teams and projects

The Senior Director Statistical Programming typically holds a strategic leadership role with extensive experience and oversees multiple teams or departments. In contrast, the Statistical Programming Manager focuses on managing day-to-day project execution and team management. Both roles are vital in clinical research, but the senior director operates at a higher strategic level.

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Senior Director Statistical Programming jobs near you
Infographic showing various Senior Director Statistical Programming job openings in the United States as of September 2026, with employment types broken down into 2% As Needed, 84% Full Time, 12% Part Time, 1% Temporary, and 1% Contract. Highlights an 90% Physical, 3% Hybrid, and 7% Remote job distribution, with an average salary of $99,008 per year, or $47.6 per hour.

Senior Director, Statistical Programming

Wayne, PA • On-site, Remote

Aclaris Therapeutics, Inc.
Pharmaceutical and Medicine Manufacturing • 51 - 200 employees
Learn more about Aclaris Therapeutics, Inc.external

Full-time

Posted 8 days ago

Key responsibilities

  • Lead the statistical programming team by creating workflows, standards, and SOPs.

  • Manage programming timelines and oversee the work of CROs and external vendors.

  • Review and check SAS programs to ensure they meet study requirements and provide support for data review and reporting activities.

Job description

Description
Position Summary:
The Senior Director, Statistical Programming leads our data and analytics efforts. In this role, you will build and manage the statistical programming strategies, SAS frameworks, and team standards needed to support Aclaris's clinical programs. You will manage programmers and CROs, oversee programming activities and provide timely support to the cross-functional teams on statistical programming matters according to the project strategies and requests. This role will be hands-on initially with the opportunity to build the function as our clinical programs advance.
Essential Duties and Responsibilities:
  • Lead the statistical programming team by creating clear workflows, standards, and standard operating procedures (SOPs).
  • Manage programming timelines for clinical studies and oversee the work of CROs and external vendors.
  • Partner with Biostatistics, Data Management, Clinical Operations, Regulatory, Pharmacovigilance, and other functions to deliver high-quality data deliverables in timely fashion.
  • Help develop new data review tools and reporting applications alongside the Biostatistics team.
  • Review and check SAS programs created by CROs to ensure they meet standard (e.g., SDTM, ADaM) and custom (e.g., non-standard datasets and TFLs) study requirements.
  • Develop SAS infrastructure and programming processes to make routine reporting and ad hoc data requests more efficient.
  • Review and provide expert feedback on study documents like SAPs, DMPs, CRFs, data and TFL programming specifications.
  • Hire, train, and mentor a team of programmers to support our growing clinical trials.
  • Run ad hoc data analyses as needed to support business decisions.

Additional Responsibilities:
Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.
Requirements
Required Education and Experience:
  • Master's Degree in Statistics, Biostatistics, Mathematics, or a related field.
  • At least 10 years of clinical trial programming experience in the pharma or biotech industry.

Required Knowledge, Skills, Abilities & Behaviors:
  • Strong SAS programming skills, with some experience using other tools like R.
  • Deep understanding of CDISC standards, including SDTM, ADaM, and controlled terminologies.
  • Great organizational skills and the ability to balance multiple tasks in a fast-paced environment.
  • Strong communication skills and the ability to explain technical data concepts to other teams.
  • Proven experience managing CROs and external data vendors.
  • A supportive leader who values a collaborative and psychologically safe team environment.
  • Good working knowledge of FDA, EMA, and ICH regulatory guidelines.
  • Comfortable working and leading in a fully remote, virtual environment.
  • Willing and able to travel for business as needed.

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