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Director Preclinical Development Jobs (NOW HIRING)

Hands-on, non-administrative preclinical R&D experience at a company that develops its own drug assets in-house and has taken programs to the clinic. * Direct experience with ADCs and/or bispecific ...

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How much do director preclinical development jobs pay per year?

As of Aug 22, 2026, the average yearly pay for director preclinical development in the United States is $92,386.00, according to ZipRecruiter salary data. Most workers in this role earn between $70,000.00 and $108,500.00 per year, depending on experience, location, and employer.

What is a director preclinical development?

A Director of Preclinical Development oversees the early-stage research and testing of drug candidates before they enter clinical trials. They manage preclinical studies, ensuring regulatory compliance, safety, and efficacy assessments. This role involves coordinating with cross-functional teams, external partners, and regulatory agencies to advance promising compounds. Strong expertise in toxicology, pharmacology, and regulatory guidelines is essential. The director plays a key role in shaping the preclinical strategy to support successful drug development.

What are the typical responsibilities and team dynamics for a director preclinical development?

A Director of Preclinical Development is responsible for overseeing the planning, execution, and management of preclinical research programs, ensuring that studies meet scientific, regulatory, and project milestones. You will typically work with cross-functional teams including toxicologists, pharmacologists, regulatory affairs professionals, and external partners, fostering collaboration throughout the drug development process. The role often involves reviewing study designs and data, preparing regulatory submissions, and providing strategic direction to advance compounds toward clinical testing. Working closely with upper management, you'll play a key part in shaping research priorities and resource allocation. This position offers significant influence over drug development strategies and opportunities for advancement to higher executive or scientific leadership roles.

What are the key skills and qualifications needed to thrive in the director preclinical development position, and why are they important?

To thrive as a Director Preclinical Development, you need deep expertise in pharmaceutical or biotechnology research, strong project management abilities, and an advanced degree (Ph.D., Pharm.D., or equivalent) in a life sciences field. Familiarity with regulatory guidelines (such as GLP), experience using data management and statistical analysis software, and prior leadership roles in preclinical studies are essential. Exceptional communication, problem-solving, and team leadership skills set candidates apart in managing multidisciplinary teams and collaborative projects. These competencies are crucial for successfully guiding drug candidates through preclinical stages while ensuring regulatory compliance and timely project delivery.

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Infographic showing various Director Preclinical Development job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 83% Full Time, 14% Part Time, and 2% Contract. Highlights an 90% Physical, 3% Hybrid, and 7% Remote job distribution, with an average salary of $92,386 per year, or $44.4 per hour.

CCHS - Assistant/Associate Professor Preclinical Development and Clinical Translation - Tenure/Tenur

The University of Alabama

Montevallo, AL • On-site

Full-time

Posted 17 days ago


University Of Alabama rating

7.1

Company rating: 7.1 out of 10

Based on 60 frontline employees who took The Breakroom Quiz

411th of 620 rated colleges and universities


Job description

Department/Organization
208301 - Translational Science and Medicine


Rank
Assistant/Associate Professor


Position Summary
The University of Alabama's newly established Department of Translational Science and Medicine within the College of Community Health Sciences (CCHS) is seeking a dynamic and innovative faculty member with a passion for revolutionizing medicine. This is a unique opportunity to build a research program at the exciting intersection of Translational Science and Medicine. We seek an exceptional physician-scientist (practicing or non-practicing) with an MD/PhD or equivalent dual degree who possesses deep expertise in patient-centered research, preclinical development, and the design, formulation, and clinical translation of advanced drug delivery systems, particularly nanomedicines. The successful candidate will establish an innovative, extramurally funded research program that bridges fundamental physicochemical and biological principles with real-world clinical needs. Appointments to the faculty of The University of Alabama are based on the personnel requirements of the University’s academic programs and on the goal of achieving and maintaining excellence in its teaching, research, and service/academic citizenship activities.


Detailed Position Information
The newly established Department of Translational Science and Medicine is seeking a physician-scientist to significantly contribute to the department's mission of revolutionizing medicine through direct clinical translation. The ideal candidate will leverage their dual degree (MD/PhD or equivalent) and expertise to establish an innovative, extramurally funded research program focused on drug product development.
Key Research Focus Areas:
a) Establishing programs that bridge fundamental physicochemical and biological principles with real-world clinical need.
b) Driving the bench-to-bedside process for novel therapies.
c) Focusing on advanced drug product development.
Clinical Integration and Collaboration:
The successful candidate will be expected to actively integrate their research program with CCHS practicing physicians to:
1) Collaboratively define critical challenges and opportunities in patient care that can be addressed by novel drug product solutions.
2) Leverage clinical expertise from CCHS staff to ensure the translational research (including the design, formulation, and clinical translation of advanced drug delivery systems) is directly applicable and feasible within a clinical setting.
3) Establish a pipeline that moves discoveries from the lab to practice, ensuring the research directly informs and improves patient outcomes within the health system.
Key Responsibilities
1) Maintain an active research framework targeting advanced delivery systems and nanomedicines.
2) Proactively secure extramural funding to support and sustain programmatic research goals.
3) Publish high-impact research findings in peer-reviewed scientific journals.
4) Collaborate closely with interdisciplinary teams across the university and with external partners.
5) Develop and teach academic courses at both the undergraduate and graduate levels.
6) Mentor and train undergraduate students, PhD candidates, and junior researchers.
7) Participate in departmental, college, and university committee assignments to support the newly established department.


Minimum Qualifications
An MD/PhD or equivalent dual degree.
Deep expertise in patient-centered research, preclinical development, and the design, formulation, and clinical translation of advanced drug delivery systems, particularly nanomedicines.


Preferred Qualifications
Evidence of successful interdisciplinary collaboration between basic science and clinical departments. Experience with novel delivery platforms like targeted delivery methods relevant to chronic conditions. Proven ability to communicate fluently across the distinct languages of basic scientists (physicochemical principles) and practicing clinicians (patient care protocols and outcomes). Experience with, or the clear ability to develop and teach, courses that explicitly integrate clinical pathophysiology with pharmaceutical science/biomedical engineering at the graduate and undergraduate levels, aligning with the need to bridge fundamental principles with real-world clinical needs. Experience mentoring students (UG, PhD) and junior researchers from both clinical and non-clinical backgrounds, demonstrating the ability to cultivate a truly interdisciplinary lab environment.


Instructions and Required Materials for Application
1) A detailed letter outlining your interest in this position and how your expertise aligns with the department's vision. 2) A comprehensive CV detailing your academic background, research experience, and publications. 3) A document (max. 3 pages) summarizing your past research achievements, current projects, and future research goals. Crucially, this must specifically highlight your preclinical experiences in drug discovery and development, and your ability and experience to integrate findings clinically. 4) A statement (max. 1 page) describing your teaching interests and approach. 5) A list of five professional references with their contact information. For more information, please contact Dr. M. N. V. Ravi Kumar at mnvrkumar@ua.edu.


About the Division/College/School
The College of Community Health Sciences (CCHS) was founded in 1972 by William Willard, MD, author of the “Willard Report” and considered the “Father of Family Medicine,” with a mandate to train family physicians for Alabama, particularly its rural areas. The College also provides medical student education as the Tuscaloosa Regional Campus of the four-campus University of Alabama School of Medicine, based at UAB in Birmingham. The College’s mission focuses on improving the health of individuals and communities in Alabama and the region through leadership in medical education and primary care; the provision of high-quality, accessible health care services; and scholarship.
CCHS is sponsor of the UA Family Medicine Residency and seven fellowships for family physicians. The Residency, a 16-16-16 program now in its 45th year, is the second largest family medicine residency in the country. Of the more than 470 Residency graduates, 85% practice in the five-state area of the Southeast, with half in rural areas, and comprise 1 of 7 family physicians practicing in Alabama. Nearly 900 medical students have completed their clinical training at the College since 1974, entering Family Medicine and primary care careers at more than twice the national average.
The College’s nationally recognized Rural Pipeline Programs and the Institute for Rural Health Research, along with basic sciences, social sciences, and health professional faculty and resources on the UA campus and innumerable specialty and medical research faculty among the School of Medicine faculty, create a uniquely resource-rich environment for a medical educator. The College’s clinical enterprise also conducts 150,000 ambulatory visits and more than 10,000 admissions a year to a broad patient population, including UA faculty and staff and the general population of West Alabama.
For more information about the College, visit http://cchs.ua.edu


About the University
The University of Alabama is located in Tuscaloosa, Alabama, named one of Travel + Leisure’s 25 Best College Towns and Cities in the U.S. As one of the nation’s premier universities, UA offers bachelor’s, master's and doctoral degrees in nearly 200 fields of study. With more than 1,400 acres of tree-lined academic core campus and over 300 state-of-the art facilities, UA has been ranked among the most beautiful and most impressive college campuses in the South, in the state of Alabama and in the nation.
In Fall 2023, the Capstone set a new enrollment record with more than 39,000 students, including more than 8,200 in the freshman class. The current enrollment includes students from every county in Alabama, every state in the nation and 92 countries around the world. More than 1,100 National Merit Scholars are currently enrolled, making UA one of the largest enrolling institutions of the scholars in the country.
UA was recently recognized as a Top Producing Institution of Fulbright U.S. students for the seventh time in nine years, as well as a Top Producing Institution of Fulbright U.S. Scholars for the first time. UA is one of only 12 universities in the nation to receive both honors.
For reasons like this, the University made Forbes list of America’s Top Colleges for 2023 and Time magazine’s list of Top 50 Best Colleges for Future Leaders. It also made Princeton Review’s list of Top Value Colleges.
UA is also designated among the top doctoral research universities in the United States in the Carnegie Classification of Institutions of Higher Education. One of the fastest growing major research institutions in the nation, UA saw a 21% increase in sponsored awards in the 2023 fiscal year.
Since 2015, UA has invested over $1.1 billion in the physical campus, adding more than 2.55 million gross square feet of space, over 150 new research-intensive faculty, signature research areas (e.g., “The Alabama Research Institutes”), and a growing number of partnerships with industry and with state and federal agencies.
The University employs nearly 2,100 faculty and over 4,500 staff, with 52 UA researchers included in the National Academy of Inventors. An additional 40 current faculty have received the NSF CAREER Award, the nation’s most prestigious recognition of top performing young scientists in disciplines ranging from nanoscience and engineering to biological sciences.


Background Investigation and EEO Statement
Background Investigation Statement: Prior to hiring, the final candidate(s) must successfully pass a pre-employment background investigation and information obtained from social media and other internet sources. A prior conviction reported as a result of the background investigation DOES NOT automatically disqualify a candidate from consideration for this position. A candidate with a prior conviction or negative behavioral red flags will receive an individualized review of the prior conviction or negative behavioral red flags before a hiring decision is made.
Equal Employment Opportunity: The University of Alabama is an Equal Employment/Equal Educational Opportunity Institution. All qualified applicants will receive consideration for employment or volunteer status without regard to any legally protected basis and will not be discriminated against because of their protected status. Applicants and employees of this institution are protected under Federal law from discrimination on several bases. More information is available in the EEOC’s Know Your Rights: Workplace (https://www.eeoc.gov/sites/default/files/2023-06/22-088_EEOC_KnowYourRights6.12ScreenRdr.pdf) discrimination is illegal poster.
The University of Alabama affirms its longstanding commitment to institutional neutrality, free speech, and academic freedom.


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