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Director Peptide Jobs (NOW HIRING)

The Project Director will drive transformational performance in delivery of Peptide API projects in the United States through adoption of best-in-class technology, cross-functional alignment with ...

The Project Director will drive transformational performance in delivery of Peptide API projects in the United States through adoption of best-in-class technology, cross-functional alignment with ...

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Director Peptide information

What does a Director of Peptide do?

A Director of Peptide is a senior leader responsible for overseeing peptide research, development, and production within a biotechnology or pharmaceutical company. They manage teams working on peptide synthesis, optimization, and characterization to support drug discovery or manufacturing goals. Additionally, they develop strategic plans, ensure compliance with regulations, and collaborate with cross-functional teams to advance peptide-related projects from concept to market. Their role involves both scientific expertise and strong leadership skills to drive innovation and achieve business objectives.

How does a Director of Peptide typically collaborate with cross-functional teams within a pharmaceutical organization?

A Director of Peptide often works closely with various departments such as research and development, manufacturing, regulatory affairs, and quality assurance. This collaboration ensures that peptide discovery, synthesis, and scale-up processes align with project timelines and regulatory requirements. The role frequently involves leading multidisciplinary project teams, facilitating communication between scientists and business stakeholders, and driving strategic decisions to advance peptide therapeutics from concept to clinical development.

What are the key skills and qualifications needed to thrive as a Director of Peptide, and why are they important?

To thrive as a Director of Peptide, you need advanced expertise in peptide chemistry, drug development, and a PhD or equivalent experience in biochemistry or related fields. Familiarity with analytical instrumentation (e.g., HPLC, LC-MS), regulatory compliance systems, and project management software is typically required. Leadership, strategic thinking, and effective communication are crucial soft skills for guiding teams and cross-functional collaborations. These competencies ensure successful peptide project execution, innovation, and alignment with organizational goals in the pharmaceutical or biotech industry.
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Infographic showing various Director Peptide job openings in the United States as of June 2026, with employment types broken down into 1% As Needed, 86% Full Time, and 13% Part Time. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution.
Director, Peptide Process Development

Director, Peptide Process Development

Alnylam Pharmaceuticals

Cambridge, MA • On-site

$197K - $266K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 6 days ago


Job description

Overview:
The Director of Peptide & Peptide-Oligonucleotide Conjugate (POC) Process Development will provide technical leadership for the development, scale-up, and external manufacture of peptide and POC active pharmaceutical ingredients. This role is accountable for advancing robust, scalable, and regulatory-ready processes from early development through clinical and commercial supply.
This position requires a balance of hands-on technical expertise, strong CDMO management experience, and cross-functional leadership to deliver peptide and POC processes that are fit for development, manufacture, and future scale
This position is onsite and will be primarily located in Cambridge, MA.
Responsibilities:
  • Lead process development, optimization, scale up, and characterization of peptides and contribute to the development of peptide oligonucleotide conjugate (POC) APIs with internal stakeholders.
  • Serve as the technical lead for peptide and POC processes from development through external GMP manufacture.
  • Evaluate, select, and enable CDMOs; lead process transfer and external manufacturing activities.
  • Author and review technical and regulatory documentation supporting API manufacture and filings.
  • Integrate CMC process activities within TOQ and extended program teams.
  • Contribute to long-term peptide and POC platform strategy and delivery.

Qualifications:
  • PhD in a relevant scientific discipline with 10+ years of industry experience in peptide and/or conjugate process development.
  • Demonstrated expertise in peptide API development, scale up, and process characterization.
  • Experience in process development, optimization, scale-up, and process characterization of peptide-drug conjugates and/or oligonucleotide conjugates.
  • Proven experience leading process transfer and external CDMO-based GMP manufacturing.
  • Experience supporting CMC documentation and regulatory filings.
  • Ability to function as a technical owner within cross-functional program teams.

#LI-KB1 #LI-Onsite
U.S. Pay Range
$197,100.00 - $266,700.00
The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).
Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.
Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers
About Alnylam
We are the leader in RNAi therapeutics - a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.
At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.