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Clinical Operations Manager Jobs in Rochester, MN

District Sales Manager About Limitless Male Medical Limitless Male Medical Clinic is a leader in ... All team members are expected to support clinic operations and patient needs as they arise, within ...

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Clinical Operations Manager information

See Rochester, MN salary details

$34.2K

$95.7K

$182.1K

How much do clinical operations manager jobs pay per year?

As of Aug 17, 2026, the average yearly pay for clinical operations manager in Rochester, MN is $95,713.00, according to ZipRecruiter salary data. Most workers in this role earn between $70,800.00 and $110,800.00 per year, depending on experience, location, and employer.

What is a clinical operations manager?

Clinical Operations Managers are professionals responsible for overseeing the day-to-day administrative and operational functions of clinical trials or healthcare facilities. They ensure that clinical protocols are followed, resources are efficiently allocated, and regulatory compliance is maintained. These managers coordinate between healthcare staff, researchers, and external partners to facilitate smooth clinical operations and high-quality patient care. Their role is essential in ensuring that clinical services or trials are delivered effectively, safely, and on schedule.

What does a clinical operations manager do?

A clinical operations manager or director is a health care professional who oversees the operations of a medical facility. Their duties include meeting regularly with department heads, reading assessments of employee productivity, and managing administrative tasks, such as budgeting and billing. Qualifications for a clinical operations manager include experience in medical administration, management skills, and organizational skills. An advanced degree in public health or health administration can significantly improve your job opportunities.

What are the key skills and qualifications needed to thrive as a clinical operations manager, and why are they important?

To thrive as a Clinical Operations Manager, you need expertise in clinical trial management, regulatory compliance, and healthcare operations, usually supported by a degree in a health-related field and relevant experience. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and certifications such as ACRP or SOCRA are commonly required. Strong leadership, problem-solving abilities, and effective communication are essential soft skills for this role. These skills ensure efficient trial execution, regulatory adherence, and successful coordination across teams and stakeholders.

What are the main challenges clinical operations managers face when overseeing multiple clinical trials simultaneously?

Clinical Operations Managers often juggle several clinical trials at once, which can present challenges such as maintaining consistent quality across studies, ensuring timely patient recruitment, and managing diverse teams. They must coordinate with cross-functional departments, address regulatory compliance, and troubleshoot unforeseen issues, all while staying on schedule and within budget. Effective organizational skills, proactive communication, and adaptability are essential for overcoming these challenges and ensuring successful trial outcomes.

What is the difference between Clinical Operations Manager vs Clinical Research Coordinator?

AspectClinical Operations ManagerClinical Research Coordinator
CredentialsBachelor's degree in health sciences, management experienceBachelor's degree in health or life sciences, research training
Work EnvironmentOversees multiple clinical trials, manages teamsAssists with daily trial activities, data collection
Employer & IndustryPharmaceutical companies, CROs, hospitalsResearch institutions, hospitals, clinical sites

The Clinical Operations Manager focuses on overseeing entire clinical trial operations, managing teams, and ensuring compliance. In contrast, the Clinical Research Coordinator handles the day-to-day activities at trial sites, such as patient recruitment and data collection. Both roles require related credentials and work within the clinical research industry, but their responsibilities and scope differ significantly.

How much do clinical operations managers make?

Clinical operations managers in the US typically earn between $80,000 and $130,000 annually, with the median salary around $105,000. Compensation varies based on experience, location, and the size of the organization, and often includes benefits such as health insurance and bonuses.
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What cities near Rochester, MN are hiring for Clinical Operations Manager jobs?

Cities near Rochester, MN with the most Clinical Operations Manager job openings:

Infographic showing various Clinical Operations Manager job openings in Rochester, MN as of August 2026, with employment types broken down into 80% Full Time, 17% Part Time, 1% Temporary, and 2% Contract. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution, with an average salary of $95,713 per year, or $46 per hour.

Manager - Clinical Nurse Specialist

Mayo Clinic

Rochester, MN • On-site

Full-time

Medical, Dental, Vision, Retirement

Posted 13 days ago


Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 699 frontline employees who took The Breakroom Quiz

128th of 887 rated healthcare providers


Job description

The Clinical Nurse Specialist manager provides leadership based on the vision, mission, philosophy, and core values of Mayo Clinic and the Department of Nursing. The Clinical Nurse Specialist manager plans, directs, coordinates, and evaluates the operational, fiscal, and personnel activities within defined areas of practice and allocates direct report resources to ensure the provision of high quality patient care. The role includes ongoing collaboration and communication utilizing participative decision making when appropriate. The Clinical Nurse Specialist manager is responsible for promoting a collaborative approach to improve the quality of patient care and value to patients. The manager applies current nursing and leadership theories to coordinate direct report activities. The Clinical Nurse Specialist manager acts as a resource and facilitates collaboration between nursing personnel and other healthcare disciplines throughout the organization and within the healthcare community. The Clinical Nurse Specialist manager contributes to the strategic planning process and attainment of goals of the organization. The Clinical Nurse Specialist manager is responsible for the orientation, supervision, coordination, and triage of assignments for staff that report to them. The Clinical Nurse Specialist manager coaches and mentors the staff that report to them. The Clinical Nurse Specialist manager serves as a leader participating in and providing direction for departmental and institutional goals and evidence based practice initiatives. The Clinical Nurse Specialist manager develops and maintains effective relationships with a variety of individuals, both internally and externally.
This role is eligible for TN sponsorship. Successful sponsorship will require state licensure and completion of the VisaScreen or equivalent certification.

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. 

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law".  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
  • Master's degree with a major in nursing with a Clinical Nurse Specialist focus. Doctoral Degree - DNP or PhD in Nursing preferred.
  • Five years of successful work experience in nursing with three years as a Clinical Nurse Specialist. 
  • Previous experience in supervisory or managerial position preferred. 

License and Certifications: 

  • Current RN license by applicable state requirements. 
  • Current APRN license by applicable state requirements. Maintains current Basic Life Support for Health Care Providers from one of the following programs:
  • American Heart Association or American Red Cross. Additional state licensure(s) and/or specialty certification/training as required by the work area.

What Mayo Clinic employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom


Mayo Clinic logo

About Mayo Clinic

Sourced by ZipRecruiter

Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919