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Clinical Operations Manager Jobs in Chicago, IL (NOW HIRING)

Operations Supervisor

Grayslake, IL · On-site

$70K - $85K/yr

This role ensures operational efficiency, accountability, and compliance across clinical services ... management, scheduling expectations, and other organizational responsibilities. This includes ...

This role ensures operational efficiency, accountability, and compliance across clinical services ... management, scheduling expectations, and other organizational responsibilities. This includes ...

Service Operations Manager Location: Onsite Reports to: Director, Service Salary Range: $115,000 ... Operating in more than 100 countries worldwide, Alma combines advanced technology, clinical ...

* Where state and federal laws/regulations allow, accountable for performing day-to-day non-clinical ... Manages core pharmacy workflow and drives excellence in pharmacy operations. Coordinates and ...

* Where state and federal laws/regulations allow, accountable for performing day-to-day non-clinical ... Manages core pharmacy workflow and drives excellence in pharmacy operations. Coordinates and ...

* Where state and federal laws/regulations allow, accountable for performing day-to-day non-clinical ... Manages core pharmacy workflow and drives excellence in pharmacy operations. Coordinates and ...

* Where state and federal laws/regulations allow, accountable for performing day-to-day non-clinical ... Manages core pharmacy workflow and drives excellence in pharmacy operations. Coordinates and ...

* Where state and federal laws/regulations allow, accountable for performing day-to-day non-clinical ... Manages core pharmacy workflow and drives excellence in pharmacy operations. Coordinates and ...

Showing results 41-60

Clinical Operations Manager information

See Chicago, IL salary details

$36.1K

$101K

$192.1K

How much do clinical operations manager jobs pay per year?

As of Sep 2, 2026, the average yearly pay for clinical operations manager in Chicago, IL is $100,994.00, according to ZipRecruiter salary data. Most workers in this role earn between $74,700.00 and $116,900.00 per year, depending on experience, location, and employer.

What is a clinical operations manager?

Clinical Operations Managers are professionals responsible for overseeing the day-to-day administrative and operational functions of clinical trials or healthcare facilities. They ensure that clinical protocols are followed, resources are efficiently allocated, and regulatory compliance is maintained. These managers coordinate between healthcare staff, researchers, and external partners to facilitate smooth clinical operations and high-quality patient care. Their role is essential in ensuring that clinical services or trials are delivered effectively, safely, and on schedule.

What does a clinical operations manager do?

A clinical operations manager or director is a health care professional who oversees the operations of a medical facility. Their duties include meeting regularly with department heads, reading assessments of employee productivity, and managing administrative tasks, such as budgeting and billing. Qualifications for a clinical operations manager include experience in medical administration, management skills, and organizational skills. An advanced degree in public health or health administration can significantly improve your job opportunities.

What are the key skills and qualifications needed to thrive as a clinical operations manager, and why are they important?

To thrive as a Clinical Operations Manager, you need expertise in clinical trial management, regulatory compliance, and healthcare operations, usually supported by a degree in a health-related field and relevant experience. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and certifications such as ACRP or SOCRA are commonly required. Strong leadership, problem-solving abilities, and effective communication are essential soft skills for this role. These skills ensure efficient trial execution, regulatory adherence, and successful coordination across teams and stakeholders.

What are the main challenges clinical operations managers face when overseeing multiple clinical trials simultaneously?

Clinical Operations Managers often juggle several clinical trials at once, which can present challenges such as maintaining consistent quality across studies, ensuring timely patient recruitment, and managing diverse teams. They must coordinate with cross-functional departments, address regulatory compliance, and troubleshoot unforeseen issues, all while staying on schedule and within budget. Effective organizational skills, proactive communication, and adaptability are essential for overcoming these challenges and ensuring successful trial outcomes.

What is the difference between Clinical Operations Manager vs Clinical Research Coordinator?

AspectClinical Operations ManagerClinical Research Coordinator
CredentialsBachelor's degree in health sciences, management experienceBachelor's degree in health or life sciences, research training
Work EnvironmentOversees multiple clinical trials, manages teamsAssists with daily trial activities, data collection
Employer & IndustryPharmaceutical companies, CROs, hospitalsResearch institutions, hospitals, clinical sites

The Clinical Operations Manager focuses on overseeing entire clinical trial operations, managing teams, and ensuring compliance. In contrast, the Clinical Research Coordinator handles the day-to-day activities at trial sites, such as patient recruitment and data collection. Both roles require related credentials and work within the clinical research industry, but their responsibilities and scope differ significantly.

More about Clinical Operations Manager jobs

What are the most commonly searched types of Clinical Operations jobs in Chicago, IL?

The most popular types of Clinical Operations jobs in Chicago, IL are:

What are popular job titles related to Clinical Operations Manager jobs in Chicago, IL?

For Clinical Operations Manager jobs in Chicago, IL, the most frequently searched job titles are:

What cities near Chicago, IL are hiring for Clinical Operations Manager jobs?

Cities near Chicago, IL with the most Clinical Operations Manager job openings:

Infographic showing various Clinical Operations Manager job openings in Chicago, IL as of August 2026, with employment types broken down into 83% Full Time, 14% Part Time, 1% Temporary, 1% Contract, and 1% Nights. Highlights an 94% Physical, 2% Hybrid, and 4% Remote job distribution, with an average salary of $100,994 per year, or $48.6 per hour.

Sys VP Clinical Operations - Ambulatory Surgery

CommonSpirit Health

Chicago, IL • Remote

$111 - $155.50/hr

Full-time

Re-posted 11 days ago


CommonSpirit Health rating

7.0

Company rating: 7.0 out of 10

Based on 541 frontline employees who took The Breakroom Quiz

421st of 898 rated healthcare providers


Job description


Job Summary and Responsibilities

As the System Vice President of Clinical Operations for Ambulatory Surgery at CommonSpirit Health you are primarily responsible for ensuring the ongoing clinical excellence, maintaining rigorous quality standards, and guaranteeing regulatory adherence across CommonSpirit's extensive network of multi-regional ambulatory surgery centers (ASCs). Operating remotely, this position requires substantial nationwide travel to provide centralized strategic oversight and direct operational guidance.

Every day you will be tasked with standardizing and optimizing clinical processes, fostering a culture of continuous improvement, and ultimately ensuring the consistent delivery of safe, effective, and high-quality patient care throughout the entire ASC network. Furthermore, this leader will play a crucial role in supporting growth initiatives, embedding best practices aligned with the CommonSpirit mission, and driving superior clinical outcomes and patient satisfaction.

To be successful in the role the following competencies are critical:

  • System-Wide Clinical and Quality Leadership: Provide strategic and operational leadership for all clinical aspects across CommonSpirit's ASC network, driving consistent quality, safety, and patient satisfaction through system-wide policies, quality programs, and continuous improvement initiatives.
  • Regulatory Compliance & Risk Management: Ensure comprehensive adherence to all federal, state, and accreditation regulations (e.g., CMS, AAAHC), overseeing regulatory readiness, surveys, and developing robust clinical risk management programs for all ASCs.
  • Operational Excellence & Efficiency: Standardize clinical workflows, optimize processes, and integrate innovative practices to enhance efficiency, reduce variation, and improve patient throughput across the ASC portfolio, leveraging data for performance monitoring and corrective actions.
  • Team Leadership & Development: Remotely recruit, mentor, and develop a high-performing clinical leadership team, fostering a collaborative, patient-centered environment and implementing comprehensive clinical training and competency assessment programs across all ASC staff.
  • Strategic Growth & Integration: Actively contribute to strategic planning by providing clinical expertise, supporting the integration of new ASCs, evaluating new services and technologies, and participating in due diligence for potential growth opportunities.
  • Stakeholder Collaboration & Communication: Build strong relationships with internal CommonSpirit stakeholders and external partners, effectively communicating clinical performance, challenges, and strategic opportunities to executive leadership and representing the system externally.
Job Requirements

Required

  • Education/License:
    • Bachelor's Degree in Nursing (BSN).
    • Active, unrestricted Registered Nurse (RN) license with willingness to obtain additional state licenses as needed.
  • Experience:
    • 10-15 years of progressive clinical leadership experience in an Ambulatory Surgical Center (ASC) setting, preferably within a multi-site health system.
    • 5-7 years in a senior executive leadership role overseeing multiple ASCs across diverse regions.
    • Strong background in quality improvement, patient safety, and regulatory compliance.
    • Proven experience developing and implementing system-wide clinical policies and best practices across a dispersed network.
    • Demonstrated ability to manage and develop clinical teams, drive operational efficiencies, and achieve clinical excellence in a remote/multi-site capacity.

Preferred

  • Master's Degree (MSN, MHA, MBA, or related clinical/administrative field) strongly preferred.

#LI-CSH

Where You'll Work

Inspired by faith. Driven by innovation. Powered by humankindness. CommonSpirit Health is building a healthier future for all through its integrated health services. As one of the nation’s largest nonprofit Catholic healthcare organizations, CommonSpirit Health delivers more than 20 million patient encounters annually through more than 2,300 clinics, care sites and 137 hospital-based locations, in addition to its home-based services and virtual care offerings. CommonSpirit has more than 157,000 employees, 45,000 nurses and 25,000 physicians and advanced practice providers across 24 states and contributes more than $4.2 billion annually in charity care, community benefits and unreimbursed government programs. Together with our patients, physicians, partners, and communities, we are creating a more just, equitable, and innovative healthcare delivery system.


Pay Range
$111.00 - $155.50/hr

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