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Clinical Operation Manager Jobs (NOW HIRING)

Mai Placement

Clinical Director

Brooklyn, NY

$87K - $119K/yr

Lead and oversee day-to-day clinical operations * Manage in-house clinical teams, field nurses, and clinical leadership staff * Oversee approximately 30-40 field nurses conducting patient assessments

Grand Mental Health

Clinical Operations Manager

Tulsa, OK · On-site

$60K - $70K/yr

Description The Clinical Operations Manager is responsible for the administrative and day to day operational oversight of ARC clinical programming and multidisciplinary clinical support functions.

Galderma

Global Head of Clinical Operations

Boston, MA · On-site

Financial & Vendor Management * Oversee global clinical operation budgets, ensuring financial discipline and alignment with portfolio priorities. * Establish and manage strategic partnerships with ...

Actalent

Clinical Operations Manager

Bellflower, CA

$130K - $150K/yr

The Clinical Operations Manager ensures compliance with operational policies, objectives, and initiatives, and plays a key role in budget development and performance monitoring. The position also ...

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Clinical Operation Manager information

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$35K

$98K

$186.5K

How much do clinical operation manager jobs pay per year?

As of Jun 16, 2026, the average yearly pay for clinical operation manager in the United States is $98,039.00, according to ZipRecruiter salary data. Most workers in this role earn between $72,500.00 and $113,500.00 per year, depending on experience, location, and employer.

What are some common challenges Clinical Operation Managers face when coordinating multi-site clinical trials?

Clinical Operation Managers often encounter challenges such as ensuring consistent protocol adherence across all sites, managing communication among geographically dispersed teams, and maintaining timelines despite unexpected delays. They must also address regulatory differences between sites and troubleshoot issues related to patient recruitment and data collection. Success in this role requires strong organizational skills, adaptability, and effective collaboration with investigators, coordinators, and regulatory personnel.

What are the key skills and qualifications needed to thrive as a Clinical Operation Manager, and why are they important?

To thrive as a Clinical Operation Manager, you need expertise in clinical project management, regulatory compliance, and a background in healthcare or life sciences, often supported by a relevant degree. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) tools, and certifications such as PMP or Six Sigma are commonly required. Strong leadership, problem-solving abilities, and excellent communication skills set top performers apart in this role. These competencies are essential for ensuring efficient clinical operations, maintaining regulatory standards, and leading teams to deliver successful trial outcomes.

What are Clinical Operation Managers?

Clinical Operation Managers are professionals responsible for overseeing the daily operations of clinical research sites, medical facilities, or departments. They ensure that clinical trials or healthcare services are conducted efficiently, comply with regulations, and meet quality standards. Their duties often include supervising staff, managing budgets, implementing policies, and coordinating between various teams. Clinical Operation Managers play a crucial role in ensuring that patient care and research activities run smoothly and effectively.

What is the difference between Clinical Operation Manager vs Clinical Research Coordinator?

AspectClinical Operation ManagerClinical Research Coordinator
CredentialsBachelor's degree in health sciences, life sciences, or related field; often with project management certificationsBachelor's degree in health sciences, nursing, or related field; often with research-specific training
Work EnvironmentOversees multiple clinical trials, manages teams, and ensures compliance at a departmental levelCoordinates daily activities of clinical trials, interacts directly with participants and investigators
Employer & IndustryPharmaceutical companies, biotech firms, hospitals, research institutionsResearch sites, hospitals, academic institutions, contract research organizations

The Clinical Operation Manager focuses on overseeing clinical trial operations, managing teams, and ensuring compliance across projects. In contrast, the Clinical Research Coordinator handles the day-to-day activities of specific trials, working closely with participants and investigators. Both roles require relevant healthcare or science credentials, but their scope and responsibilities differ significantly.

More about Clinical Operation Manager jobs
What cities are hiring for Clinical Operation Manager jobs? Cities with the most Clinical Operation Manager job openings:
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What states have the most Clinical Operation Manager jobs? States with the most job openings for Clinical Operation Manager jobs include:
What job categories do people searching Clinical Operation Manager jobs look for? The top searched job categories for Clinical Operation Manager jobs are:
Clinical Operation Manager jobs near you

Clinical Operations Manager

UNC Health Appalachian

Linville, NC • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 25 days ago

Job description

Clinical Operations Manager – Emergency & Med-Surg

Location: Linville, North Carolina | Full-Time | Leadership Role

Why You’ll Love Working Here

As the Clinical Operations Manager for the Emergency and Med-Surg Departments at UNC Health Appalachian, you will play a vital leadership role in ensuring exceptional patient care, operational excellence, and staff engagement. This position offers the opportunity to lead dynamic clinical teams in a collaborative healthcare environment committed to quality, safety, and compassionate care. Join a mission-driven organization where your leadership directly impacts patient outcomes and team success.

  • Compensation: Compensation is commensurate upon education, experience, certification, and internal equity
  • Schedule: Full-time leadership position with 24/7 operational accountability
  • Benefits: Comprehensive medical/dental/vision coverage, retirement with employer match, paid time off, tuition reimbursement, paid parental leave, wellness incentives, and employee discounts
What You’ll Do as a Clinical Operations Manager
  • Provide operational and clinical leadership for the Emergency and Med-Surg Departments on a 24/7 basis
  • Ensure safe, high-quality, and efficient patient care delivery aligned with organizational goals and regulatory standards
  • Lead, mentor, and support nursing and clinical staff while fostering professional growth and accountability
  • Collaborate with physicians, interdisciplinary teams, and leadership to optimize patient outcomes and departmental performance
  • Support staffing, scheduling, workflow management, and resource allocation to maintain operational efficiency
  • Respond to emergent situations and provide clinical support as needed within the scope of RN licensure
  • Promote a culture of safety, teamwork, continuous improvement, and patient-centered care
  • Monitor quality metrics, patient satisfaction, and operational performance indicators while implementing improvement initiatives
  • Demonstrate professionalism and adherence to UNC Health Appalachian’s Mission, Vision, and Values
QualificationsEducation
  • Graduate of an accredited nursing program required
  • Master of Science in Nursing (MSN) preferred
Experience
  • Minimum of two years of experience as a Registered Nurse preferred
  • Previous healthcare experience in an acute care or clinic setting required
  • Minimum of one year of prior nursing leadership experience required (Charge Nurse, Supervisor, or similar leadership role)
Licenses/Certifications
  • Current Registered Nurse (RN) licensure in North Carolina required
  • Basic Life Support (BLS) certification from the American Heart Association required at hire
  • Additional required certifications must be obtained within one year of hire date
  • Advanced Cardiac Life Support (ACLS) preferred
  • Pediatric Advanced Life Support (PALS) preferred
  • Emergency Nurse Pediatric Course (ENPC) preferred
  • Trauma Nursing Core Course (TNCC) preferred
  • NIH Stroke Scale (NIHSS) certification required within one year of hire
Skills & Abilities
  • Strong leadership, communication, and interpersonal skills
  • Ability to deliver safe and effective patient care within the scope of RN licensure and organizational policies
  • Knowledge of emergency and acute care nursing operations
  • Ability to effectively manage teams, workflows, and departmental priorities
  • Strong critical thinking, problem-solving, and decision-making abilities
  • Commitment to exceptional customer service and patient-centered care
Physical & Work Environment
  • Frequent standing, walking, bending, lifting, and patient mobilization throughout shifts
  • Frequent lifting, carrying, pushing, and pulling greater than 50 lbs
  • Frequent hand, finger, and wrist repetition with moderate dexterity
  • Exposure to bloodborne pathogens, electrical/mechanical equipment, chemicals, and emergency situations
  • Subject to irregular schedules including days, evenings, nights, weekends, holidays, and emergency response situations
  • Frequent close eye work and exposure to soft voices in clinical environments
  • Occasional exposure to ionizing/non-ionizing radiation including x-ray and microwave exposure
What Sets Us Apart
  • Leadership Impact: Lead high-performing clinical teams while shaping patient care operations across critical departments
  • Professional Growth: Expand your leadership expertise through continuing education, certification support, and advancement opportunities
  • Mission-Driven Culture: Join a healthcare system focused on compassion, quality, accountability, and innovation
  • Community & Lifestyle: Enjoy the beauty and lifestyle of Boone, North Carolina — known for outdoor recreation, mountain living, and vibrant community culture

Ready to lead with purpose and make a lasting impact in healthcare operations?
Apply today to join UNC Health Appalachian and help deliver exceptional care to the communities we proudly serve.

About UNC Health Appalachian
It's official - UNC Health Appalachian earned an "A" in the fall 2023 Leapfrog Patient Safety Grades! UNC Health Appalachian, the leader for healthcare in the High Country, comprises three hospitals, 13 medical practices, Seby B. Jones Regional Cancer Center, The Rehabilitation Center, and Appalachian Regional Healthcare Foundation. UNC Health Appalachian stays committed to promoting health in the High Country, enhancing quality of life, and simply “making life better.” 

About UNC Health 
UNC Health is a state entity and an affiliated enterprise of the University of North Carolina system, comprised of 14 hospitals, 18 hospital campuses and more than 500 clinics along with the clinical patient care programs of the UNC School of Medicine (SOM). It exists to improve the health and well-being of North Carolinians and others we serve and to further the teaching mission of the University of North Carolina SOM. Over the past three years, UNC Health has provided more than $400 million in uncompensated or charity care to the citizens of North Carolina. Our hospitals have received numerous awards and recognition for quality care, patient safety and the overall patient experience. For more information, please visit unchealth.org. 

UNC Health Appalachian embraces diversity and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, or any other protected status. We value a workforce that reflects a variety of backgrounds and perspectives, as it enhances our ability to provide outstanding care. We welcome and encourage applications from candidates of all backgrounds and experiences. UNC Health Appalachian is committed to providing a fair and inclusive hiring process and a workplace where all team members feel respected and empowered. If you require accommodations during the application process, please contact us. 

Employment at UNC Health Appalachian is contingent upon successful completion of a background and drug screen. For accommodations or additional information, contact arhsrecruitment@unchealth.unc.edu. 

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