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Clinical Operation Manager Jobs in Raleigh, NC (NOW HIRING)

AMC Health

VP, Clinical Operations

Raleigh, NC · On-site

Data & Performance Management * Establish operational metrics and KPIs supporting clinical program performance. * Monitor performance data to identify trends and opportunities for improvement.

Aerogen Ltd

Clinical Trial Manager

Morrisville, NC · On-site

... Operations and escalate potential quality risks in a timely manner working closely with Clinical ... • Manage CRAs assigned to clinical trials and activities related to site qualification ...

IQVIA, Inc.

Clinical Trial Lead

Durham, NC · On-site

An education as a physician would be a plus. • Minimum of 5 years (or 10 years for Senior CTL role) of global clinical operations management experience, preferable within a global CRO environment ...

IQVIA

Clinical Trial Lead

Durham, NC · On-site +1

Manage and mentor clinical operations staff, including performance appraisals, development planning, and resolution of employee relations issues. Provide coaching on project planning, risk management ...

IQVIA

Clinical Trial Lead

Durham, NC · On-site +1

Manage and mentor clinical operations staff, including performance appraisals, development planning, and resolution of employee relations issues. Provide coaching on project planning, risk management ...

Experis

Clinical Trial Manager

Chapel Hill, NC · On-site

As a Clinical Trial Manager, you will be an integral part of the Clinical Operations department supporting project teams. The ideal candidate will demonstrate strong leadership, excellent ...

Adecco

Clinical Trials Manager- Remote

Chapel Hill, NC · Remote

$62 - $64.73/hr

Manage clinical operational and quality activities for assigned studies in compliance with ICH/GCP and applicable regulations . * Develop and maintain clinical tools, monitoring plans, guidelines ...

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All JobsClinical Operation JobsClinical Operation Manager JobsClinical Operation Manager Jobs in Raleigh, NC

Clinical Operation Manager information

See Raleigh, NC salary details

$30.9K

$86.6K

$164.7K

How much do clinical operation manager jobs pay per year?

As of Aug 25, 2026, the average yearly pay for clinical operation manager in Raleigh, NC is $86,560.00, according to ZipRecruiter salary data. Most workers in this role earn between $64,000.00 and $100,200.00 per year, depending on experience, location, and employer.

What is a clinical operation manager?

Clinical Operation Managers are professionals responsible for overseeing the daily operations of clinical research sites, medical facilities, or departments. They ensure that clinical trials or healthcare services are conducted efficiently, comply with regulations, and meet quality standards. Their duties often include supervising staff, managing budgets, implementing policies, and coordinating between various teams. Clinical Operation Managers play a crucial role in ensuring that patient care and research activities run smoothly and effectively.

What are the key skills and qualifications needed to thrive as a clinical operation manager?

To thrive as a Clinical Operation Manager, you need expertise in clinical project management, regulatory compliance, and a background in healthcare or life sciences, often supported by a relevant degree. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) tools, and certifications such as PMP or Six Sigma are commonly required. Strong leadership, problem-solving abilities, and excellent communication skills set top performers apart in this role. These competencies are essential for ensuring efficient clinical operations, maintaining regulatory standards, and leading teams to deliver successful trial outcomes.

What are some common challenges clinical operation managers face when coordinating multi-site clinical trials?

Clinical Operation Managers often encounter challenges such as ensuring consistent protocol adherence across all sites, managing communication among geographically dispersed teams, and maintaining timelines despite unexpected delays. They must also address regulatory differences between sites and troubleshoot issues related to patient recruitment and data collection. Success in this role requires strong organizational skills, adaptability, and effective collaboration with investigators, coordinators, and regulatory personnel.

What is the difference between Clinical Operation Manager vs Clinical Research Coordinator?

AspectClinical Operation ManagerClinical Research Coordinator
CredentialsBachelor's degree in health sciences, life sciences, or related field; often with project management certificationsBachelor's degree in health sciences, nursing, or related field; often with research-specific training
Work EnvironmentOversees multiple clinical trials, manages teams, and ensures compliance at a departmental levelCoordinates daily activities of clinical trials, interacts directly with participants and investigators
Employer & IndustryPharmaceutical companies, biotech firms, hospitals, research institutionsResearch sites, hospitals, academic institutions, contract research organizations

The Clinical Operation Manager focuses on overseeing clinical trial operations, managing teams, and ensuring compliance across projects. In contrast, the Clinical Research Coordinator handles the day-to-day activities of specific trials, working closely with participants and investigators. Both roles require relevant healthcare or science credentials, but their scope and responsibilities differ significantly.

What are popular job titles related to Clinical Operation Manager jobs in Raleigh, NC?

For Clinical Operation Manager jobs in Raleigh, NC, the most frequently searched job titles are:

What job categories do people searching Clinical Operation Manager jobs in Raleigh, NC look for?

The top searched job categories for Clinical Operation Manager jobs in Raleigh, NC are:

What cities near Raleigh, NC are hiring for Clinical Operation Manager jobs?

Cities near Raleigh, NC with the most Clinical Operation Manager job openings:

Clinical Operation Manager jobs near you
Infographic showing various Clinical Operation Manager job openings in Raleigh, NC as of August 2026, with employment types broken down into 88% Full Time, 10% Part Time, and 2% Contract. Highlights an 79% Physical, 2% Hybrid, and 19% Remote job distribution, with an average salary of $86,560 per year, or $41.6 per hour.

Clinical Operations Manager

Chapel Hill, NC • On-site

UNC-Chapel Hill
Colleges, Universities, and Professional Schools • 10K+ employees

7.5

Company rating: 7.5 out of 10

Based on 48 frontline employees who took The Breakroom Quiz

314th of 622 rated colleges and universities

People enjoy working here

Good employer

Recommended by students

Learn more about UNC-Chapel Hillexternal

Full-time

Medical, Life, Retirement, PTO

Re-posted 25 days ago

Job description

Posting Information
Department LCCC - Clinical Trials-426806 Career Area Research Professionals Posting Open Date 06/01/2026 Application Deadline 09/03/2026 Open Until Filled No Position Type Permanent Staff (EHRA NF) Working Title Clinical Operations Manager Appointment Type EHRA Non-Faculty Position Number 20076534, 20010901 Vacancy ID NF0009791 Full Time/Part Time Full-Time Permanent FTE 1 Hours per week 40 Position Location North Carolina, US Hiring Range Salary commensurate with qualifications Proposed Start Date 06/29/2026
Position Information
Be a Tar Heel!
A global higher education leader in innovative teaching, research and public service, the University of North Carolina at Chapel Hill consistently ranks as one of the nation's top public universities. Known for its beautiful campus, world-class medical care, commitment to the arts and top athletic programs, Carolina is an ideal place to teach, work and learn.
One of the best college towns and best places to live in the United States, Chapel Hill has diverse social, cultural, recreation and professional opportunities that span the campus and community.
University employees can choose from a wide range of professional training opportunities for career growth, skill development and lifelong learning and enjoy exclusive perks for numerous retail, restaurant and performing arts discounts, savings on local child care centers and special rates on select campus events. UNC-Chapel Hill offers full-time employees a comprehensive benefits package, paid leave, and a variety of health, life and retirement plans and additional programs that support a healthy work/life balance.
Primary Purpose of Organizational Unit
Our mission is to improve the health and well-being of North Carolinians and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education and research.
Patient care: We promote health and provide superb clinical care while maintaining our strong tradition of reaching underserved populations and reducing health disparities across North Carolina and beyond.
Education: We prepare tomorrow`s healthcare professionals and biomedical researchers from all backgrounds by facilitating learning within innovative and integrated curricula and team-oriented interprofessional education to ensure a highly skilled workforce.
Research: We develop and support a rich array of outstanding health sciences research programs, centers and resources. We provide infrastructure and opportunities for collaboration among disciplines throughout and beyond our university to support outstanding research. We foster programs in the areas of basic, translational, mechanistic and population research.
Position Summary
The Clinical Operations Manager provides oversight and management of a large number of clinical research staff to ensure safe, compliant, efficient, and effective conduct of oncology clinical trials. This position provides expert level knowledge in clinical trial practices and regulations. This position works under the direct supervision of the Assistant Director of Clinical Research Operations to ensure safe implementation of oncology clinical trials. The Clinical Operations Manager manages clinical research staff assigned to various disease teams within the Clinical Protocol Office (CPO) providing daily management/supervision, resource and effort allocation, overseeing research compliance and data integrity, and assisting in strategic planning and operational support. This position creates and champions a collaborative and positive relationship dynamic with internal staff and external agencies/organizations.
Minimum Education and Experience Requirements
Master's degree in a discipline related to the field assigned; or Bachelor's degree in a discipline related to the field assigned and two years of research/analysis, preferably with one year in a supervisory role; or equivalent combination of training and experience. All degrees must be received from appropriately accredited institutions.
Required Qualifications, Competencies, and Experience
Advanced knowledge of ICH GCP, Federal Regulations and Guidelines and ability to follow established regulations, procedures, and protocols; clinical research experience; Experience in interviewing/hiring process and performance management; Possess strong decision-making skills and the ability to problem solve and troubleshoot issues; Strong organizational skills with the ability to manage large volumes of information; High level of accuracy and attention to detail; High level of comfort with technology; Strong computer skills; Ability to gather data and document procedures; Ability to plan work and coordinate multiple projects; Ability to contribute to preparation and delivery of reports, trainings and SOPs; Customer oriented and ability to work within, build and lead a team; Exceptional interpersonal skills and excellent verbal and written communication skills in daily interactions with the ability to interpret and apply UNC policies and federal, state, and local regulations; Ability to work on evenings, weekends and/or holidays occasionally required.
Preferred Qualifications, Competencies, and Experience
Therapeutic clinical trial coordination experience involving drugs and/or devices, to include work in oncology;
SOCRA/ACRP certification;
Supervisory experience;
Experience in Phase I, II, and III clinical research;
Experience navigating medical records and data extraction;
Experience leading a large team.
Special Physical/Mental Requirements Campus Security Authority Responsibilities

Not Applicable.

Special Instructions Quick Link https://unc.peopleadmin.com/postings/319826
Posting Contact Information
Department Contact Name and Title Gretchen Harrison Department Contact Telephone or Email gretchen_harrison@med.unc.edu Office of Human Resources Contact Information

If you experience any problems accessing the system or have questions about the application process, please contact the Office of Human Resources at (919) 843-2300 or send an email to employment@unc.edu
Please note: The Office of Human Resources will not be able to provide specific updates regarding position or application status.

Equal Opportunity Employer Statement
The University is an equal opportunity employer and welcomes all to apply without regard to age, color, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, or sexual orientation. We encourage all qualified applicants to apply, including protected veterans and individuals with disabilities.
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About University of North Carolina at Chapel Hill

Sourced by ZipRecruiter

The University of North Carolina at Chapel Hill (UNC-Chapel Hill), located in Chapel Hill, NC, US, is renowned for being one of the leading research institutes in the world. Operating within the education industry, this public research university offers a broad range of undergraduate, graduate, and professional programs across various disciplines. UNC-Chapel Hill was chartered in 1789 and has maintained its legacy of academic excellence and innovative research for more than two centuries. The institution operates under the core values of excellence, innovation, engagement, accessibility, diversity, and inclusivity. Their mission is to serve the people of North Carolina and the United States by teaching a diverse community of students to become the next generation of leaders.

Industry

Colleges, universities, and professional schools

Company size

10,000+ Employees

Headquarters location

Chapel Hill, NC, US

Year founded

1789

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