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Director Clinical Operations Jobs in Raleigh, NC

Cellectis

Director, Clinical Quality Assurance

Raleigh, NC · On-site

$190K - $2M/yr

This role provides strategic and operational quality leadership in alignment with other departments ... The Director, Clinical Quality Assurance, will manage activities and projects based on short-term ...

Red Oak Recovery Center

Clinical Director

Durham, NC · Remote

$90K - $100K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

  • PTO

We are seeking a Clinical Director to add to our dynamic team. This position will support our ... Develop and implement policies and procedures to improve clinical operations and enhance patient ...

Fortrea

Director, Clinical FSP Delivery

Durham, NC · On-site

Fortrea's is hiring a Director, Clinical FSP Delivery. We are seeking a strategic client leader ... Must have an excellent understanding of clinical operations within the FSP Delivery model. This ...

Pair ABA

Clinical Director

Clayton, NC · On-site

$120K - $140K/yr

Children ages 2-16 Years in Operation: Founded in 2025 What You'll Actually Be Doing (aka no ... Caseload size: 7-10 clients (This is a hands-on Clinical Director position. You'll initially ...

New

Jobtailor

Senior Director, Clinical Development

Cary, NC · On-site

$120 - $190/hr

Manage Key Opinion Leader and Medical Advisory Board interactions * Assist Clinical Operations with supervision of activities of contract research organizations by reviewing key study plans and ...

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All JobsClinical Operations JobsDirector Clinical Operations JobsDirector Clinical Operations Jobs in Raleigh, NC

Director Clinical Operations information

See Raleigh, NC salary details

$58.3K

$141.9K

$274.6K

How much do director clinical operations jobs pay per year?

As of Aug 14, 2026, the average yearly pay for director clinical operations in Raleigh, NC is $141,894.00, according to ZipRecruiter salary data. Most workers in this role earn between $99,200.00 and $168,700.00 per year, depending on experience, location, and employer.

What does a director of clinical operations do?

A director of clinical operations manages the daily operations of a healthcare facility or a specific department within a clinic or hospital. As a director of clinical operations, your responsibilities include scheduling staff to ensure proper coverage of patients and overseeing the productivity of your team to meet the organization's expectations. You define policies and procedures, facilitating further training when necessary. The director of clinical operations must also assess the performance of the medical team under your supervision regularly and mainstream processes when possible. Medical device manufacturers and pharmaceutical companies often hire a director of clinical operations to oversee research, lab, and testing operations.

What are the key skills and qualifications needed to thrive as a director of clinical operations?

To thrive as a Director of Clinical Operations, you need a robust background in clinical management, regulatory compliance, and healthcare administration, often supported by a relevant degree and substantial leadership experience. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) tools, and certifications like PMP or CCRA are commonly required. Exceptional leadership, strategic thinking, and communication skills help drive teams, manage stakeholders, and oversee complex projects. These skills are critical for ensuring clinical programs run efficiently, meet regulatory standards, and deliver high-quality patient outcomes.

What is the difference between Director Clinical Operations vs Clinical Project Manager?

AspectDirector Clinical OperationsClinical Project Manager
CredentialsTypically requires advanced degrees (e.g., MS, PhD) and extensive industry experienceUsually holds a bachelor's or master's degree in a related field, with relevant project management certifications
Work EnvironmentOversees multiple projects and teams across departments, strategic planningManages individual clinical trials, coordinates project activities, and timelines
Employer & Industry UsageUsed in pharmaceutical, biotech, and healthcare companies for senior leadership rolesCommonly employed in clinical research organizations and pharmaceutical companies for trial management

The main difference is that the Director Clinical Operations focuses on strategic oversight and leadership across multiple clinical trials, while the Clinical Project Manager handles the day-to-day management of specific clinical studies. Both roles require strong industry knowledge, but the director position involves broader responsibilities and higher-level decision-making.

What does a director of clinical operations do?

A Director of Clinical Operations is responsible for overseeing the day-to-day management and strategic direction of clinical trials and research activities within healthcare organizations or pharmaceutical companies. They ensure that clinical studies are conducted efficiently, ethically, and in compliance with regulatory requirements. This role involves supervising teams, managing budgets, developing protocols, and liaising with stakeholders to ensure successful trial outcomes. Directors of Clinical Operations play a crucial role in bringing new medical treatments to market by ensuring studies run smoothly from start to finish.

How does a director of clinical operations typically collaborate with cross-functional teams to ensure successful clinical trial execution?

A Director of Clinical Operations regularly collaborates with cross-functional teams such as regulatory affairs, data management, medical affairs, and biostatistics to ensure clinical trials are executed on time, within budget, and in compliance with regulations. This role involves leading team meetings, aligning project timelines, and facilitating communication between internal stakeholders and external partners like CROs and vendors. Strong coordination skills are essential, as the Director must balance diverse priorities and resolve any operational issues that arise, ensuring all teams work toward shared objectives.
More about Director Clinical Operations jobs

What are the most commonly searched types of Clinical Operations jobs in Raleigh, NC?

The most popular types of Clinical Operations jobs in Raleigh, NC are:

What job categories do people searching Director Clinical Operations jobs in Raleigh, NC look for?

The top searched job categories for Director Clinical Operations jobs in Raleigh, NC are:

What cities near Raleigh, NC are hiring for Director Clinical Operations jobs?

Cities near Raleigh, NC with the most Director Clinical Operations job openings:

Director Clinical Operations jobs near you
Infographic showing various Director Clinical Operations job openings in Raleigh, NC as of August 2026, with employment types broken down into 82% Full Time, 14% Part Time, 1% Temporary, and 3% Contract. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution, with an average salary of $141,894 per year, or $68.2 per hour.

Director of Clinical Operations

North Carolina Retina Associates

Raleigh, NC • On-site

Full-time

Re-posted 12 days ago

Job description

SUMMARY:
This position is responsible for providing strategic leadership and direction of the overall clinical operations for the Practice.  The Director will work closely with the physician leadership and practice leadership to continuously improve the patient experience and refine the department strategic plan.  The Director is responsible for creating an operating plan that executes the organizational plan. This requires coordination with practice leadership to execute the plan.  This position has direct management responsibility for the clinical managers.  

DUTIES & RESPONSIBILITIES:
  • Lead and optimize clinical processes.
  • Partner with physicians on clinical practices and protocols into operational improvements specific to a given doctor, location or clinic process.
  • Leads and mentors clinical managers.
  • Leads and supports the professional development of clinical managers and their teams.
  •  Controls and steadily improves the entire department’s use of systems, processes and resources to better serve the patients, physicians and the practice.
  • Analyzes operations to improve systems and processes that improve performance.
  • Visible in clinics to support and assess operations.
  • Supports integration during mergers and acquisition; and the opening of new offices.
  • Collaborates with the practice senior leadership.
  • Maintain strict confidentiality with PHI, understands and adheres to practice policies and procedures.
  • Performs other duties as assigned.
QUALIFICATIONS:
  • Bachelor's degree in Healthcare Administration, Business Administration, Finance, or a related field.
  • Minimum of 5 years of experience in healthcare management, with demonstrated progression of responsibilities. Ophthalmology or Retina experience is preferred.
  • In-depth knowledge of healthcare practices, and regulatory requirements. Retina experience preferred.
  • Strong leadership and team management skills, with the ability to motivate and develop a high-performing team.
  • Excellent analytical skills and the ability to interpret data.
  • Proficiency with medical records software.
  • Strong communication and interpersonal skills, with the ability to collaborate effectively with internal and external stakeholders.
  • Preferred Certifications: COA, COT, OSC.
ESSENTIAL JOB FUNCTIONS:
  • Prolonged sitting, standing, bending, stooping, and stretching.  
  • Position requires frequent driving and travel to clinic sites in NC, as well as off-site conferences and meetings. Approximately 75% travel.
  • Must have the ability to assist with patient mobility including pushing, pulling or lifting patients in and out of chairs or stools. 
  • Frequent lifting of up to 5 lbs., occasional lifting of up to 25 lbs.  
  • Requires normal range of hearing and eyesight to perform daily tasks. 
  • Must be able to operate a computer keyboard, mouse, phone, e-mail, copy/fax machine.