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Director Clinical Operations Jobs in Raleigh, NC

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Manager Clinical Operations

Durham, NC

Your focus will be on coordinating clinical operations delivery, resolving issues, and developing ... Minimum of 3 years of direct experience in biosample management is required * Proficiency in ...

IQVIA, Inc.

Manager, Clinical Operations

Durham, NC · On-site

$86K - $216K/yr

Responsibilities include planning, assigning, and directing work, assessing performance and guiding ... by clinical operations management. • May collaborate with other clinical teams and other ...

IQVIA

Manager, Clinical Operations

Durham, NC

$86K - $216K/yr

Responsibilities include planning, assigning, and directing work, assessing performance and guiding ... clinical operations management. May collaborate with other clinical teams and other functional ...

IQVIA

Manager, Clinical Operations

Durham, NC

$86K - $216K/yr

Responsibilities include planning, assigning, and directing work, assessing performance and guiding ... clinical operations management. May collaborate with other clinical teams and other functional ...

IQVIA, Inc.

Manager, Clinical Operations

Durham, NC · On-site

$86K - $216K/yr

Responsibilities include planning, assigning, and directing work, assessing performance and guiding ... by clinical operations management. • May collaborate with other clinical teams and other ...

IQVIA

Manager, Clinical Operations

Durham, NC

$86K - $216K/yr

Responsibilities include planning, assigning, and directing work, assessing performance and guiding ... clinical operations management. May collaborate with other clinical teams and other functional ...

IQVIA

Manager, Clinical Operations

Durham, NC

$86K - $216K/yr

Responsibilities include planning, assigning, and directing work, assessing performance and guiding ... clinical operations management. May collaborate with other clinical teams and other functional ...

UNC HEALTH

Director Clinical Research

Raleigh, NC · On-site

Provides strategic, operational, regulatory, financial, and program leadership for the Heart & Vascular clinical research portfolio. Directs program-level planning, workforce development, and ...

NCBiotech

Director, Clinical Quality Assurance

Raleigh, NC · On-site

$200 - $250/hr

This role provides strategic and operational quality leadership in alignment with other departments ... The Director, Clinical Quality Assurance, will manage activities and projects based on short-term ...

Cellectis

Director, Clinical Quality Assurance

Raleigh, NC · On-site

$190K - $2M/yr

This role provides strategic and operational quality leadership in alignment with other departments ... The Director, Clinical Quality Assurance, will manage activities and projects based on short-term ...

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All JobsClinical Operations JobsDirector Clinical Operations JobsDirector Clinical Operations Jobs in Raleigh, NC

Director Clinical Operations information

See Raleigh, NC salary details

$58.3K

$141.9K

$274.6K

How much do director clinical operations jobs pay per year?

As of Sep 7, 2026, the average yearly pay for director clinical operations in Raleigh, NC is $141,886.00, according to ZipRecruiter salary data. Most workers in this role earn between $99,100.00 and $168,600.00 per year, depending on experience, location, and employer.

What does a director of clinical operations do?

A director of clinical operations manages the daily operations of a healthcare facility or a specific department within a clinic or hospital. As a director of clinical operations, your responsibilities include scheduling staff to ensure proper coverage of patients and overseeing the productivity of your team to meet the organization's expectations. You define policies and procedures, facilitating further training when necessary. The director of clinical operations must also assess the performance of the medical team under your supervision regularly and mainstream processes when possible. Medical device manufacturers and pharmaceutical companies often hire a director of clinical operations to oversee research, lab, and testing operations.

What does a director of clinical operations do?

A Director of Clinical Operations is responsible for overseeing the day-to-day management and strategic direction of clinical trials and research activities within healthcare organizations or pharmaceutical companies. They ensure that clinical studies are conducted efficiently, ethically, and in compliance with regulatory requirements. This role involves supervising teams, managing budgets, developing protocols, and liaising with stakeholders to ensure successful trial outcomes. Directors of Clinical Operations play a crucial role in bringing new medical treatments to market by ensuring studies run smoothly from start to finish.

What are the key skills and qualifications needed to thrive as a director of clinical operations?

To thrive as a Director of Clinical Operations, you need a robust background in clinical management, regulatory compliance, and healthcare administration, often supported by a relevant degree and substantial leadership experience. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) tools, and certifications like PMP or CCRA are commonly required. Exceptional leadership, strategic thinking, and communication skills help drive teams, manage stakeholders, and oversee complex projects. These skills are critical for ensuring clinical programs run efficiently, meet regulatory standards, and deliver high-quality patient outcomes.

How does a director of clinical operations typically collaborate with cross-functional teams to ensure successful clinical trial execution?

A Director of Clinical Operations regularly collaborates with cross-functional teams such as regulatory affairs, data management, medical affairs, and biostatistics to ensure clinical trials are executed on time, within budget, and in compliance with regulations. This role involves leading team meetings, aligning project timelines, and facilitating communication between internal stakeholders and external partners like CROs and vendors. Strong coordination skills are essential, as the Director must balance diverse priorities and resolve any operational issues that arise, ensuring all teams work toward shared objectives.

What is the difference between Director Clinical Operations vs Clinical Project Manager?

AspectDirector Clinical OperationsClinical Project Manager
CredentialsTypically requires advanced degrees (e.g., MS, PhD) and extensive industry experienceUsually holds a bachelor's or master's degree in a related field, with relevant project management certifications
Work EnvironmentOversees multiple projects and teams across departments, strategic planningManages individual clinical trials, coordinates project activities, and timelines
Employer & Industry UsageUsed in pharmaceutical, biotech, and healthcare companies for senior leadership rolesCommonly employed in clinical research organizations and pharmaceutical companies for trial management

The main difference is that the Director Clinical Operations focuses on strategic oversight and leadership across multiple clinical trials, while the Clinical Project Manager handles the day-to-day management of specific clinical studies. Both roles require strong industry knowledge, but the director position involves broader responsibilities and higher-level decision-making.

Is a director of clinical operations a high position?

A director of clinical operations is a senior leadership role responsible for overseeing clinical trial activities, managing teams, and ensuring regulatory compliance. It is considered a high-level position within the healthcare and pharmaceutical industries, often requiring extensive experience and strategic skills.
More about Director Clinical Operations jobs

What are the most commonly searched types of Clinical Operations jobs in Raleigh, NC?

The most popular types of Clinical Operations jobs in Raleigh, NC are:

What are popular job titles related to Director Clinical Operations jobs in Raleigh, NC?

For Director Clinical Operations jobs in Raleigh, NC, the most frequently searched job titles are:

What job categories do people searching Director Clinical Operations jobs in Raleigh, NC look for?

The top searched job categories for Director Clinical Operations jobs in Raleigh, NC are:

What cities near Raleigh, NC are hiring for Director Clinical Operations jobs?

Cities near Raleigh, NC with the most Director Clinical Operations job openings:

Director Clinical Operations jobs near you
Infographic showing various Director Clinical Operations job openings in Raleigh, NC as of August 2026, with employment types broken down into 92% Full Time, 5% Part Time, and 3% Contract. Highlights an 90% In-person, 3% Hybrid, and 7% Remote job distribution, with an average salary of $141,886 per year, or $68.2 per hour.

Medical Director and Vice Chief of Clinical Operations, Memory Disorders Clinics

Duke Health

Durham, NC • On-site

Full-time

Medical, Retirement

Re-posted 27 days ago

Duke Health rating

7.2

Company rating: 7.2 out of 10

Based on 256 frontline employees who took The Breakroom Quiz

346th of 898 rated healthcare providers

Job description

Duke Neurology seeks a board certified Neurologist with interest in Memory Disorders or Behavioral Neurologist with focus in clinical care to join its expanding outpatient neurology practice
The Department of Neurology at Duke University School of Medicine seeks a board certified Neurologist with interest in Memory Disorders or Behavioral Neurologist with focus in clinical care to join its expanding outpatient neurology practice in the rapidly growing Raleigh-Durham, NC area and fill the role of Medical Director/Vice Chief of Clinical Operations of the Memory Disorders Clinics.
  • The hired physician will provide patient care in Duke Neurology Clinics, with a primary focus on Memory Disorders and the option to include a portion of general neurology, as desired.
  • This position is an outpatient-only clinical position, as a team of Duke Neurohospitalists handle all inpatient coverage.
  • Successful candidate will complete all duties of Medical Director including overseeing clinical operations, clinic access, management of clinic personnel and clinical/research continuity.
  • Teaching role includes preceptorship of medical students, neurology residents and fellows from multiple disciplines with an interest in Memory Disorders.

Duke Health offers a robust compensation plan that rewards clinical productivity and academic excellence. Salary and faculty title will be commensurate with training, experience, and the focus of the role. Faculty members enjoy Duke benefits including retirement planning, health insurance, CME, relocation, and college tuition assistance for dependent children.
Learn more about the Triangle
Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, (including pregnancy and pregnancy related conditions), sexual orientation, or military status.
Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.
PLEASE NOTE: To be considered for this position, please attach your CV, select SUBMIT APPLICATION, and complete the application questions.

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