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Clinical Operation Manager Jobs in Raleigh, NC (NOW HIRING)

Icon plc

Clinical Operations Specialist

Raleigh, NC · On-site

Clinical Operations Specialist ICON is a global healthcare intelligence and clinical research ... Managing and maintaining comprehensive and accurate records of regulatory submissions, approvals ...

Icon plc

Clinical Operations Specialist

Raleigh, NC · On-site

Clinical Operations Specialist ICON is a global healthcare intelligence and clinical research ... Managing and maintaining comprehensive and accurate records of regulatory submissions, approvals ...

Doist

Clinical Study Design Manager

Morrisville, NC · On-site

$125 - $150/hr

Partner with Clinical Operations and Data Management to provide early strategic input on protocol design and execute post-production changes. * Build and maintain effective working relationships with ...

IQVIA, Inc.

Clinical Lead- CVRM/MASH

Durham, NC · On-site

Manage the clinical team at project level to successfully deliver the project through the establishment of high-quality operational plans and guidance and project related trainings. • Conduct ...

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Clinical Operation Manager information

See Raleigh, NC salary details

$34K

$95.3K

$181.3K

How much do clinical operation manager jobs pay per year?

As of Sep 8, 2026, the average yearly pay for clinical operation manager in Raleigh, NC is $95,296.00, according to ZipRecruiter salary data. Most workers in this role earn between $70,500.00 and $110,300.00 per year, depending on experience, location, and employer.

What is a clinical operation manager?

Clinical Operation Managers are professionals responsible for overseeing the daily operations of clinical research sites, medical facilities, or departments. They ensure that clinical trials or healthcare services are conducted efficiently, comply with regulations, and meet quality standards. Their duties often include supervising staff, managing budgets, implementing policies, and coordinating between various teams. Clinical Operation Managers play a crucial role in ensuring that patient care and research activities run smoothly and effectively.

What are the key skills and qualifications needed to thrive as a clinical operation manager?

To thrive as a Clinical Operation Manager, you need expertise in clinical project management, regulatory compliance, and a background in healthcare or life sciences, often supported by a relevant degree. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) tools, and certifications such as PMP or Six Sigma are commonly required. Strong leadership, problem-solving abilities, and excellent communication skills set top performers apart in this role. These competencies are essential for ensuring efficient clinical operations, maintaining regulatory standards, and leading teams to deliver successful trial outcomes.

What are some common challenges clinical operation managers face when coordinating multi-site clinical trials?

Clinical Operation Managers often encounter challenges such as ensuring consistent protocol adherence across all sites, managing communication among geographically dispersed teams, and maintaining timelines despite unexpected delays. They must also address regulatory differences between sites and troubleshoot issues related to patient recruitment and data collection. Success in this role requires strong organizational skills, adaptability, and effective collaboration with investigators, coordinators, and regulatory personnel.

What is the difference between Clinical Operation Manager vs Clinical Research Coordinator?

AspectClinical Operation ManagerClinical Research Coordinator
CredentialsBachelor's degree in health sciences, life sciences, or related field; often with project management certificationsBachelor's degree in health sciences, nursing, or related field; often with research-specific training
Work EnvironmentOversees multiple clinical trials, manages teams, and ensures compliance at a departmental levelCoordinates daily activities of clinical trials, interacts directly with participants and investigators
Employer & IndustryPharmaceutical companies, biotech firms, hospitals, research institutionsResearch sites, hospitals, academic institutions, contract research organizations

The Clinical Operation Manager focuses on overseeing clinical trial operations, managing teams, and ensuring compliance across projects. In contrast, the Clinical Research Coordinator handles the day-to-day activities of specific trials, working closely with participants and investigators. Both roles require relevant healthcare or science credentials, but their scope and responsibilities differ significantly.

What are popular job titles related to Clinical Operation Manager jobs in Raleigh, NC?

For Clinical Operation Manager jobs in Raleigh, NC, the most frequently searched job titles are:

What job categories do people searching Clinical Operation Manager jobs in Raleigh, NC look for?

The top searched job categories for Clinical Operation Manager jobs in Raleigh, NC are:

What cities near Raleigh, NC are hiring for Clinical Operation Manager jobs?

Cities near Raleigh, NC with the most Clinical Operation Manager job openings:

Clinical Operation Manager jobs near you
Infographic showing various Clinical Operation Manager job openings in Raleigh, NC as of August 2026, with employment types broken down into 86% Full Time, 13% Part Time, and 1% Contract. Highlights an 88% Physical, 2% Hybrid, and 10% Remote job distribution, with an average salary of $95,296 per year, or $45.8 per hour.

Clinical Operations Specialist

Icon plc

Raleigh, NC • On-site

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 24 days ago

Job description

Clinical Operations Specialist

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.


As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.


As a Study Start Up Associate II at ICON, you will lead the initiation of clinical trials, ensuring compliance with regulatory requirements, and contribute to the advancement of innovative treatments and therapies.

What You Will Do:

You will contribute to site start-up and activation activities, taking responsibility for your deliverables and working collaboratively.
Key responsibilities include:

  • Leading the preparation and submission of regulatory documents, including clinical trial applications, ethics committee submissions, and regulatory agency communications.
  • Coordinating and liaising with internal and external stakeholders to obtain necessary approvals and authorizations for study initiation.
  • Managing and maintaining comprehensive and accurate records of regulatory submissions, approvals, and correspondence
  • Providing guidance and support to study teams on regulatory requirements and best practices for study start-up activities.
  • Participating in process improvement initiatives to streamline study start-up processes and enhance efficiency.

Your Profile:

You will bring relevant site start-up and activation experience, along with the following qualifications and skills.
Required qualifications and experience:

  • Bachelor's degree in life sciences or a related field.
  • Minimum of 2 years of experience in clinical research or regulatory affairs, with specific experience in study start-up activities.
  • Strong understanding of regulatory requirements and guidelines for clinical trials, including ICH-GCP and local regulatory requirements.
  • Excellent organizational and project management skills, with the ability to prioritize and manage multiple tasks simultaneously.
  • Excellent communication and interpersonal skills, with the ability to collaborate effectively with cross-functional teams.
  • Willingness to travel as required (approximately 5%)

Employment with ICON is contingent upon having the legal right to work in the country where the role is based.


Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.


Benefits may include:

  • Competitive base salary and performance related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.


Visit our careers site to read more about the benefits ICON offers.


Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.


If you require reasonable accommodations during the recruitment process, please let us know or submit a requesthere.

Are you a current ICON Employee? Please click here to apply

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