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Clinical Operation Manager Jobs in Raleigh, NC (NOW HIRING)

IQVIA, Inc.

Clinical Project Manager- IVD

Durham, NC · On-site

$93K - $232K/yr

Overseeing planning and operational aspects of companion diagnostics studies sponsored by Pharma ... Collaborating across Clinical Operations and other functions to develop and implementing best ...

IQVIA

Clinical Project Manager- IVD

Durham, NC · On-site

$93K - $232K/yr

Overseeing planning and operational aspects of companion diagnostics studies sponsored by Pharma ... Collaborating across Clinical Operations and other functions to develop and implementing best ...

IQVIA

Clinical Project Manager- IVD

Durham, NC · On-site

$93K - $232K/yr

Overseeing planning and operational aspects of companion diagnostics studies sponsored by Pharma ... Collaborating across Clinical Operations and other functions to develop and implementing best ...

Icon plc

Clinical Trial Manager

Raleigh, NC · On-site

Clinical Trial Manager - Phase I oncology ICON is a global healthcare intelligence and clinical ... Manage the day-to-day operations of assigned trials and responsibilities to ensure completion per ...

ICON

Clinical Trial Manager

Raleigh, NC · On-site +1

Clinical Trial Manager - Phase I oncology ICON is a global healthcare intelligence and clinical ... Manage the day-to-day operations of assigned trials and responsibilities to ensure completion per ...

Care Access

Region Manager

Raleigh, NC · On-site

Oversee day-to-day operations at multiple clinical research sites within the region. * Ensure ... Manage site budgets and ensure adherence to financial agreements. * Support contract negotiations ...

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All JobsClinical Operation JobsClinical Operation Manager JobsClinical Operation Manager Jobs in Raleigh, NC

Clinical Operation Manager information

See Raleigh, NC salary details

$34K

$95.3K

$181.3K

How much do clinical operation manager jobs pay per year?

As of Aug 10, 2026, the average yearly pay for clinical operation manager in Raleigh, NC is $95,296.00, according to ZipRecruiter salary data. Most workers in this role earn between $70,500.00 and $110,300.00 per year, depending on experience, location, and employer.

What are some common challenges clinical operation managers face when coordinating multi-site clinical trials?

Clinical Operation Managers often encounter challenges such as ensuring consistent protocol adherence across all sites, managing communication among geographically dispersed teams, and maintaining timelines despite unexpected delays. They must also address regulatory differences between sites and troubleshoot issues related to patient recruitment and data collection. Success in this role requires strong organizational skills, adaptability, and effective collaboration with investigators, coordinators, and regulatory personnel.

What are the key skills and qualifications needed to thrive as a clinical operation manager?

To thrive as a Clinical Operation Manager, you need expertise in clinical project management, regulatory compliance, and a background in healthcare or life sciences, often supported by a relevant degree. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) tools, and certifications such as PMP or Six Sigma are commonly required. Strong leadership, problem-solving abilities, and excellent communication skills set top performers apart in this role. These competencies are essential for ensuring efficient clinical operations, maintaining regulatory standards, and leading teams to deliver successful trial outcomes.

What is a clinical operation manager?

Clinical Operation Managers are professionals responsible for overseeing the daily operations of clinical research sites, medical facilities, or departments. They ensure that clinical trials or healthcare services are conducted efficiently, comply with regulations, and meet quality standards. Their duties often include supervising staff, managing budgets, implementing policies, and coordinating between various teams. Clinical Operation Managers play a crucial role in ensuring that patient care and research activities run smoothly and effectively.

What is the difference between Clinical Operation Manager vs Clinical Research Coordinator?

AspectClinical Operation ManagerClinical Research Coordinator
CredentialsBachelor's degree in health sciences, life sciences, or related field; often with project management certificationsBachelor's degree in health sciences, nursing, or related field; often with research-specific training
Work EnvironmentOversees multiple clinical trials, manages teams, and ensures compliance at a departmental levelCoordinates daily activities of clinical trials, interacts directly with participants and investigators
Employer & IndustryPharmaceutical companies, biotech firms, hospitals, research institutionsResearch sites, hospitals, academic institutions, contract research organizations

The Clinical Operation Manager focuses on overseeing clinical trial operations, managing teams, and ensuring compliance across projects. In contrast, the Clinical Research Coordinator handles the day-to-day activities of specific trials, working closely with participants and investigators. Both roles require relevant healthcare or science credentials, but their scope and responsibilities differ significantly.

What are popular job titles related to Clinical Operation Manager jobs in Raleigh, NC? For Clinical Operation Manager jobs in Raleigh, NC, the most frequently searched job titles are:
What job categories do people searching Clinical Operation Manager jobs in Raleigh, NC look for? The top searched job categories for Clinical Operation Manager jobs in Raleigh, NC are:
What cities near Raleigh, NC are hiring for Clinical Operation Manager jobs? Cities near Raleigh, NC with the most Clinical Operation Manager job openings:
Clinical Operation Manager jobs near you
Infographic showing various Clinical Operation Manager job openings in Raleigh, NC as of August 2026, with employment types broken down into 100% Full Time. Highlights an 50% In-person, and 50% Remote job distribution, with an average salary of $95,296 per year, or $45.8 per hour.

Clinical Research Associate II - Psychiatry - United States (Remote)

Worldwide Clinical Trials

Durham, NC • On-site, Remote

Full-time

Re-posted 18 days ago

Job description

Who we are

We're a global, midsize CRO that pushes boundaries, innovates and invents because the path to a cure for the world's most persistent diseases is not paved by those who play it safe. It is built by those who take pioneering, creative approaches and implement them with quality and excellence.

We are Worldwide Clinical Trials, and we are a global team of over 3,500+ experts, bright thinkers, dreamers and doers and, together, we are changing the way the world experiences CROs - in the best possible way.

Our mission is to work with passion and purpose every day to improve lives and we are looking for others who value this same pursuit.

Why Worldwide

We believe everyone plays an important role in making a world of difference for patients and their caregivers. From our hands-on, accessible leaders, to our cohesive and supportive teams, we are committed to enabling professionals from all backgrounds and experiences to succeed. We prioritize cultivating a diverse and inclusive environment that continues to promote collaboration and creativity. We are proud to be a workplace where people thrive by being themselves and are inspired to do their best work every day.Join us!

What Clinical Operations does at Worldwide

At Worldwide Clinical Trials, we invite you to embark on a rewarding journey within Clinical Operations, where your contributions will leave a profound impact on the lives of patients.

Are you a motivated Clinical Research Associate with 2-3 years of monitoring experience who is looking for more than just your next job? Are you seeking a company that will invest in your development, provide meaningful career progression, and give you the opportunity to work alongside experienced clinical research professionals?

If so, we'd love to hear from you.

We are looking for a CRA II who is eager to expand their monitoring expertise, build strong site relationships, and grow into a senior clinical operations role. This position is ideal for someone who has established a solid foundation in site monitoring and is ready to accelerate their career within a supportive, collaborative, and quality-focused organization.

What you will do

As a CRA II, you will play a critical role in ensuring the successful execution of clinical trials by:

  • Performing on-site and remote monitoring visits in accordance with protocol, GCP, ICH guidelines, and company SOPs

  • Building strong relationships with investigative sites and serving as a trusted partner

  • Reviewing source documents and verifying data accuracy

  • Identifying risks, issues, and trends at sites and proactively driving resolution

  • Supporting site activation, enrollment, maintenance, and closeout activities

  • Ensuring patient safety, data integrity, and protocol compliance

  • Preparing detailed monitoring reports and follow-up letters

  • Collaborating cross-functionally with CTMs, project teams, and site personnel

What you will bring to the role

  • Excellent interpersonal, oral, and written communication skills in English

  • Superior organizational skills with attention to detail

  • Ability to work with little or no supervision

  • Proficiency in Microsoft Office, CTMS, and EDC Systems

Your experience

Required Qualifications

  • 2 - 3 years of experience as a regional, traveling Clinical Research Associate

  • 4-year universitydegree OR Nursing Degree

  • Knowledge of ICH-GCP guidelines and regulatory requirements

  • Experience conducting monitoring visits across multiple sites

  • Strong organizational, communication, and problem-solving skills

  • Ability to manage priorities in a fast-paced environment

  • Experience in Psychiatry is required

  • Willingness to travel regionally required

Preferred Qualifications

  • Experience in a CRO environment

  • Exposure to multiple therapeutic areas

  • Experience with decentralized or hybrid trial models

  • Desire to take on increasing responsibility and grow within Clinical Operations

At Worldwide Clinical Trials, we are committed to fostering an inclusive and equitable workplace by providing transparent compensation.
The salary range for this position is annually (For hourly paid positions, the stated salary range reflects hourly rates):


United States of America - $79,500.00 - $158,500.00


The salary range provided is intended to give candidates an understanding of potential earnings. Compensation will fall within the provided range, and it not a guarantee of exact salary. The final salary will be determined based on relevant experience, performance, education, and internal equity. In addition to base salary, we offer a competitive benefits package depending on location. We ensure pay equity and transparency and comply with all applicable labor laws. Salary information will be discussed during the interview process, and we encourage candidates to inquire about compensation at any stage.

We love knowing that someone is going to have a better life because of the work we do.

To view our other roles, check out our careers page at Discover a world of difference at Worldwide!For more information on Worldwide, visit www.Worldwide.com or connect with us on LinkedIn.

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