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Weekend Prn Rn Jobs in Greenville, SC (NOW HIRING)

RN, PRN

Greenville, SC · On-site

$35 - $40/hr

Registered Nurse (RN) Cherrydale Post Acute - Greenville, SC $35-$40/hour | PRN schedule Hiring: 12 ... Weekend Only: Friday, Saturday, Sunday schedule About Us At Cherrydale Post Acute, we believe in ...

RN, PRN

Greenville, SC · On-site

$35 - $40/hr

Registered Nurse (RN) Cherrydale Post Acute - Greenville, SC $35-$40/hour | PRN schedule Hiring: 12 ... Weekend Only: Friday, Saturday, Sunday schedule About Us At Cherrydale Post Acute, we believe in ...

RN, PRN

Greenville, SC · On-site

$35 - $40/hr

Registered Nurse (RN) Cherrydale Post Acute - Greenville, SC $35-$40/hour | PRN schedule Hiring: 12 ... Weekend Only: Friday, Saturday, Sunday schedule About Us At Cherrydale Post Acute, we believe in ...

RN, PRN

Simpsonville, SC · On-site

$33 - $35/hr

Registered Nurse (RN) - PRN $33-$35/hour Simpsonville, SC PRN / Flexible Scheduling About Us At Simpsonville Post Acute , we believe in showing appreciation in ways that truly matter. Through Acts of ...

Registered Nurse (RN) - PRN $33-$35/hour Simpsonville, SC PRN / Flexible Scheduling About Us At Simpsonville Post Acute , we believe in showing appreciation in ways that truly matter. Through Acts of ...

RN, PRN

Simpsonville, SC · On-site

$33 - $35/hr

Registered Nurse (RN) - PRN $33-$35/hour Simpsonville, SC PRN / Flexible Scheduling About Us At Simpsonville Post Acute , we believe in showing appreciation in ways that truly matter. Through Acts of ...

Showing results 21-40

Weekend Prn Rn information

See Greenville, SC salary details

$18

$34

$50

How much do weekend prn rn jobs pay per hour?

As of Aug 8, 2026, the average hourly pay for weekend prn rn in Greenville, SC is $34.30, according to ZipRecruiter salary data. Most workers in this role earn between $27.36 and $39.57 per hour, depending on experience, location, and employer.

What are the typical shift expectations and workload for a Weekend PRN RN?

Weekend PRN RN positions usually require nurses to work flexible hours on Saturdays and Sundays, with potential opportunities for additional shifts based on staffing needs. The workload can vary each weekend, depending on patient census and acuity, so adaptability is important. These roles often involve collaborating with a leaner weekend team, requiring strong teamwork and autonomy. While you may not have a set schedule every week, PRN positions can offer valuable hands-on experience and are ideal for nurses seeking flexibility or supplemental income.

What are the key skills and qualifications needed to thrive in the Weekend PRN RN position, and why are they important?

To thrive as a Weekend PRN RN, you need a current RN license, strong clinical assessment abilities, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems, medication administration protocols, and facility-specific safety procedures is important. Flexibility, excellent communication, and the ability to work independently are valuable soft skills for managing varied shifts and patient needs. These competencies ensure that you can provide high-quality care and respond effectively to weekend staffing and patient demands.

What is a Weekend PRN RN?

A Weekend PRN RN (As Needed Registered Nurse) is a nursing position where the nurse works primarily on weekends and on an as-needed basis. These roles are typically found in hospitals, nursing homes, and healthcare facilities that require additional weekend staffing. PRN nurses do not usually have a set schedule and may be called to fill in for staff shortages. This role offers flexibility but may not guarantee a certain number of hours. Weekend PRN RNs must still meet licensing and certification requirements like full-time nurses.

What are the most commonly searched types of Prn Rn jobs in Greenville, SC? The most popular types of Prn Rn jobs in Greenville, SC are:
What are popular job titles related to Weekend Prn Rn jobs in Greenville, SC? For Weekend Prn Rn jobs in Greenville, SC, the most frequently searched job titles are:
What job categories do people searching Weekend Prn Rn jobs in Greenville, SC look for? The top searched job categories for Weekend Prn Rn jobs in Greenville, SC are:
What cities near Greenville, SC are hiring for Weekend Prn Rn jobs? Cities near Greenville, SC with the most Weekend Prn Rn job openings:
Infographic showing various Weekend Prn Rn job openings in Greenville, SC as of August 2026, with employment types broken down into 21% As Needed, 36% Full Time, 41% Part Time, and 2% Contract. Highlights an 100% In-person job distribution, with an average salary of $71,335 per year, or $34.3 per hour.

PRN-Registered Nurse (RN) Tier 2 - Resource Pool

Spartanburg Regional Healthcare System

Greer, SC • On-site

Other

Posted 25 days ago


Spartanburg Regional Healthcare System rating

6.7

Company rating: 6.7 out of 10

Based on 117 frontline employees who took The Breakroom Quiz

533rd of 887 rated healthcare providers


Job description

Job Requirements

Experienced Registered Nurse - Pelham Medical Center (Resource Pool)

Join a team that values your growth, your well-being, and your future.


The Resource Pool at Pelham Medical Center, a part of Spartanburg Regional Healthcare System, is seeking RNs, with at least 2 years of experience, to join our dynamic team.


Why Pelham Medical Center?

Since 2008, Pelham Medical Center has been delivering award-winning care in a state-of-the-art facility designed for comfort and efficiency. As part of Spartanburg Regional Healthcare System, we're committed to excellence-for our patients and our team.


What We Offer:

  • Tuition Reimbursement for continued education
  • Self-Scheduling for better work-life balance
  • Wellness & Mental Health Resources to support you
  • Career Ladder & Leadership Development for experienced nurses

About the Unit:

  • Nurses within the Resource Pool at Pelham Medical Center, may provide care in all areas of the hospital, based on need. (Med Surg, ICU, ER, PACU)

Schedule

The PRN Tier 2 Nurse must work:

        Twelve (12) 12-hour shifts in a 6-week period.

        Three (3) of the 8 shifts must be a weekend.

        Will be placed on a Holiday Track


What You'll Do:

  • Deliver evidence-based, compassionate care
  • Collaborate with a highly engaged, multidisciplinary team
  • Participate in professional development and unit-based committees
  • Advocate for patients and ensure continuity of care

Minimum Requirements:

  • Graduate of an accredited nursing program
  • Current SC or compact state RN license
  • BLS certification

Preferred Requirements:

        2 years of RN experience


Ready to grow your nursing career?

  • Apply today and join a team that puts people first-patients and nurses alike.

Employment Type: OTHER

What Spartanburg Regional Healthcare System employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom


Spartanburg Regional Healthcare System logo

About Spartanburg Regional Healthcare System

Sourced by ZipRecruiter

Spartanburg Regional Healthcare System is a leader in the healthcare industry, located in Spartanburg, SC, US. As a comprehensive health system, it offers services encompassing everything from wellness, prevention, and care coordination to specific medical treatments for a wide range of diseases and health issues. Spartanburg Regional Healthcare System was founded in 1921 and has since developed a reputation for excellence and innovative care, growing to include six hospitals, 100 medical offices, 8,000 associates and more than 900 medical staff.

Industry

Recruiting and staffing services

Company size

5,001 - 10,000 Employees

Headquarters location

Spartanburg, SC, US

Year founded

1921