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Weekend Prn Rn Jobs in Greenville, SC (NOW HIRING)

PACS Inc

RN, PRN

Piedmont, SC · On-site

$34 - $36/hr

Registered Nurse (RN) - PRN Piedmont Post Acute - Piedmont, SC $34-$36/hour | PRN Opportunities ... Competitive pay: $34-$36/hour * $2/hour shift differential (nights & weekends) * Flexible PRN ...

PACS

RN, PRN

Piedmont, SC · On-site

$34 - $36/hr

Registered Nurse (RN) - PRN Piedmont Post Acute - Piedmont, SC $34-$36/hour | PRN Opportunities ... Competitive pay: $34-$36/hour * $2/hour shift differential (nights & weekends) * Flexible PRN ...

PACS

RN, PRN

Easley, SC · On-site

$36 - $40/hr

Registered Nurse (RN) - PRN Fleetwood Post Acute - Easley, SC $36-$40/hour | PRN | Flexible Scheduling About Us Fleetwood Post Acute is a 102-bed skilled nursing facility located in Easley, South ...

Premise Health

Registered Nurse - PRN

Greer, SC · On-site

As a PRN Registered Nurse, you'll provide care to client employees in our Health Center located in ... We are seeking a candidate with flexibility to work day, evening, night, and weekend shifts. What ...

Premise Health

Registered Nurse - PRN

Greer, SC · On-site

As a PRN Registered Nurse, you'll provide care to client employees in our Health Center located in ... We are seeking a candidate with flexibility to work day, evening, night, and weekend shifts. What ...

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All JobsPrn Rn JobsWeekend Prn Rn JobsWeekend Prn Rn Jobs in Greenville, SC

Weekend Prn Rn information

See Greenville, SC salary details

$18

$34

$50

How much do weekend prn rn jobs pay per hour?

As of Aug 20, 2026, the average hourly pay for weekend prn rn in Greenville, SC is $34.30, according to ZipRecruiter salary data. Most workers in this role earn between $27.36 and $39.57 per hour, depending on experience, location, and employer.

What is a Weekend PRN RN?

A Weekend PRN RN (As Needed Registered Nurse) is a nursing position where the nurse works primarily on weekends and on an as-needed basis. These roles are typically found in hospitals, nursing homes, and healthcare facilities that require additional weekend staffing. PRN nurses do not usually have a set schedule and may be called to fill in for staff shortages. This role offers flexibility but may not guarantee a certain number of hours. Weekend PRN RNs must still meet licensing and certification requirements like full-time nurses.

What are the typical shift expectations and workload for a Weekend PRN RN?

Weekend PRN RN positions usually require nurses to work flexible hours on Saturdays and Sundays, with potential opportunities for additional shifts based on staffing needs. The workload can vary each weekend, depending on patient census and acuity, so adaptability is important. These roles often involve collaborating with a leaner weekend team, requiring strong teamwork and autonomy. While you may not have a set schedule every week, PRN positions can offer valuable hands-on experience and are ideal for nurses seeking flexibility or supplemental income.

What are the key skills and qualifications needed to thrive in the Weekend PRN RN position, and why are they important?

To thrive as a Weekend PRN RN, you need a current RN license, strong clinical assessment abilities, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems, medication administration protocols, and facility-specific safety procedures is important. Flexibility, excellent communication, and the ability to work independently are valuable soft skills for managing varied shifts and patient needs. These competencies ensure that you can provide high-quality care and respond effectively to weekend staffing and patient demands.

Do PRN registered nurses have to work weekends?

PRN registered nurses are scheduled on an as-needed basis and are not typically required to work weekends unless assigned to weekend shifts. Their work schedule depends on the facility's staffing needs and the nurse's availability, often offering flexibility. However, some PRN positions may include weekend shifts if the facility requires coverage during those times.

What are the most commonly searched types of Prn Rn jobs in Greenville, SC?

The most popular types of Prn Rn jobs in Greenville, SC are:

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For Weekend Prn Rn jobs in Greenville, SC, the most frequently searched job titles are:

What job categories do people searching Weekend Prn Rn jobs in Greenville, SC look for?

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What cities near Greenville, SC are hiring for Weekend Prn Rn jobs?

Cities near Greenville, SC with the most Weekend Prn Rn job openings:

Weekend Prn Rn jobs near you
Infographic showing various Weekend Prn Rn job openings in Greenville, SC as of August 2026, with employment types broken down into 1% As Needed, 69% Full Time, 25% Part Time, 4% Contract, and 1% Nights. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $71,335 per year, or $34.3 per hour.

PRN Registered Nurse

Summit Spine & Joint Centers

Greenville, SC • On-site

Other

Posted 2 days ago

New

Job description

PRN Registered Nurse Opportunity At Summit Spine And Joint Centers

Summit Spine and Joint Centers (SSJC) is a rapidly growing, multi-state spine and joint care organization providing integrated clinical, surgical, and imaging services. With clinic locations across Georgia, North Carolina, South Carolina, and Tennessee, our care teams include IPS in North Carolina and Savannah Pain Management in Georgia, all operating as part of the SSJC organization. We are committed to collaboration, high-quality patient-centered care, and supporting our teams as we continue to expand. We are seeking motivated, qualified professionals to join us in delivering exceptional care across our growing network. We are seeking a PRN, self-motivated Registered Nurse for our Greensville clinic who loves to transform lives through exceptional patient care!

Responsibilities:

  • Effectively manages the care of assigned patients using knowledge, skills, judgment, and decision-making skills for the specific area and patient population.
  • Delivers patient care utilizing standardized evidenced based guidelines of care and appropriate resources, including personnel, services, supplies and equipment.
  • Monitor and report changes in patient symptoms or behavior, administer medications and document all encounters and progress notes.
  • Communicate with collaborating physicians or specialists regarding patient care
  • Educates patients about health maintenance and disease prevention
  • Educates care plans, provides emotional support and advise to patients and their family members
  • The employee must communicate professionally, respectfully, and effectively with patients, visitors, clinicians, coworkers, and vendors, including in busy, demanding, or stressful circumstances.
  • The employee must maintain professional composure and consistently perform assigned duties throughout the scheduled work period; manage routine workplace stressors and feedback without disrupting patient care, patient-facing operations, or coworkers' work; and use established de-escalation and escalation procedures when appropriate.
  • The employee must exercise sound judgment; maintain appropriate workplace boundaries; receive and respond to routine feedback and direction; protect confidential patient and business information; and address patient or workplace concerns through established supervisory and safety procedures. These functions are essential to the position.

Qualifications:

  • Good standing RN License for the state of South Carolina without limitations
  • BLS and ALS/ACLS Certified
  • Familiarity with medical software and equipment
  • Ability to build rapport with patients
  • Strong problem solving and critical thinking skills
  • Ability to thrive in a fast-paced environment

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