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Weekend Prn Rn Jobs in Columbia, SC (NOW HIRING)

NATIONAL HEALTH- WHITE OAK GROUP

RN

Columbia, SC · On-site

PRN Registered Nurses (RN) Wanted! White Oak Manor of Columbia | Compassion. Dedication. Excellence. Are you a compassionate and skilled Registered Nurse looking to make a real impact in the lives of ...

Summit BHC

PRN RN-13

Peak, SC

PRN RN-13 | Peak Behavioral Health | Santa Teresa, New Mexico About the Job: PURPOSE STATEMENT: The Registered Nurse is responsible for providing nursing care to patients. Supervising care treatment ...

Encompass Health

Registered Nurse

Irmo, SC

Now offering a $10,000 Sign On Bonus for Full Time RNs! * Now hiring Full Time, Part Time and PRN RNs for Day and Night Shift * Weekend +1 option also available Encompass Health: Where Nursing Meets ...

Encompass Health

Registered Nurse

Columbia, SC

Now Hiring Full Time, Part Time and PRN RNs for Day Shift and Night Shift * CRRN Position Available Encompass Health: Where Nursing Meets Heart, Home, and Healing Are you seeking a nursing career ...

HealthSouth

Registered Nurse

Columbia, SC · On-site

Registered Nurse Career Opportunity * $10,000 Sign on Bonus for Full Time RNs! * Now Hiring Full Time, Part Time and PRN RNs for Day Shift and Night Shift Encompass Health: Where Nursing Meets Heart ...

PRN Healthcare

Travel IMC RN

Columbia, SC · On-site

PRN Healthcare is seeking a travel nurse RN Intermediate Care for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Intermediate Care * Discipline: RN * Start Date: 08/17 ...

PRN Healthcare

Travel Endoscopy RN

Columbia, SC · On-site

PRN Healthcare is seeking a travel nurse RN Endoscopy for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: Endoscopy * Discipline: RN * Start Date: 09/14/2026 * Duration ...

PRN Healthcare

Travel OR RN

Camden, SC · On-site

PRN Healthcare is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Camden, South Carolina. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Start Date: 08 ...

PRN Healthcare

Travel ER RN

Columbia, SC · On-site

PRN Healthcare is seeking a travel nurse RN ED - Emergency Department for a travel nursing job in Columbia, South Carolina. & Requirements * Specialty: ED - Emergency Department * Discipline: RN * ...

PRN Healthcare

Travel OR RN

Camden, SC · On-site

PRN Healthcare is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Camden, South Carolina. & Requirements * Specialty: OR - Operating Room * Discipline: RN * Start Date: 08 ...

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All JobsPrn Rn JobsWeekend Prn Rn JobsWeekend Prn Rn Jobs in Columbia, SC

Weekend Prn Rn information

See Columbia, SC salary details

$18

$33

$49

How much do weekend prn rn jobs pay per hour?

As of Aug 3, 2026, the average hourly pay for weekend prn rn in Columbia, SC is $33.74, according to ZipRecruiter salary data. Most workers in this role earn between $26.92 and $38.89 per hour, depending on experience, location, and employer.

How to make $300,000 as a nurse?

To earn $300,000 as a Weekend PRN RN, nurses can increase their income by working multiple shifts, obtaining specialized certifications, and gaining experience in high-demand areas like critical care or anesthesia. Some may also supplement income through travel nursing or per diem assignments that pay higher rates for weekend shifts.

What are the typical shift expectations and workload for a Weekend PRN RN position?

Weekend PRN RN positions usually require nurses to work flexible hours on Saturdays and Sundays, with potential opportunities for additional shifts based on staffing needs. The workload can vary each weekend, depending on patient census and acuity, so adaptability is important. These roles often involve collaborating with a leaner weekend team, requiring strong teamwork and autonomy. While you may not have a set schedule every week, PRN positions can offer valuable hands-on experience and are ideal for nurses seeking flexibility or supplemental income.

What are the key skills and qualifications needed to thrive in the Weekend Prn Rn position, and why are they important?

To thrive as a Weekend PRN RN, you need a current RN license, strong clinical assessment abilities, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems, medication administration protocols, and facility-specific safety procedures is important. Flexibility, excellent communication, and the ability to work independently are valuable soft skills for managing varied shifts and patient needs. These competencies ensure that you can provide high-quality care and respond effectively to weekend staffing and patient demands.

Do PRN nurses have to work weekends?

PRN (as-needed) RNs working weekends depends on the facility's staffing needs and scheduling policies. Some PRN nurses choose to work weekends, while others may have the option to decline, as PRN positions typically offer flexible hours. It is important to clarify scheduling expectations with the employer before accepting the role.

How to make 150,000 as a nurse?

To earn $150,000 as a Weekend PRN RN, nurses can increase their hourly rate through specialized skills, certifications, or working in high-demand areas such as intensive care or emergency rooms. Working additional shifts, overtime, or in multiple facilities can also boost income, especially when scheduling is flexible on weekends. Building experience and negotiating pay rates are key factors in reaching higher salary goals.

What is a Weekend PRN RN job?

A Weekend PRN RN (As Needed Registered Nurse) is a nursing position where the nurse works primarily on weekends and on an as-needed basis. These roles are typically found in hospitals, nursing homes, and healthcare facilities that require additional weekend staffing. PRN nurses do not usually have a set schedule and may be called to fill in for staff shortages. This role offers flexibility but may not guarantee a certain number of hours. Weekend PRN RNs must still meet licensing and certification requirements like full-time nurses.

How to make an extra $2000 a month as a nurse?

A Weekend PRN RN can increase income by taking on additional shifts, working overtime, or picking up per diem assignments during busy periods. Gaining specialized certifications or skills, such as in critical care or anesthesia, can also command higher pay rates. Scheduling flexibility and experience can help maximize earning potential to reach an extra $2000 monthly.
What are the most commonly searched types of Prn Rn jobs in Columbia, SC? The most popular types of Prn Rn jobs in Columbia, SC are:
What are popular job titles related to Weekend Prn Rn jobs in Columbia, SC? For Weekend Prn Rn jobs in Columbia, SC, the most frequently searched job titles are:
What job categories do people searching Weekend Prn Rn jobs in Columbia, SC look for? The top searched job categories for Weekend Prn Rn jobs in Columbia, SC are:
What cities near Columbia, SC are hiring for Weekend Prn Rn jobs? Cities near Columbia, SC with the most Weekend Prn Rn job openings:
Weekend Prn Rn jobs near you
Infographic showing various Weekend Prn Rn job openings in Columbia, SC as of July 2026, with employment types broken down into 2% Locum Tenens, 13% As Needed, 43% Full Time, 29% Part Time, and 13% Contract. Highlights an 100% In-person job distribution, with an average salary of $70,185 per year, or $33.7 per hour.

Registered Nurse PRN (MCP)- Elgin Urgent Care

MUSC

Elgin, SC • On-site

Per diem

Re-posted 3 days ago

MUSC Health rating

7.0

Company rating: 7.0 out of 10

Based on 198 frontline employees who took The Breakroom Quiz

412th of 887 rated healthcare providers

Job description

Job Description Summary

Join MUSC Community Physicians as a PRN Registered Nurse and enjoy the flexibility to balance your career with your lifestyle while making a meaningful impact on patients throughout the Midlands.
At MUSC Health Elgin Urgent Care, you’ll be part of a collaborative team committed to delivering high-quality, compassionate care in a fast-paced outpatient setting. Whether you’re looking to supplement your current position or maintain flexibility in your nursing career, this is an excellent opportunity to put your skills to work with South Carolina’s leading academic health system.
Why You’ll Love This Opportunity

What MUSC Health employees say

Pay

Benefits

Hours and flexibility

Workplace

Get the full story on Breakroom

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About MUSC Health

Sourced by ZipRecruiter

MUSC is located in Charleston, SC, frequently named one of the best places in America to live. If charming, historic, vibrant, cultural, and coastal are adjectives that you find appealing, it's all here. In Charleston, you might find yourself dining at a world class restaurant tonight and relaxing on a boat as you explore our many waterways tomorrow. You might stroll along cobblestone streets, amidst centuries old homes by day and attend a jazz concert by night. Charleston is a place where you can live your life to its fullest.

Industry

Hospitality services

Company size

10,000+ Employees

Headquarters location

Charleston, SC, US

Year founded

1824

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