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Weekend Prn Rn Jobs in Charleston, SC (NOW HIRING)

PruittHealth

PRN Registered Nurse RN Hospice

Ladson, SC · On-site

$55.10 - $68.88/hr

- PRN Registered Nurse RN Hospice (2609407)PRN Registered Nurse RN Hospice - 2609407DescriptionREGISTERED NURSE (RN) CASE MANAGER - HOSPICE SERVICES - PRN Available Join the PruittHealth Hospice family ...

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All JobsPrn Rn JobsWeekend Prn Rn JobsWeekend Prn Rn Jobs in Charleston, SC

Weekend Prn Rn information

See Charleston, SC salary details

$18

$34

$51

How much do weekend prn rn jobs pay per hour?

As of Sep 7, 2026, the average hourly pay for weekend prn rn in Charleston, SC is $34.64, according to ZipRecruiter salary data. Most workers in this role earn between $27.64 and $39.95 per hour, depending on experience, location, and employer.

What is a Weekend PRN RN?

A Weekend PRN RN (As Needed Registered Nurse) is a nursing position where the nurse works primarily on weekends and on an as-needed basis. These roles are typically found in hospitals, nursing homes, and healthcare facilities that require additional weekend staffing. PRN nurses do not usually have a set schedule and may be called to fill in for staff shortages. This role offers flexibility but may not guarantee a certain number of hours. Weekend PRN RNs must still meet licensing and certification requirements like full-time nurses.

What are the typical shift expectations and workload for a Weekend PRN RN?

Weekend PRN RN positions usually require nurses to work flexible hours on Saturdays and Sundays, with potential opportunities for additional shifts based on staffing needs. The workload can vary each weekend, depending on patient census and acuity, so adaptability is important. These roles often involve collaborating with a leaner weekend team, requiring strong teamwork and autonomy. While you may not have a set schedule every week, PRN positions can offer valuable hands-on experience and are ideal for nurses seeking flexibility or supplemental income.

What are the key skills and qualifications needed to thrive in the Weekend PRN RN position, and why are they important?

To thrive as a Weekend PRN RN, you need a current RN license, strong clinical assessment abilities, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems, medication administration protocols, and facility-specific safety procedures is important. Flexibility, excellent communication, and the ability to work independently are valuable soft skills for managing varied shifts and patient needs. These competencies ensure that you can provide high-quality care and respond effectively to weekend staffing and patient demands.

Do PRN registered nurses have to work weekends?

PRN registered nurses are scheduled on an as-needed basis and are not typically required to work weekends unless assigned to weekend shifts. Their work schedule depends on the facility's staffing needs and the nurse's availability, often offering flexibility. However, some PRN positions may include weekend shifts if the facility requires coverage during those times.

What are the most commonly searched types of Prn Rn jobs in Charleston, SC?

The most popular types of Prn Rn jobs in Charleston, SC are:

What are popular job titles related to Weekend Prn Rn jobs in Charleston, SC?

For Weekend Prn Rn jobs in Charleston, SC, the most frequently searched job titles are:

What job categories do people searching Weekend Prn Rn jobs in Charleston, SC look for?

The top searched job categories for Weekend Prn Rn jobs in Charleston, SC are:

What cities near Charleston, SC are hiring for Weekend Prn Rn jobs?

Cities near Charleston, SC with the most Weekend Prn Rn job openings:

Weekend Prn Rn jobs near you
Infographic showing various Weekend Prn Rn job openings in Charleston, SC as of August 2026, with employment types broken down into 2% Locum Tenens, 21% As Needed, 40% Full Time, 21% Part Time, 14% Contract, and 2% Nights. Highlights an 100% In-person job distribution, with an average salary of $72,052 per year, or $34.6 per hour.

PRN Registered Nurse

H/K/B Cosmetic Surgery

Mount Pleasant, SC • On-site

Other

Posted 3 days ago

New

Job description

PRN Registered Nurse

We have an exciting opportunity for a PRN Registered Nurse to join our upscale plastic surgery center!

A bit about the position: Promotes and restores patients' health for H/K/B patients by completing the nursing process; collaborating with physicians and multidisciplinary team members; providing physical and psychological support to patients, friends, and families. Shifts are 8-12 hours between the hours of 6:00 am - 6:00 pm, as needed.

What you can expect in the role:

  • Protects patients and employees by adhering to infection-control policies and protocols, medication administration and storage procedures, and controlled substance regulations.
  • Helps preop patients prior to surgery, circulate during surgeries and recover patients post-surgery.
  • Maintains safe and clean working environment by complying with procedures, rules, and regulations; calling for assistance from health care support personnel.

What we are looking for in a candidate:

  • 1 year of PACU experience and 1 year of OR circulating experience required.
  • Associates degree required. Bachelor's degree preferred.
  • Equivalent combination of education and experience.
  • Current RN license, BLS, and ACLS certifications required.
  • Industry experience a plus.

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