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Weekend Prn Rn Jobs in Charleston, SC (NOW HIRING)

MUSC

PRN Registered Nurse - Urology

Charleston, SC · On-site

Additional RN I Required Minimum Training and Education: Associate's Degree required. Required Licensure, Certifications, Registrations: Licensure as a Registered Nurse by the South Carolina Board of ...

Interim Healthcar

Hospice RN - PRN

North Charleston, SC · On-site

$52.35 - $71.64/hr

PRN Hospice RN Seeking a nursing opportunity where you can make a real impact? Interim HealthCare ... Provide home-based care to hospice patients after-hours, weekdays, weekends, and as needs arise

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Weekend Prn Rn information

See Charleston, SC salary details

$18

$34

$51

How much do weekend prn rn jobs pay per hour?

As of Sep 5, 2026, the average hourly pay for weekend prn rn in Charleston, SC is $34.64, according to ZipRecruiter salary data. Most workers in this role earn between $27.64 and $39.95 per hour, depending on experience, location, and employer.

What is a Weekend PRN RN?

A Weekend PRN RN (As Needed Registered Nurse) is a nursing position where the nurse works primarily on weekends and on an as-needed basis. These roles are typically found in hospitals, nursing homes, and healthcare facilities that require additional weekend staffing. PRN nurses do not usually have a set schedule and may be called to fill in for staff shortages. This role offers flexibility but may not guarantee a certain number of hours. Weekend PRN RNs must still meet licensing and certification requirements like full-time nurses.

What are the typical shift expectations and workload for a Weekend PRN RN?

Weekend PRN RN positions usually require nurses to work flexible hours on Saturdays and Sundays, with potential opportunities for additional shifts based on staffing needs. The workload can vary each weekend, depending on patient census and acuity, so adaptability is important. These roles often involve collaborating with a leaner weekend team, requiring strong teamwork and autonomy. While you may not have a set schedule every week, PRN positions can offer valuable hands-on experience and are ideal for nurses seeking flexibility or supplemental income.

What are the key skills and qualifications needed to thrive in the Weekend PRN RN position, and why are they important?

To thrive as a Weekend PRN RN, you need a current RN license, strong clinical assessment abilities, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems, medication administration protocols, and facility-specific safety procedures is important. Flexibility, excellent communication, and the ability to work independently are valuable soft skills for managing varied shifts and patient needs. These competencies ensure that you can provide high-quality care and respond effectively to weekend staffing and patient demands.

Do PRN registered nurses have to work weekends?

PRN registered nurses are scheduled on an as-needed basis and are not typically required to work weekends unless assigned to weekend shifts. Their work schedule depends on the facility's staffing needs and the nurse's availability, often offering flexibility. However, some PRN positions may include weekend shifts if the facility requires coverage during those times.

What are the most commonly searched types of Prn Rn jobs in Charleston, SC?

The most popular types of Prn Rn jobs in Charleston, SC are:

What are popular job titles related to Weekend Prn Rn jobs in Charleston, SC?

For Weekend Prn Rn jobs in Charleston, SC, the most frequently searched job titles are:

What job categories do people searching Weekend Prn Rn jobs in Charleston, SC look for?

The top searched job categories for Weekend Prn Rn jobs in Charleston, SC are:

What cities near Charleston, SC are hiring for Weekend Prn Rn jobs?

Cities near Charleston, SC with the most Weekend Prn Rn job openings:

Weekend Prn Rn jobs near you
Infographic showing various Weekend Prn Rn job openings in Charleston, SC as of August 2026, with employment types broken down into 2% Locum Tenens, 21% As Needed, 40% Full Time, 21% Part Time, 14% Contract, and 2% Nights. Highlights an 100% In-person job distribution, with an average salary of $72,052 per year, or $34.6 per hour.

PRN Registered Nurse - Allergy - MUSCP

MUSC Health & Medical University of SC

Charleston, SC • On-site

Part-time

This job post has expired 2 days ago. Applications are no longer accepted.

MUSC Health rating

7.0

Company rating: 7.0 out of 10

Based on 202 frontline employees who took The Breakroom Quiz

421st of 898 rated healthcare providers

Job description

Job Description Summary
Responsible for providing quality nursing care while maintaining accountability for the coordination of patient care.
Entity
University Medical Associates (UMA) Only Employees and Financials
Worker Type
Employee
Worker Sub-Type
PRN
Cost Center
CC001992 UMA AMB MULT West Campus Multi Specialty CC
Pay Rate Type
Hourly
Pay Grade
Health-28
Scheduled Weekly Hours
8
Work Shift
Job Description
  • Provides nursing care to patients using the nursing process (assessment, planning, implementation, and evaluation).
  • Directs and leads other assigned team members and collaborates with multidisciplinary team members to provide age/developmentally appropriate care in accordance with nursing standards of care and practice.
  • Provide patient/family centered care using the nursing process and focusing on the physical, emotional, spiritual, cultural, religious, and environmental needs. This includes providing for the assessment, development of nursing diagnoses, outcome identification, planning, implementation of interventions, coordination of care, health teaching and promotion and evaluation of goals and interventions consistent with the policies of MUSC.
  • Maintains a safe, therapeutic, and healing environment through ensuring patient privacy and responsive, respectful, accepting, and professional behavior. Demonstrates the ability to function in a professional setting through active participation in a professional practice model. This includes participating in shared governance, adherence to standards of care, participation in peer review and professional development promoting leadership and clinical excellence, effective team skills, autonomous practice and acknowledgment of accountability for actions and critical thinking.
  • Coordinates the effective and efficient delivery of patient care services through the application of care management principles. Identifies clinical priorities and initiates action to improve patient outcomes.
  • Demonstrates ability to function in a professional practice model through active participation in shared governance, promotion of a healthy work environment and acceptance of personal responsibility for professional growth.

Additional Job Description
RN I
Required Minimum Training and Education: Associate's Degree required.
Required Licensure, Certifications, Registrations: Licensure as a Registered Nurse by the South Carolina Board of Nursing or a compact state. Current American Heart Association (AHA) Basic Life Support (BLS) certification or American Red Cross BLS for Healthcare Providers certification is required.
Physical Requirements: Continuous requirements are to perform job functions while standing, walking and sitting. Ability to bend at the waist, kneel, climb stairs, reach in all directions, fully use both hands and legs, possess good finger dexterity, perform repetitive motions with hands/wrists/elbows and shoulders, reach in all directions. Ability to be qualified physically for respirator use, initially and as required. Maintain 20/40 vision corrected, see and recognize objects close at hand and at a distance, work in a latex safe environment and work indoors. Frequently lift, lower, push and pull and/or carry objects weighing 50 lbs (+/-) unassisted, exert up to 50 lbs of force, lift from 36" to overhead 25 lbs. Infrequently work in dusty areas and confined/cramped spaces.
RN II
Required Minimum Training and Education: Associate's Degree, and a minimum of one (1) year of work experience as a Registered Nurse required.
Required Licensure, Certifications, Registrations: Licensure as a Registered Nurse by the South Carolina Board of Nursing or a compact state. Current American Heart Association (AHA) Basic Life Support (BLS) certification or American Red Cross BLS for Healthcare Providers certification is required.
Physical Requirements: Continuous requirements are to perform job functions while standing, walking and sitting. Ability to bend at the waist, kneel, climb stairs, reach in all directions, fully use both hands and legs, possess good finger dexterity, perform repetitive motions with hands/wrists/elbows and shoulders, reach in all directions. Ability to be qualified physically for respirator use, initially and as required. Maintain 20/40 vision corrected, see and recognize objects close at hand and at a distance, work in a latex safe environment and work indoors. Frequently lift, lower, push and pull and/or carry objects weighing 50 lbs (+/-) unassisted, exert up to 50 lbs of force, lift from 36" to overhead 25 lbs. Infrequently work in dusty areas and confined/cramped spaces.
If you like working with energetic enthusiastic individuals, you will enjoy your career with us!
The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.
Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees

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About MUSC Health

Sourced by ZipRecruiter

MUSC is located in Charleston, SC, frequently named one of the best places in America to live. If charming, historic, vibrant, cultural, and coastal are adjectives that you find appealing, it's all here. In Charleston, you might find yourself dining at a world class restaurant tonight and relaxing on a boat as you explore our many waterways tomorrow. You might stroll along cobblestone streets, amidst centuries old homes by day and attend a jazz concert by night. Charleston is a place where you can live your life to its fullest.

Industry

Hospitality services

Company size

10,000+ Employees

Headquarters location

Charleston, SC, US

Year founded

1824

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