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Weekend Prn Rn Jobs in Charleston, SC (NOW HIRING)

Do you have the career opportunities as a PRN RN Infusion you want with your current employer? We have an exciting opportunity for you to join HCA Healthcare Trident Hospital which is part of the ...

Registered Nurse (RN) - PRN Position Summary The Registered Nurse (RN) will provide primary care coordination for patients and implement a collaborative care plan as prescribed by the physician and ...

Registered Nurse (RN) - PRN Position Summary The Registered Nurse (RN) will provide primary care coordination for patients and implement a collaborative care plan as prescribed by the physician and ...

REGISTERED NURSE (RN) CASE MANAGER - HOSPICE SERVICES - PRN Available Join the PruittHealth Hospice family, where the health and safety of our workforce is our top priority! We're not only committed ...

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Weekend Prn Rn information

See Charleston, SC salary details

$18

$34

$51

How much do weekend prn rn jobs pay per hour?

As of Aug 18, 2026, the average hourly pay for weekend prn rn in Charleston, SC is $34.79, according to ZipRecruiter salary data. Most workers in this role earn between $27.74 and $40.14 per hour, depending on experience, location, and employer.

What is a Weekend PRN RN?

A Weekend PRN RN (As Needed Registered Nurse) is a nursing position where the nurse works primarily on weekends and on an as-needed basis. These roles are typically found in hospitals, nursing homes, and healthcare facilities that require additional weekend staffing. PRN nurses do not usually have a set schedule and may be called to fill in for staff shortages. This role offers flexibility but may not guarantee a certain number of hours. Weekend PRN RNs must still meet licensing and certification requirements like full-time nurses.

What are the typical shift expectations and workload for a Weekend PRN RN?

Weekend PRN RN positions usually require nurses to work flexible hours on Saturdays and Sundays, with potential opportunities for additional shifts based on staffing needs. The workload can vary each weekend, depending on patient census and acuity, so adaptability is important. These roles often involve collaborating with a leaner weekend team, requiring strong teamwork and autonomy. While you may not have a set schedule every week, PRN positions can offer valuable hands-on experience and are ideal for nurses seeking flexibility or supplemental income.

What are the key skills and qualifications needed to thrive in the Weekend PRN RN position, and why are they important?

To thrive as a Weekend PRN RN, you need a current RN license, strong clinical assessment abilities, and experience in acute or long-term care settings. Familiarity with electronic health record (EHR) systems, medication administration protocols, and facility-specific safety procedures is important. Flexibility, excellent communication, and the ability to work independently are valuable soft skills for managing varied shifts and patient needs. These competencies ensure that you can provide high-quality care and respond effectively to weekend staffing and patient demands.

Do PRN registered nurses have to work weekends?

PRN registered nurses are scheduled on an as-needed basis and are not typically required to work weekends unless assigned to weekend shifts. Their work schedule depends on the facility's staffing needs and the nurse's availability, often offering flexibility. However, some PRN positions may include weekend shifts if the facility requires coverage during those times.

What are the most commonly searched types of Prn Rn jobs in Charleston, SC?

The most popular types of Prn Rn jobs in Charleston, SC are:

What are popular job titles related to Weekend Prn Rn jobs in Charleston, SC?

For Weekend Prn Rn jobs in Charleston, SC, the most frequently searched job titles are:

What cities near Charleston, SC are hiring for Weekend Prn Rn jobs?

Cities near Charleston, SC with the most Weekend Prn Rn job openings:

Infographic showing various Weekend Prn Rn job openings in Charleston, SC as of August 2026, with employment types broken down into 2% Locum Tenens, 23% As Needed, 25% Full Time, 35% Part Time, and 15% Contract. Highlights an 96% In-person, and 4% Remote job distribution, with an average salary of $72,357 per year, or $34.8 per hour.

PRN Endoscopy Registered Nurse

Lowcountry Endoscopy Center LLC

Lincolnville, SC • On-site

Other

Posted 14 days ago


Job description

Charleston GI has been developing since 1989, our practice is the first and largest gastroenterology practice in the Lowcountry to operate a physicians' practice and three nationally certified and state licensed endoscopy centers. Our team includes ten outstanding Board Certified Gastroenterologists, with a combined experience of over 100 years of treating patients. We value the health, service, and satisfaction of our patients above all else.
JOB SUMMARY
The Registered Nurse provides nursing care to patients on the Endoscopy Unit in terms of individual needs, according to physicianâ€'s orders and in conformity with recognized nursing practice and established policies and procedures. Tasks include, but are not limited to the pre-procedure and post-procedure care of patients scheduled for endoscopic and InterStim procedures. The Registered Nurse initiates and assists with emergency measures as needed. The Registered Nurse may supervise other licensed and unlicensed personnel as instructed by the Director of Nursing, Assistant Director of Nursing, or Charge Nurse. The center is an outpatient facility equipped for diagnostic and therapeutic GI endoscopy procedures. The patient population includes adolescent through geriatric with over 90% of patients age 30 or older. Medical care is managed by physicians who have been privileged and credentialed by the Board of Directors.
QUALIFICATIONS

  • Experience: At least one year clinical experience in a healthcare setting
  • Knowledge/Skills:
  • Knowledge of the professional nursing theory and practice, to give and evaluate patient care
  • Knowledge of organizational policies and procedures to administer patient care
  • Knowledge of common safety hazards and precautions to establish a safe work environment
  • Demonstrates initiative, insight and judgment in making decisions.
  • Skill in applying and modifying the principles, methods and techniques of professional nursing to provide on-going patient care
  • Skill in identifying problems and recommending solutions
  • Skill in complete and thorough documentation
  • Skill in establishing and maintaining effective working relationships with patients, medical staff and the public
  • Ability to analyze situations and apply critical thinking
  • Ability to communicate clearly
  • Ability to react calmly and effectively in emergency situations.
Requirements
REQUIRED
  • Education: Graduation from an accredited school or college of nursing.
PREFERRED
  • Experience: Clinical experience in Endoscopy, ER, OR, or ICU.
  • Knowledge/Skills:
  • Knowledge of endoscopy equipment and procedures
  • Basic computer and keyboard skills
  • Strong organization and communication skills
REQUIRED LICENSES/CERTIFICATIONS
  • Current licensure as a Registered Nurse in the state of South Carolina or current licensure as a Registered Nurse in another Compact state
  • Current BLS certification
  • PRN Registered Nurses are not required to maintain ACLS certification.

Summerville Endoscopy Center LLC is an EEO Employer - M/F/Disability/Protected Veteran Status