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Variant Curation Scientist Jobs (NOW HIRING)

Duke University

Biostatistician II

Durham, NC · On-site

... of fundamental scientific discoveries to improve human health locally and around the globe ... Genomic alignment and variant curation. * Maintain and curate project databases in collaboration ...

Duke University

Biostatistician II

Durham, NC

... of fundamental scientific discoveries to improve human health locally and around the globe ... Genomic alignment and variant curation. * Maintain and curate project databases in collaboration ...

Cincinnati Children's

Bioinformatics Analyst

Burnet, TX · On-site

$61.40K - $78.29K/yr

Executes pipelines for curating, processing and analyzing biomedical data of various types (e.g ... Works in collaboration with both technology and scientific teams. Requirements Gathering

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How much do variant curation scientist jobs pay per hour?

As of May 31, 2026, the average hourly pay for variant curation scientist in the United States is $38.99, according to ZipRecruiter salary data. Most workers in this role earn between $33.89 and $42.55 per hour, depending on experience, location, and employer.

What does a Variant Curation Scientist do?

A Variant Curation Scientist analyzes genetic variations to determine their clinical significance, aiding in patient diagnosis and treatment. They review scientific literature, apply bioinformatics tools, and follow established guidelines to classify genetic variants. Their work supports genetic testing laboratories, researchers, and healthcare providers by ensuring accurate interpretation of genetic data. Strong attention to detail, critical thinking, and knowledge of molecular genetics are essential for this role.

What are the key skills and qualifications needed to thrive in the Variant Curation Scientist position, and why are they important?

To thrive as a Variant Curation Scientist, you need a strong background in genetics, molecular biology, and bioinformatics, typically supported by an advanced degree in a relevant field. Experience with tools such as genome browsers, variant annotation software, and familiarity with databases like ClinVar are highly valued, and certification from organizations like the American Board of Medical Genetics and Genomics (ABMGG) is often preferred. Attention to detail, critical thinking, and strong written communication skills set top candidates apart in this role. These abilities are essential for accurately interpreting genetic data, collaborating with clinical teams, and contributing to high-quality patient care and research.

What does a typical workday look like for a Variant Curation Scientist?

A typical workday for a Variant Curation Scientist involves reviewing and interpreting genetic variants found in DNA sequencing data, updating and maintaining variant databases, and preparing detailed reports for clinical or research use. You may spend time collaborating closely with clinical geneticists, laboratory staff, and bioinformaticians to resolve challenging cases or discuss novel findings. Daily responsibilities also include literature review to stay current with emerging data and occasionally participating in team meetings or case conferences. The role is generally structured within a laboratory or research team, promoting a highly collaborative and knowledge-sharing environment.
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General Interest in Genomenon: Share your resume and we'll keep it on file!

General Interest in Genomenon: Share your resume and we'll keep it on file!

Genomenon

Chicago, IL

Full-time

Posted 12 days ago

Job description

Our Company

Genomenon is an AI-driven genetic intelligence company on a mission to save and improve lives by making biomedical information actionable. Rare diseases and cancer affect more than 30 million people in the U.S. alone and hundreds of millions globally, yet most patients still face long diagnostic journeys and limited treatment options. Our goal is clear and ambitious: to deliver the information that shapes diagnosis and treatment for every rare disease and cancer patient.

We sit at the intersection of AI, genomics, and real world evidence. Genomenon transforms the global scientific literature into a literature derived, real world evidence (RWE) engine for precision medicine—combining large-scale AI with expert human curation to deliver clean, clinically actionable datasets. This approach fills critical gaps left by EHR and claims data, especially in rare disease and oncology, by showing how patients actually present, progress, and respond to therapy.

We turn vast, complex biomedical data—spanning genomics, clinical evidence, and scientific literature—into trusted intelligence that helps clinicians make better diagnostic and therapeutic decisions, and supports life sciences organizations in bringing better therapies to market faster.

Our work has real, measurable impact. Genomenon's platforms and services are used by more than 250 clinical laboratories and pharma organizations worldwide to support diagnostic interpretation, variant curation, and evidence-based decision-making across the drug development lifecycle.

Each year, our technology helps inform care for tens of thousands of patients facing rare, complex, and time-sensitive conditions—reducing uncertainty and delivering answers when they matter most.

What makes Genomenon unique is our ability to support both clinical diagnostics and pharmaceutical innovation on a shared foundation of advanced AI, deep domain expertise, and rigorously curated data.

  • In the clinic, our solutions directly influence real world patient outcomes.
  • In pharma, we enable teams to harness literature derived RWE across clinical trial development, regulatory, and commercial workflows—turning fragmented biomedical knowledge into a strategic asset and emerging as the trusted data layer for genomic diagnostics and precision therapeutics.

If you're motivated by impact, energized by complexity, and excited to help shape the future of rare disease diagnosis and treatment, there's no better place to do that work.

Genomenon /ge.gno.mai.non/
Source language: ancient Greek
  1. Verb
    to come into being
    to be born out of need
  2. Noun
    the leader in genomic intelligence
Our Community

Genomenon team members are thoughtful, ambitious, and mission-driven professionals working across states and countries. Our team brings together scientists, clinicians, engineers, and commercial leaders who collaborate as equals and learn from one another every day.

We value curiosity, accountability, and people who thrive in fast-moving, high-impact environments.

We are guided by our core values:

  • Always Learning: Approach challenges with curiosity and a growth mindset
  • Data-Driven: Ask a lot of questions and look to the evidence for answers
  • Humbly Confident: Aware of the value that we and others bring to the team
  • Customer & Patient Driven: Put patients and customers first in everything we do
  • True Grit: Embody passion and persistence, and aren't afraid of hard work
Our Company

Genomenon is an AI-driven, genomics software company. Our mission is to save and improve lives by making genomic information actionable. We organize the world's genomic knowledge and put it at the fingertips of clinicians to help diagnose and treat patients suffering from rare diseases and cancer, and to help precision medicine companies create targeted therapies for diseases.

There are over 7,000 rare diseases affecting nearly 30 million Americans, 95% of which have no treatment. By harnessing AI and human insight, Genomenon's team is revolutionizing genetic medicine and leading a charge against genetic diseases and cancer for clinicians and pharmaceutical pioneers alike. And the adventure has just begun!

Join us in championing the spirit of Genomenon, where every data point is a beacon of hope, every insight a catalyst for change, and every person a vital thread in the fabric of progress.

/ge.gno.mai.non/
source language: ancient Greek
verb

  1. to come into being
  2. to be born out of need

noun

  1. the leader in Genomic Intelligence

At Genomenon, we are at the forefront of genomics research and innovation, with a mission to accelerate genetic discoveries and improve patient care.

Our Commitment

Building a great company starts with building a diverse and inclusive team. We believe that people with different backgrounds, perspectives, and life experiences help us solve harder problems and build better solutions.

Genomenon is committed to inclusion across race, gender, age, religion, identity, disability, and background — in how we hire, how we work, and how we lead.

If you're excited about the role but unsure whether you meet every qualification, we encourage you to apply. We'd rather review one more resume than miss the chance to meet someone exceptional.