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Sr Cra Jobs in Raleigh, NC (NOW HIRING)

Fortrea

Sr. CRA 2, FSP - Invitro Diagnostics

Durham, NC · On-site

$125 - $140K/hr

Our FSP team is currently seeking Sr. CRA 2s with 4+ years of monitoring residing in the East Coast, Midwest & West Coast US! WHAT YOU WILL DO You will utilize your skills, knowledge, and clinical ...

Veranex

Sr Clinical Research Associate

Raleigh, NC · On-site

$98K - $140K/yr

The Sr. CRA will participate in the planning, development, and execution of clinical trials to evaluate the safety, effectiveness and performance of medical devices. Under management supervision, the ...

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Sr Cra information

See Raleigh, NC salary details

$24.3K

$78K

$158.9K

How much do sr cra jobs pay per year?

As of Sep 2, 2026, the average yearly pay for sr cra in Raleigh, NC is $78,041.00, according to ZipRecruiter salary data. Most workers in this role earn between $40,300.00 and $100,100.00 per year, depending on experience, location, and employer.

What is a Senior Clinical Research Associate?

Senior Clinical Research Associates (Sr CRAs) are experienced professionals who oversee and monitor clinical trials to ensure they comply with regulatory requirements, protocols, and good clinical practice guidelines. They typically manage multiple study sites, conduct site visits, and act as a primary point of contact between the study sponsor and clinical sites. Sr CRAs also mentor junior CRAs, resolve complex issues, and ensure high-quality data collection and reporting. Their work is essential in bringing new drugs and medical devices to market safely and efficiently.

What are the key skills and qualifications needed to thrive as a Senior Clinical Research Associate?

To thrive as a Sr CRA, you need in-depth knowledge of clinical trial protocols, Good Clinical Practice (GCP) guidelines, and relevant regulatory requirements, typically backed by a degree in life sciences and significant monitoring experience. Familiarity with electronic data capture (EDC) systems, clinical trial management systems (CTMS), and certifications like ACRP or SOCRA are highly valued. Strong attention to detail, effective communication, and problem-solving skills distinguish top performers in this role. These skills ensure protocols are followed, data integrity is maintained, and studies are completed efficiently and compliantly.

What are some typical challenges faced by a Senior Clinical Research Associate when managing multiple clinical trial sites?

Senior Clinical Research Associates often juggle the oversight of several trial sites, which can pose challenges such as coordinating site schedules, ensuring consistent protocol compliance, and maintaining effective communication with site staff. Balancing documentation accuracy, regulatory requirements, and timely reporting is also crucial. Successful Sr CRAs develop strong organizational skills and proactive problem-solving approaches to address issues like site recruitment delays or data discrepancies, while also leveraging collaboration with project managers and clinical teams to keep trials on track.

What is the difference between Sr Cra vs Clinical Research Associate?

AspectSr CraClinical Research Associate
Required CredentialsBachelor's degree, experience in clinical trialsBachelor's degree, entry-level or some experience
Work EnvironmentSenior-level monitoring, site managementMonitoring sites, data collection
Employer & Industry UsagePharmaceutical companies, CROsPharmaceutical companies, CROs
Common Search & ComparisonHigher responsibility, leadership rolesEntry to mid-level monitoring

The main difference between a Sr Cra and a Clinical Research Associate is the level of experience and responsibility. A Sr Cra typically has more experience, handles complex site management, and may oversee other CRAs. In contrast, a Clinical Research Associate is often in an entry or mid-level role focused on site monitoring and data collection. Both roles are essential in clinical trials and are commonly found in pharmaceutical companies and CROs.

Is it hard to get a senior CRA job?

Securing a senior Clinical Research Associate (CRA) position typically requires several years of experience in clinical trials, strong knowledge of GCP guidelines, and relevant certifications such as CCRP or RAC. Competition can be high, but candidates with a proven track record in monitoring, site management, and regulatory compliance have better chances of obtaining such roles.

What are popular job titles related to Sr Cra jobs in Raleigh, NC?

For Sr Cra jobs in Raleigh, NC, the most frequently searched job titles are:

What job categories do people searching Sr Cra jobs in Raleigh, NC look for?

The top searched job categories for Sr Cra jobs in Raleigh, NC are:

What cities near Raleigh, NC are hiring for Sr Cra jobs?

Cities near Raleigh, NC with the most Sr Cra job openings:

Sr Cra jobs near you
Infographic showing various Sr Cra job openings in Raleigh, NC as of August 2026, with employment types broken down into 93% Full Time, 3% Part Time, and 4% Contract. Highlights an 82% Physical, 6% Hybrid, and 12% Remote job distribution, with an average salary of $78,041 per year, or $37.5 per hour.

CRA II & Sr. CRA - Ophthalmology & General Medicine

Fortrea

Durham, NC • On-site

$105/hr

Other

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 20 days ago

Fortrea rating

8.3

Company rating: 8.3 out of 10

Based on 11 frontline employees who took The Breakroom Quiz

27th of 74 rated research

Job description

We are currently seeking Experienced Ophthalmology (Sr CRAs & CRA 1/2) to lead and support our Full Service Outsourcing team. Open to major hub locations within the United States. 60-70% travel, 8-10 DOS per month.

WHAT YOU WILL DO

You will utilize your skills, knowledge, and clinical judgement to provide a high standard of care for participants in clinical trials and respond to emergency situations based upon clinical research standards.

Responsibilities:

  • Responsible for all aspects of study site monitoring including routine monitoring and close-out of clinical sites, maintenance of study files, conduct of pre-study and initiation visits; liaise with vendors; and other duties, as assigned -
  • Responsible for all aspects of site management as prescribed in the project plans
  • General On-Site Monitoring
  • Ensure the study staff who will conduct the protocol have received the proper materials and instructions to safely enter patients into the study
  • Ensure the protection of study patients by verifying that informed consent procedures and protocol requirements are adhered to according to the applicable regulatory requirements
  • Ensure the integrity of the data submitted on Case Report Forms (CRFs) or other data collection tools by careful source document Monitor data for missing or implausible data
  • Responsible for all aspects of registry management as prescribed in the project plans - Undertake feasibility work when requested
  • Complete Serious Adverse Event (SAE) reporting, process production of repo11s, narratives and follow up of SAEs
  • Independently perform CRF review; query generation and resolution against established data review guidelines on Fortrea or client data management systems as assigned by management
  • Assist with training of new employees, eg. co-monitoring
  • Coordinate designated clinical projects as a Local Project Coordinator (with supervision, ifapplicable) and may act as a local client contact as assigned
  • Perform other duties as assigned by management

Requirements

  • University or college degree, or certification in a related allied health profession from an appropriately accredited institution (e.g. nursing licensure)
  • 1-3 years of Clinical Monitoring experience
  • Open to various hub locations

The important thing for us is you are comfortable working in an environment that is:

  • Fast paced: where no deviations from the study protocol are allowed, and not meeting a timeline for even few minutes will create a quality issue.
  • Changing priorities constantly asking you to prioritize and adapt on the spot.
  • Teamwork and people skills are essential for the study to run smoothly.
  • Technology based. We collect our data directly into an electronic environment.

What do you get?

Regular, full-time or part-time employees working 20 or more hours per week are eligible for comprehensive benefits including but not limited to:

  • Medical, Dental, Vision, Life, STD/LTD (multiple insurance carriers)
  • 401(K)
  • Paid time off (PTO) - Flex Plan
  • Employee recognition awards
  • Multiple ERG's (employee resource groups)
  • Target Pay Range (based on title): $105-140K

Work Environment:

  • Work is performed in an office environment with exposure to electrical office equipment.
  • Frequent travel to clients/ site locations with occasional travel both domestic and international.

Physical Requirements:

  • Ability to sit for extended periods and operate a vehicle safely.
  • Repetitive hand movement of both hands with the ability to make fast, simple, repeated movements of the fingers, hands, and wrists.
  • Occasional crouching, stooping, with frequent bending and twisting of upper body and neck.
  • Ability to access and use a variety of computer software developed both in-house and off-the-shelf.
  • Light to moderate lifting and carrying (or otherwise moves) objects including luggage and laptop computer with a maximum lift of 15-20 lbs.
  • Regular and consistent attendance.
  • Varied hours may be required.

#LI - Remote

Applications will be accepted on an ongoing basis.

Learn more about our EEO & Accommodations request here.

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