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Sr Cra Jobs in Raleigh, NC (NOW HIRING)

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Senior CRA

Cary, NC · On-site

Senior CRA Phase I Oncology NC ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As a values ...

IQVIA, Inc.

CRA 2/Senior CRA

Durham, NC · On-site

$90K - $175K/yr

IQVIA Biotech is seeking CRA 2 and Sr. CRA 1 candidates with onsite monitoring experience in oncology. Join a Team That's Advancing Clinical Research We're looking for a passionate and driven ...

IQVIA

CRA 2/Senior CRA

Durham, NC · On-site

$90K - $175K/yr

IQVIA Biotech is seeking CRA 2 and Sr. CRA 1 candidates with onsite monitoring experience in oncology. Join a Team That's Advancing Clinical Research We're looking for a passionate and driven ...

IQVIA

CRA 2/Senior CRA

Durham, NC · On-site

$90K - $175K/yr

IQVIA Biotech is seeking CRA 2 and Sr. CRA 1 candidates with onsite monitoring experience in oncology. Join a Team That's Advancing Clinical Research We're looking for a passionate and driven ...

IQVIA, Inc.

CRA 2/Senior CRA

Durham, NC · On-site

$87K - $169K/yr

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

IQVIA

CRA 2/Senior CRA

Durham, NC

$87K - $169K/yr

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

IQVIA

CRA 2/Senior CRA

Durham, NC · On-site

$87K - $169K/yr

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

IQVIA, Inc.

CRA 2/Senior CRA 1

Durham, NC · On-site

$90K - $175K/yr

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

IQVIA

CRA 2/Senior CRA 1

Durham, NC · On-site

$90K - $175K/yr

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

IQVIA

CRA 2/Senior CRA 1

Durham, NC · On-site

$90K - $175K/yr

Join a Team That's Advancing Clinical Research We're looking for a passionate and driven Clinical Research Associate (CRA) to join our team and play a key role in delivering high-quality clinical ...

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Clinical Research Associate II

Raleigh, NC · Remote

Senior CRA / CRA II - United States - Home Based ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients ...

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Clinical Research Associate II

Raleigh, NC · Remote

Senior CRA / CRA II - United States - Home Based ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients ...

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Clinical Research Associate II

Cary, NC · Remote

Senior CRA / CRA II - United States - Home Based ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients ...

IQVIA

Clinical Research Associate

Durham, NC · On-site

$71K - $189K/yr

Clinical Research Associate II & Senior Clinical Research Associate (CRA II/Sr. CRA) Multiple Therapeutic Areas | Nationwide Opportunities IQVIA is actively seeking experienced Clinical Research ...

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All JobsSr Cra JobsSr Cra Jobs in Raleigh, NC

Sr Cra information

See Raleigh, NC salary details

$24.3K

$78K

$158.9K

How much do sr cra jobs pay per year?

As of Sep 2, 2026, the average yearly pay for sr cra in Raleigh, NC is $78,041.00, according to ZipRecruiter salary data. Most workers in this role earn between $40,300.00 and $100,100.00 per year, depending on experience, location, and employer.

What is a Senior Clinical Research Associate?

Senior Clinical Research Associates (Sr CRAs) are experienced professionals who oversee and monitor clinical trials to ensure they comply with regulatory requirements, protocols, and good clinical practice guidelines. They typically manage multiple study sites, conduct site visits, and act as a primary point of contact between the study sponsor and clinical sites. Sr CRAs also mentor junior CRAs, resolve complex issues, and ensure high-quality data collection and reporting. Their work is essential in bringing new drugs and medical devices to market safely and efficiently.

What are the key skills and qualifications needed to thrive as a Senior Clinical Research Associate?

To thrive as a Sr CRA, you need in-depth knowledge of clinical trial protocols, Good Clinical Practice (GCP) guidelines, and relevant regulatory requirements, typically backed by a degree in life sciences and significant monitoring experience. Familiarity with electronic data capture (EDC) systems, clinical trial management systems (CTMS), and certifications like ACRP or SOCRA are highly valued. Strong attention to detail, effective communication, and problem-solving skills distinguish top performers in this role. These skills ensure protocols are followed, data integrity is maintained, and studies are completed efficiently and compliantly.

What are some typical challenges faced by a Senior Clinical Research Associate when managing multiple clinical trial sites?

Senior Clinical Research Associates often juggle the oversight of several trial sites, which can pose challenges such as coordinating site schedules, ensuring consistent protocol compliance, and maintaining effective communication with site staff. Balancing documentation accuracy, regulatory requirements, and timely reporting is also crucial. Successful Sr CRAs develop strong organizational skills and proactive problem-solving approaches to address issues like site recruitment delays or data discrepancies, while also leveraging collaboration with project managers and clinical teams to keep trials on track.

What is the difference between Sr Cra vs Clinical Research Associate?

AspectSr CraClinical Research Associate
Required CredentialsBachelor's degree, experience in clinical trialsBachelor's degree, entry-level or some experience
Work EnvironmentSenior-level monitoring, site managementMonitoring sites, data collection
Employer & Industry UsagePharmaceutical companies, CROsPharmaceutical companies, CROs
Common Search & ComparisonHigher responsibility, leadership rolesEntry to mid-level monitoring

The main difference between a Sr Cra and a Clinical Research Associate is the level of experience and responsibility. A Sr Cra typically has more experience, handles complex site management, and may oversee other CRAs. In contrast, a Clinical Research Associate is often in an entry or mid-level role focused on site monitoring and data collection. Both roles are essential in clinical trials and are commonly found in pharmaceutical companies and CROs.

Is it hard to get a senior CRA job?

Securing a senior Clinical Research Associate (CRA) position typically requires several years of experience in clinical trials, strong knowledge of GCP guidelines, and relevant certifications such as CCRP or RAC. Competition can be high, but candidates with a proven track record in monitoring, site management, and regulatory compliance have better chances of obtaining such roles.

What are popular job titles related to Sr Cra jobs in Raleigh, NC?

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What job categories do people searching Sr Cra jobs in Raleigh, NC look for?

The top searched job categories for Sr Cra jobs in Raleigh, NC are:

What cities near Raleigh, NC are hiring for Sr Cra jobs?

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Sr Cra jobs near you
Infographic showing various Sr Cra job openings in Raleigh, NC as of August 2026, with employment types broken down into 93% Full Time, 3% Part Time, and 4% Contract. Highlights an 82% Physical, 6% Hybrid, and 12% Remote job distribution, with an average salary of $78,041 per year, or $37.5 per hour.

Senior CRA

Icon plc

Cary, NC • On-site

Full-time

Medical, Dental, Vision, Life, Retirement

Re-posted 8 days ago

Job description

Senior CRA Phase I Oncology NC

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.


As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.


As a Senior CRA at ICON Plc, you will oversee and manage clinical trial activities to ensure they are conducted according to protocol, regulatory requirements, and industry standards.

What You Will Do:

You will lead on clinical trial monitoring tasks requiring technical depth, with a focus on quality and continuous improvement.
Key responsibilities include:

  • Monitoring clinical trial sites to ensure adherence to study protocols, regulatory requirements, and Good Clinical Practice (GCP) standards.
  • Conducting site visits to assess site performance, resolve issues, and provide support to ensure successful trial execution.
  • Collaborating with cross-functional teams to ensure timely and accurate data collection and reporting.
  • Providing training and guidance to site staff and other CRAs to maintain high standards of clinical trial conduct.
  • Building and maintaining effective relationships with site personnel and stakeholders to facilitate smooth trial operations.

Your Profile:

You will have a strong foundation in clinical trial monitoring, with the experience to work independently and guide others.
Required qualifications and experience:

  • Bachelor's degree in a relevant scientific discipline or healthcare-related field
  • Extensive experience as a Clinical Research Associate, with a strong understanding of clinical trial processes and regulatory requirements.
  • Proven ability to manage multiple sites and projects simultaneously, with strong organizational and problem-solving skills.
  • Expertise in monitoring practices, data integrity, and site management, with proficiency in relevant clinical trial software and tools.
  • Excellent communication, interpersonal, and stakeholder management skills, with the ability to influence and drive compliance within a complex environment.
  • Willingness to travel as required (approximately 60%)

Employment with ICON is contingent upon having the legal right to work in the country where the role is based.


Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.


Benefits may include:

  • Competitive base salary and performance related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.


Visit our careers site to read more about the benefits ICON offers.


Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.


If you require reasonable accommodations during the recruitment process, please let us know or submit a requesthere.

Are you a current ICON Employee? Please click here to apply

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