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Sr Clinical Research Associate Jobs (NOW HIRING)

ICON

Senior Clinical Research Associate

Blue Bell, PA · On-site

We are currently seeking a Senior Clinical Research Associate or Clinical Research Associate II to join our diverse and dynamic team. As a Clinical Research Associate at ICON, you will play a pivotal ...

Icon plc

Senior Clinical Research Associate

Houston, TX · Hybrid

Contract Senior Clinical Research Associate - Home-Based (US) ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to ...

ICON

Senior Clinical Research Associate

Blue Bell, PA · On-site

ICON plc is seeking an experienced Senior Clinical Research Associate (Senior CRA) or Clinical Research Associate (CRA) to join our dynamic, collaborative team. In this role, you will be a key ...

ICON

Senior Clinical Research Associate

Blue Bell, PA · On-site

We are currently seeking a Contractor Senior Clinical Research Associate to join our diverse and dynamic team. This will be for a 6 month contract. As a Clinical Research Associate at ICON , you will ...

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Sr Clinical Research Associate information

See salary details

$36K

$94.3K

$143.5K

How much do sr clinical research associate jobs pay per year?

As of Jul 26, 2026, the average yearly pay for sr clinical research associate in the United States is $94,314.00, according to ZipRecruiter salary data. Most workers in this role earn between $62,500.00 and $128,000.00 per year, depending on experience, location, and employer.

What is the difference between Sr Clinical Research Associate vs Clinical Research Associate?

AspectSr Clinical Research AssociateClinical Research Associate
Required credentialsBachelor's degree, experience, often certifications like CCRP or RACBachelor's degree, entry-level or less experience, certifications optional
Work environmentPharmaceutical companies, CROs, clinical trial sitesSimilar settings, often entry-level roles in clinical trials
Employer and industry usageUsed in pharmaceutical and biotech industries, more senior rolesCommon in clinical research, entry to mid-level roles
Search and comparison intentOften searched for career progression or senior rolesOften searched for entry-level positions or understanding roles

The main difference between a Sr Clinical Research Associate and a Clinical Research Associate lies in experience, responsibilities, and qualifications. The senior role typically requires more experience, certifications, and involves overseeing complex trials, while the CRA is often an entry-level or mid-level position focused on supporting clinical trial activities.

What is a Sr Clinical Research Associate?

A Sr Clinical Research Associate (Senior CRA) is an experienced professional responsible for overseeing clinical trials to ensure they comply with regulatory requirements, protocols, and Good Clinical Practice (GCP) guidelines. They monitor study sites, review data, ensure participant safety, and act as a liaison between the sponsor and clinical sites. Senior CRAs often mentor junior staff, manage multiple studies, and contribute to improving clinical trial processes. Their role is vital in bringing new medical treatments and devices from research to market.

What are the key skills and qualifications needed to thrive as a Sr Clinical Research Associate, and why are they important?

To thrive as a Sr Clinical Research Associate, you need a robust background in clinical research, regulatory compliance, and study monitoring, usually supported by a bachelor's degree in life sciences and significant industry experience. Familiarity with electronic data capture (EDC) systems, Good Clinical Practice (GCP) guidelines, and certifications such as ACRP or SOCRA are highly valued. Outstanding attention to detail, strong organizational skills, and effective communication enable successful oversight of trial sites and collaboration with study teams. These skills are vital for ensuring the integrity, safety, and compliance of clinical trials, directly impacting study outcomes and regulatory approval.

What are some common challenges faced by a Sr Clinical Research Associate when monitoring multiple clinical trial sites?

As a Sr Clinical Research Associate (CRA), juggling multiple trial sites can be challenging due to varying site compliance levels, differing investigator engagement, and diverse patient populations. You may encounter issues such as inconsistent data entry, protocol deviations, and varying levels of site staff training. Effective time management, strong communication skills, and a proactive approach to problem-solving are essential to ensure all sites adhere to protocols and timelines. Additionally, frequent travel and adapting to each site's workflow can add complexity, but these challenges also provide valuable opportunities for professional growth.
More about Sr Clinical Research Associate jobs
What cities are hiring for Sr Clinical Research Associate jobs? Cities with the most Sr Clinical Research Associate job openings:
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Sr Clinical Research Associate jobs near you
Infographic showing various Sr Clinical Research Associate job openings in the United States as of July 2026, with employment types broken down into 1% As Needed, 69% Full Time, 28% Part Time, 1% Temporary, and 1% Contract. Highlights an 97% Physical, 1% Hybrid, and 2% Remote job distribution, with an average salary of $94,314 per year, or $45.3 per hour.

Senior Clinical Research Associate

410 ICR United States USA

United, PA • Remote

Full-time

Posted 29 days ago

Job description

Senior CRA/ CRA II

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.


As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.


We are currently seeking a Senior Clinical Research Associate or Clinical Research Associate II to join our diverse and dynamic team. As a Clinical Research Associate at ICON, you will play a pivotal role in designing and analyzing clinical trials, interpreting complex medical data, and contributing to the advancement of innovative treatments and therapies.

What you will be doing

  • Conducting site qualification, initiation, monitoring, and close-out visits for clinical trials.

  • Ensuring protocol compliance, data integrity, and patient safety throughout the trial process.

  • Collaborating with investigators and site staff to facilitate smooth study conduct.

  • Performing data review and resolution of queries to maintain high-quality clinical data.

  • Contributing to the preparation and review of study documentation, including protocols and clinical study reports


Your profile

  • Bachelor’s degree in a scientific or health-related field or an equivalent combination of education and clinical research experience, particularly in a study coordinator or nursing role

  • Minimum of 1 year independent monitoring to be considered for a Clinical Research Associate II and a minimum of 3 years independent monitoring to be considered for a Senior Clinical Research Associate.

  • In-depth knowledge of clinical trial processes, regulations, and ICH-GCP guidelines.

  • Strong organizational and communication skills, with attention to detail.

  • Ability to work independently and collaboratively in a fast-paced environment.

  • Ability to travel at least 60% of the time (international and domestic - fly and drive) and should possess a valid driver’s license

#LI-ZH1

#LI-REMOTE


Employment with ICON is contingent upon having the legal right to work in the country where the role is based.


Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.


Benefits may include:

  • Competitive base salary and performance related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.


Visit our careers site to read more about the benefits ICON offers.


Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.


If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.

Are you a current ICON Employee? Please click here to apply