ZipRecruiter

Log In

1

Clinical Research Site Manager Jobs (NOW HIRING)

ACRC Trials

Clinical Research Site Manager

Plano, TX · On-site

Role Overview We are seeking an experienced Clinical Research Site Manager to oversee daily operations across one or more research sites. This role is responsible for ensuring protocol compliance ...

next page

Showing results 1-20

All JobsClinical Research Site JobsClinical Research Site Manager Jobs

Clinical Research Site Manager information

See salary details

$49K

$107.3K

$189K

How much do clinical research site manager jobs pay per year?

As of Aug 7, 2026, the average yearly pay for clinical research site manager in the United States is $107,336.00, according to ZipRecruiter salary data. Most workers in this role earn between $81,000.00 and $122,500.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a clinical research site manager?

To thrive as a Clinical Research Site Manager, you need a solid background in clinical research, regulatory compliance, and project management, often supported by a bachelor’s or master’s degree in a health-related field. Familiarity with clinical trial management systems (CTMS), Good Clinical Practice (GCP) guidelines, and regulatory documentation is crucial. Strong leadership, organizational, and communication skills help you coordinate teams, manage timelines, and foster productive sponsor relationships. These skills and qualities are vital for ensuring clinical trial integrity, regulatory adherence, and successful study outcomes.

What are some common challenges faced by clinical research site managers, and how can they be addressed?

Clinical Research Site Managers often encounter challenges such as balancing multiple studies simultaneously, ensuring regulatory compliance, and maintaining participant recruitment targets. Managing communication between sponsors, investigators, and clinical staff can also be complex, especially when timelines are tight. These challenges are typically addressed by implementing strong organizational systems, fostering open communication among team members, and staying updated with regulatory changes through ongoing training.

What does a clinical research site manager do?

A Clinical Research Site Manager is responsible for overseeing the daily operations of clinical trials conducted at a research site. They ensure that studies are conducted in compliance with regulatory guidelines, manage site staff, coordinate with sponsors and monitors, and maintain accurate documentation. Their work is crucial for ensuring patient safety, data integrity, and the successful completion of clinical research studies.

What is the difference between Clinical Research Site Manager vs Clinical Research Coordinator?

AspectClinical Research Site ManagerClinical Research Coordinator
CredentialsBachelor's degree; often experience in clinical settingsBachelor's degree; relevant certifications often preferred
Work EnvironmentOversees entire research site operationsAssists with patient recruitment, data collection, and study procedures
Employer & Industry UsageResearch institutions, pharmaceutical companies, CROsHospitals, clinics, research sites

The Clinical Research Site Manager typically oversees the entire research site, managing staff and operations, while the Clinical Research Coordinator focuses on day-to-day study activities and participant coordination. Both roles require relevant experience and certifications, but the Site Manager has broader responsibilities in leadership and site management.

More about Clinical Research Site Manager jobs
What cities are hiring for Clinical Research Site Manager jobs? Cities with the most Clinical Research Site Manager job openings:
What states have the most Clinical Research Site Manager jobs? States with the most job openings for Clinical Research Site Manager jobs include:
What job categories do people searching Clinical Research Site Manager jobs look for? The top searched job categories for Clinical Research Site Manager jobs are:
Clinical Research Site Manager jobs near you
Infographic showing various Clinical Research Site Manager job openings in the United States as of August 2026, with employment types broken down into 88% Full Time, 11% Part Time, and 1% Contract. Highlights an 85% Physical, 2% Hybrid, and 13% Remote job distribution, with an average salary of $107,336 per year, or $51.6 per hour.

Clinical Research Site Manager

Alcanza Clinical Research

Fredericksburg, VA • On-site

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 18 days ago

Job description

Clinical Research Site Manager
Department: Operations
Employment Type: Full Time
Location: Fredericksburg Clinical Research
Reporting To: Hollis Ryan
Description
Alcanza is a growing multi-site, multi-phase clinical research company with a network of locations in AL, AZ, FL, GA, IL, MA, MI, MO, NV, VA, SC, TN, TX and Puerto Rico. We have established a strong presence across Phase I-IV studies and several therapeutic areas including vaccine, neurology, dermatology, psychiatry, and general medicine. Join us as we continue to grow.
The Clinical Site Manager is responsible for overseeing performance of the research site activities. Provides on-site oversight to help ensure execution and coordination of clinical research activities visits, documentation and follow up actions according to ICH/FDA guidelines, GCP, and company SOPs, policies and procedures.
Key Responsibilities
Essential Job Duties:
  • Overall site management and leadership with a focus on driving site performance, enhancing efficiencies, patient safety and protocol/GCP/regulatory compliance;
  • Collaborating with manager to support delivery expectations, meet expected study milestones (such as site activation targets, enrollment targets, etc.), meet budgets, and delivery quality data to sponsors;
  • Overseeing resourcing allocations, site assignments and study team members' output and performance, to ensure study deliverables are on track, identifying risks to delivery or quality, and escalating any risks to clinical trial management deliverables (timeline, quality and budget);
  • Reviewing the performance dashboards and other clinical trial systems to oversee site and patient activities, ensure proper staff coverage, and to ensure the data has been updated to reflect timely execution of all operational aspects (required visits/calls, duration, and frequency);
  • Ensuring adherence to standard operating procedures, good clinical practice (GCP), FDA regulations, and company policies and procedures;
  • Overseeing site staff assigned to the study and routinely assessing study-specific process and training compliance, CMP compliance, and identifies emerging risks. May develop and support execution of corrective action plans at site and study level;
  • Overseeing people management activities including timecards, absence tracking/approvals, new hire training, interviewing and selection, performance appraisals, job description preparation, employee counseling, career coaching and termination meetings.
  • Managing assigned site staff, proactively identify and resolve issues, and work to ensure successful site operations;
  • Assisting with initial and ongoing trainings regarding protocol specificities, Case Report Form (CRF) completion, Standard Operating Procedures (SOPs), clinical plans and guidelines, and timelines for the study;
  • Collaborating with investigators to ensure patient safety and meeting client goals and timelines;
  • Employing problem-solving skills to propose and implement risk mitigations;
  • Participating and presenting in management or site meetings;
  • Perform all other duties as required or assigned.

Skills, Knowledge and Expertise
Minimum Qualifications: An Associate's degree and a minimum of 3 years of clinical research experience, or an equivalent combination of education and experience, is required. One or more years of management experience is highly preferred. Bi-lingual (English / Spanish) proficiency is a plus.
Required Skills:
  • Proficiency with computer applications such as Microsoft applications, email, electronic health records, web applications, and the ability to type proficiently (40+ wpm).
  • Must possess strong organizational, time management and problem solving skills.
  • Well-developed written and verbal communication skills.
  • Well-developed interpersonal and listening skills and the ability to work well independently as well as with co-workers, subjects, managers and external customers.
  • Ability to effectively handle multiple tasks, and adapt to changes in workloads and priorities.
  • Must be professional, respectful of others, self-motivated, and have a strong work ethic.
  • Must possess a high degree of integrity and dependability.
  • Ability to work under minimal supervision, identify problems and implement solutions.
  • Ability to handle highly sensitive information in a confidential and professional manner, and in compliance with HIPAA guidelines.

Benefits
  • Full-time employees regularly scheduled to work at least 30 hours per week are benefits-eligible, with coverage starting on the first day of the month following date of hire.
  • Medical, dental, vision, life insurance, short and long-term disability insurance, health savings accounts, supplemental insurances, and a 401k plan with a safe harbor match are offered.

Apply