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Clinical Research Site Manager Jobs (NOW HIRING)

Iterative Health

Research Site Manager

Orlando, FL · On-site

By combining deep clinical trial expertise with cutting-edge AI, we connect sponsors' scientific ... The Research Site Manager at Iterative Health is the operational backbone of our clinical research ...

MD Ally

Research Site Manager

Southlake, TX · On-site

$70 - $90/hr

By combining deep clinical trial expertise with cutting-edge AI, we connect sponsors' scientific ... The Research Site Manager at Iterative Health is the operational backbone of our clinical research ...

jobr.pro

Research Site Manager

Southlake, TX · On-site

$75 - $95/hr

By combining deep clinical trial expertise with cutting-edge AI, we connect sponsors' scientific ... The Research Site Manager at Iterative Health is the operational backbone of our clinical research ...

MD Ally

Research Site Manager

Orlando, FL · On-site

$85 - $120/hr

By combining deep clinical trial expertise with cutting-edge AI, we connect sponsors' scientific ... The Research Site Manager at Iterative Health is the operational backbone of our clinical research ...

Iterative Health

Research Site Manager

Orlando, FL · On-site

By combining deep clinical trial expertise with cutting-edge AI, we connect sponsors' scientific ... The Research Site Manager at Iterative Health is the operational backbone of our clinical research ...

Alcanza

Clinical Research Site Director

Orlando, FL · On-site

Overall site management and leadership with a focus on driving site performance, enhancing ... A Bachelor's degree AND 5+ years of clinical research experience or an equivalent combination of ...

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Clinical Research Site Manager information

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$49K

$107.3K

$189K

How much do clinical research site manager jobs pay per year?

As of Aug 28, 2026, the average yearly pay for clinical research site manager in the United States is $107,336.00, according to ZipRecruiter salary data. Most workers in this role earn between $81,000.00 and $122,500.00 per year, depending on experience, location, and employer.

What does a clinical research site manager do?

A Clinical Research Site Manager is responsible for overseeing the daily operations of clinical trials conducted at a research site. They ensure that studies are conducted in compliance with regulatory guidelines, manage site staff, coordinate with sponsors and monitors, and maintain accurate documentation. Their work is crucial for ensuring patient safety, data integrity, and the successful completion of clinical research studies.

What are the key skills and qualifications needed to thrive as a clinical research site manager?

To thrive as a Clinical Research Site Manager, you need a solid background in clinical research, regulatory compliance, and project management, often supported by a bachelor’s or master’s degree in a health-related field. Familiarity with clinical trial management systems (CTMS), Good Clinical Practice (GCP) guidelines, and regulatory documentation is crucial. Strong leadership, organizational, and communication skills help you coordinate teams, manage timelines, and foster productive sponsor relationships. These skills and qualities are vital for ensuring clinical trial integrity, regulatory adherence, and successful study outcomes.

What are some common challenges faced by clinical research site managers, and how can they be addressed?

Clinical Research Site Managers often encounter challenges such as balancing multiple studies simultaneously, ensuring regulatory compliance, and maintaining participant recruitment targets. Managing communication between sponsors, investigators, and clinical staff can also be complex, especially when timelines are tight. These challenges are typically addressed by implementing strong organizational systems, fostering open communication among team members, and staying updated with regulatory changes through ongoing training.

What is the difference between Clinical Research Site Manager vs Clinical Research Coordinator?

AspectClinical Research Site ManagerClinical Research Coordinator
CredentialsBachelor's degree; often experience in clinical settingsBachelor's degree; relevant certifications often preferred
Work EnvironmentOversees entire research site operationsAssists with patient recruitment, data collection, and study procedures
Employer & Industry UsageResearch institutions, pharmaceutical companies, CROsHospitals, clinics, research sites

The Clinical Research Site Manager typically oversees the entire research site, managing staff and operations, while the Clinical Research Coordinator focuses on day-to-day study activities and participant coordination. Both roles require relevant experience and certifications, but the Site Manager has broader responsibilities in leadership and site management.

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What cities are hiring for Clinical Research Site Manager jobs?

Cities with the most Clinical Research Site Manager job openings:

What states have the most Clinical Research Site Manager jobs?

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What job categories do people searching Clinical Research Site Manager jobs look for?

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Clinical Research Site Manager jobs near you
Infographic showing various Clinical Research Site Manager job openings in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $107,336 per year, or $51.6 per hour.

Site Manager (Clinical Trials Facility)

Merrillville, IN • On-site

Protouch Staffing
Recruiting and Staffing Services • 51 - 200 employees
Learn more about Protouch Staffingexternal

$95K - $110K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 10 days ago

Job description

Clinical Research Site Manager

(Lead CRC or Senior CRC with Management Experience)

Location: Merrillville, IN

Job Type: Full-Time

Schedule: Monday-Friday (5x8 shifts)

Salary Range: $95K to $110K + Profit Distribution


Position Summary

The Clinical Research Site Manager is responsible for overseeing the daily operations of the clinical research site, ensuring strict protocol compliance, high-quality patient care, and seamless coordination with sponsors and CROs. This role leads site staff, monitors study performance, and ensures adherence to regulatory and ethical standards.


Key Responsibilities

  • Oversee daily site operations and ensure compliance with GCP, FDA, and ICH guidelines

  • Supervise and support Clinical Research Coordinators (CRCs), nurses, and clinical staff

  • Serve as the primary point of contact for sponsors, CROs, and monitors

  • Oversee patient recruitment, informed consent, and retention strategies

  • Ensure accurate data entry and timely resolution of data queries

  • Manage study budgets, contracts, and allocation of site resources

  • Maintain regulatory documentation and audit readiness


Qualifications

  • Bachelor's degree in Life Sciences, Nursing, or related field (Master's preferred)

  • 3-5 years of clinical research experience

  • 1-2 years of leadership or site management experience

  • Strong working knowledge of GCP, FDA, and ICH regulations

  • Excellent leadership, communication, and organizational skills


Benefits

  • Health, Dental, and Vision Insurance

  • Paid Time Off (PTO)

  • Retirement Plan

  • Profit Distribution

Protouch Staffing logo

About Protouch Staffing

Sourced by ZipRecruiter

Protouch Staffing, based in Plano, Texas, is a leading provider in the healthcare staffing industry. Established over 30 years ago, the company prides itself on delivering quality services in the fields of nursing, allied health, pharmaceuticals, healthcare IT, and more. Committed to building lasting relationships, Protouch Staffing continually exceeds client expectations by providing unparalleled service, superior patient care, and talented healthcare professionals.

Industry

Recruiting and staffing services

Company size

51 - 200 Employees

Headquarters location

Frisco, TX, US

Year founded

1989

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