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Senior Clinical Research Associate Jobs (NOW HIRING)

ICON

Senior Clinical Research Associate

Blue Bell, PA · On-site

We are currently seeking a Senior Clinical Research Associate or Clinical Research Associate II to join our diverse and dynamic team. As a Clinical Research Associate at ICON, you will play a pivotal ...

ICON

Senior Clinical Research Associate

Blue Bell, PA · On-site

We are currently seeking a Contractor Senior Clinical Research Associate to join our diverse and dynamic team. This will be for a 6 month contract. As a Clinical Research Associate at ICON , you will ...

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Senior Clinical Research Associate

Chicago, IL · Hybrid

$110K - $138K/yr

Senior Clinical Research Associate - Oncology Phase I - Chicago ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments ...

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Senior Clinical Research Associate

Denver, CO · Hybrid

$110K - $138K/yr

Senior Clinical Research Associate - Oncology Phase I - Denver, CO ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and ...

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Senior Clinical Research Associate

San Diego, CA · Hybrid

$110K - $138K/yr

Senior Clinical Research Associate - Oncology - Southern California ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and ...

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$36K

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How much do senior clinical research associate jobs pay per year?

As of Aug 13, 2026, the average yearly pay for senior clinical research associate in the United States is $94,314.00, according to ZipRecruiter salary data. Most workers in this role earn between $62,500.00 and $128,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a senior clinical research associate, and why are they important?

To thrive as a Senior Clinical Research Associate, you need a solid background in clinical research, regulatory compliance, and often a degree in life sciences or a related field. Familiarity with electronic data capture (EDC) systems, Good Clinical Practice (GCP) guidelines, and relevant certifications such as ACRP or SOCRA are typically required. Strong organizational skills, attention to detail, and the ability to communicate effectively with diverse stakeholders make someone stand out in this position. These skills and qualities are vital for ensuring studies are conducted ethically, accurately, and in compliance with regulatory standards.

What does a senior clinical research associate do?

A senior clinical research associate (CRA) monitors clinical trials and manages team members. Your duties include leading project team meetings, running experiments, making observations, tracking results, and analyzing data. You also ensure experiments meet all clinical practice and safety standards. Qualifications for this career are a bachelor of science in a biomedical field or a bachelor of science in nursing (BSN), along with professional experience in a medical or research setting. You must have strong communication, interpersonal, leadership, and technical writing skills.

What are some typical challenges faced by senior clinical research associates when overseeing multiple clinical trials?

Senior Clinical Research Associates (SCRAs) often manage several studies at once, which requires balancing competing deadlines, ensuring protocol compliance, and maintaining strong communication with site staff. A common challenge is ensuring consistent data quality and regulatory adherence across diverse sites, especially when trials are geographically dispersed. Effective time management, attention to detail, and proactive problem-solving are crucial for success in this role. Collaboration with project managers, investigators, and regulatory teams is also essential to ensure trials progress smoothly and meet all regulatory requirements.
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Senior Clinical Research Associate jobs near you
Infographic showing various Senior Clinical Research Associate job openings in the United States as of August 2026, with employment types broken down into 3% As Needed, 72% Full Time, 17% Part Time, and 8% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $94,314 per year, or $45.3 per hour.

Senior Clinical Research Associate

410 ICR United States USA

United, PA • Remote

Full-time

Re-posted 17 days ago

Job description

Senior CRA / CRA II - Home-Based (United States)

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.


As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.


We are currently seeking a Senior Clinical Research Associate or Clinical Research Associate II to join our diverse and dynamic team. As a Clinical Research Associate at ICON, you will play a pivotal role in designing and analyzing clinical trials, interpreting complex medical data, and contributing to the advancement of innovative treatments and therapies.

What you will be doing

  • Conducting site qualification, initiation, monitoring, and close-out visits for clinical trials.

  • Ensuring protocol compliance, data integrity, and patient safety throughout the trial process.

  • Collaborating with investigators and site staff to facilitate smooth study conduct.

  • Performing data review and resolution of queries to maintain high-quality clinical data.

  • Contributing to the preparation and review of study documentation, including protocols and clinical study reports


Your profile

  • Bachelor's degree, or its international equivalent in a scientific or health-related field or an equivalent combination of education and clinical research experience, particularly in a study coordinator or nursing role

  • Minimum of 1 year independent monitoring to be considered for a Clinical Research Associate II and a minimum of 3 years independent monitoring to be considered for a Senior Clinical Research Associate.

  • In-depth knowledge of clinical trial processes, regulations, and ICH-GCP guidelines.

  • Strong organizational and communication skills, with attention to detail.

  • Ability to work independently and collaboratively in a fast-paced environment.

  • Ability to travel at least 60% of the time (international and domestic - fly and drive) and should possess a valid driver’s license

#LI-KC2 #LI-REMOTE


Employment with ICON is contingent upon having the legal right to work in the country where the role is based.


Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.


Benefits may include:

  • Competitive base salary and performance related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.


Visit our careers site to read more about the benefits ICON offers.


Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.


If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.

Are you a current ICON Employee? Please click here to apply