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Senior Python Developer Jobs in Charlotte, NC (NOW HIRING)

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Power BI Developer

Charlotte, NC · On-site

* Senior AI Data Analytics and Automation Lead Role Summary: * Client is seeking a highly skilled and ... The ideal candidate combines deep expertise in Power BI, Excel, Python, and data engineering with a ...

GreyStar Systems LLC

Sr. Software Engineer

Charlotte, NC · On-site

$119K - $157K/yr

Strong backend Python developer with proven experience delivering AI-driven solutions. Candidates with both Full Stack and AI engineering expertise will be given preference. Experience building ...

ApTask

Senior UiPath Developer

Charlotte, NC · On-site

$93K - $128K/yr

They are seeking a Senior UiPath Developer to take ownership of in-house utility development, AI/ML ... NET Core • Python (API integration, data transformation, ML utilities) • Kafka • Develop ...

Delan Associates, Inc

Senior .NET Developer

Charlotte, NC

$53.75 - $68.25/hr

Senior .NET Developer Location: Charlotte, NC (Onsite) - Multiple Roles Employment: W2 Experience ... Python knowledge or willingness to learn * Investment Banking (Risk/Product) experience * Agile ...

Delan Associates, Inc

Senior .NET Developer

Charlotte, NC · On-site

$53.75 - $68.25/hr

Senior .NET Developer Location: Charlotte, NC (Onsite) - Multiple Roles Employment: W2 Experience ... Python knowledge or willingness to learn * Investment Banking (Risk/Product) experience * Agile ...

Delan Associates, Inc.

Senior .NET Developer

Charlotte, NC · On-site

$53.75 - $68.25/hr

Senior .NET Developer Location: Charlotte, NC (Onsite) - Multiple Roles Employment: W2 Experience ... Python knowledge or willingness to learn * Investment Banking (Risk/Product) experience * Agile ...

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All JobsPython Developer JobsSenior Python Developer JobsSenior Python Developer Jobs in Charlotte, NC

Senior Python Developer information

See Charlotte, NC salary details

$53.7K

$138.7K

$190.5K

How much do senior python developer jobs pay per year?

As of Aug 18, 2026, the average yearly pay for senior python developer in Charlotte, NC is $138,670.00, according to ZipRecruiter salary data. Most workers in this role earn between $118,700.00 and $159,700.00 per year, depending on experience, location, and employer.

What are the main responsibilities of a senior Python developer?

A Senior Python Developer is responsible for designing, developing, and maintaining complex software applications using the Python programming language. They lead the technical aspects of projects, mentor junior developers, and ensure code quality through code reviews and best practices. Additionally, they collaborate with cross-functional teams to gather requirements, solve technical challenges, and deploy scalable and efficient solutions. Senior Python Developers are also expected to stay updated with the latest trends and advancements in Python and related technologies.

What are the key skills and qualifications needed to thrive as a senior Python developer?

To thrive as a Senior Python Developer, you need advanced proficiency in Python programming, experience with software architecture, and a solid understanding of algorithms and data structures, usually backed by a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and containerization tools like Docker are typically required, alongside knowledge of modern CI/CD pipelines. Strong problem-solving abilities, effective communication, and leadership skills help you collaborate with teams and mentor junior developers. Mastery of these skills ensures the delivery of scalable, maintainable software solutions and the ability to drive technical excellence within development teams.

What are some common challenges faced by senior Python developers when leading a development team?

Senior Python Developers often encounter challenges such as balancing hands-on coding with mentoring junior team members and ensuring code quality across the team. They are also responsible for making architectural decisions, which requires staying updated on best practices and emerging Python frameworks. Additionally, coordinating collaboration between cross-functional teams (like DevOps, QA, and front-end developers) can be complex, especially in agile environments where requirements may shift rapidly. Overcoming these challenges helps foster a productive and innovative team culture.

What is the difference between Senior Python Developer vs Python Developer?

AspectSenior Python DeveloperPython Developer
Required ExperienceTypically 5+ years, with leadership and complex project experienceUsually 1-3 years, focusing on core Python skills
ResponsibilitiesDesigning architecture, mentoring, handling complex systemsWriting code, debugging, implementing features
CertificationsOptional but beneficial (e.g., Python certifications, cloud certs)Often not required
Work EnvironmentCollaborative teams, project planning, code reviewsDevelopment-focused, task-oriented

The main difference between a Senior Python Developer and a Python Developer lies in experience, responsibilities, and leadership. Senior developers handle complex projects, mentor others, and often participate in architecture decisions, while Python Developers focus on coding and feature implementation. Both roles are essential in tech companies, but the senior role requires more experience and broader skills.

Are senior Python developers still in demand?

Senior Python developers remain in high demand due to the language's versatility in web development, data analysis, machine learning, and automation. Companies seek experienced developers with skills in frameworks like Django or Flask, and proficiency in cloud platforms and APIs enhances job prospects.

How much does a senior Python developer make?

A senior Python developer typically earns between $100,000 and $150,000 annually, depending on experience, location, and industry. They often possess strong skills in frameworks like Django or Flask and may hold certifications or advanced degrees that influence salary levels.

What does a senior Python developer do?

A senior Python developer designs, develops, and maintains complex software applications using Python. They often lead projects, review code, optimize performance, and collaborate with cross-functional teams, requiring strong problem-solving skills and knowledge of frameworks like Django or Flask. Additionally, they may mentor junior developers and ensure code quality through testing and best practices.

What are the most commonly searched types of Python Developer jobs in Charlotte, NC?

The most popular types of Python Developer jobs in Charlotte, NC are:

What are popular job titles related to Senior Python Developer jobs in Charlotte, NC?

For Senior Python Developer jobs in Charlotte, NC, the most frequently searched job titles are:

What job categories do people searching Senior Python Developer jobs in Charlotte, NC look for?

The top searched job categories for Senior Python Developer jobs in Charlotte, NC are:

What cities near Charlotte, NC are hiring for Senior Python Developer jobs?

Cities near Charlotte, NC with the most Senior Python Developer job openings:

Senior Python Developer jobs near you
Infographic showing various Senior Python Developer job openings in Charlotte, NC as of August 2026, with employment types broken down into 1% Internship, 85% Full Time, 8% Part Time, and 6% Contract. Highlights an 79% Physical, 6% Hybrid, and 15% Remote job distribution, with an average salary of $138,670 per year, or $66.7 per hour.

Sr AI Developer/Agentic AI Engineer

Accord Technologies Inc.

Charlotte, NC • On-site

Contractor

Re-posted 8 days ago

Job description

Title: AI developer/Agentic AI Engineer
Location: Charlotte, NC
Duration: 12 months
Position type: W2 contract
 

Job Description :

We are seeking for highly skilled Software Engineer with strong expertise in modern Python development and Large Language Model (LLM) ecosystems.
This role focuses on building scalable, production-grade AI systems, leveraging advanced API development, retrieval-augmented generation (RAG), and agentic frameworks. 
You will work on cutting-edge AI solutions, contributing to the design, development, and deployment of intelligent systems within a distributed enterprise environment

Core Programming & Backend Development

  • Develop robust, scalable applications using Python (intermediate to advanced level)

  • Implement asynchronous programming patterns for high-performance systems

  • Design and build RESTful APIs using FastAPI

  • Write clean, maintainable, production-grade code

  • Develop and execute unit and integration tests

  • Debug and resolve issues in complex distributed systems

LLM Fundamentals & Prompt Engineering

  • Design and optimize prompts for various LLM use cases

  • Understand tokenization, context windows, and model limitations

  • Select appropriate models based on performance and cost trade-offs

  • Mitigate hallucinations and ensure grounded, reliable responses

Retrieval-Augmented Generation (RAG)

  • Build and maintain document ingestion and preprocessing pipelines

  • Implement chunking strategies (semantic, recursive, sliding window)

  • Generate and manage embeddings

  • Work with vector databases (e.g., pgvector)

  • Design hybrid search systems combining keyword (BM25) and semantic search

  • Optimize re-ranking and relevance tuning mechanisms

Agentic Frameworks & Orchestration

  • Design and implement multi-agent systems

  • Manage conversational and long-term memory

  • Build workflow orchestration pipelines for AI agents

Required Qualifications

  • Strong proficiency in Python with experience in asynchronous programming

  • Hands-on experience with FastAPI or similar frameworks

  • Experience building scalable backend systems

  • Solid understanding of LLM concepts and prompt engineering

  • Experience with RAG pipelines and vector databases (pgvector preferred)

  • Familiarity with distributed systems and debugging techniques

  • Experience with Docker and CI/CD pipelines