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Senior Python Developer Jobs in Durham, NC (NOW HIRING)

Compunnel

Senior Python Developer

Durham, NC · On-site

$117K - $158K/yr

Job Summary The Senior Python Developer is responsible for designing, developing, and maintaining mission-critical enterprise applications with a strong focus on backend development, API integrations ...

ACA Group

Python/AI Product Engineer

Durham, NC · On-site

Position Overview We are seeking a highly experienced Senior / Lead AI Developer to join our ... OR Pittsburgh The ideal candidate has deep expertise in Python development, distributed cloud ...

ACA Group

Python/AI Product Engineer

Durham, NC · Hybrid

Position Overview We are seeking a highly experienced Senior / Lead AI Developer to join our ... OR Pittsburgh The ideal candidate has deep expertise in Python development, distributed cloud ...

Compunnel

Senior Data Scientist Level-2

Raleigh, NC · On-site

JOB SUMMARY Senior Data Scientist II will leverage advanced analytical skills to extract insights ... Experience with coding skills in Python or another programming language. Be experienced in ...

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All JobsPython Developer JobsSenior Python Developer JobsSenior Python Developer Jobs in Durham, NC

Senior Python Developer information

See Durham, NC salary details

$49.8K

$128.6K

$176.7K

How much do senior python developer jobs pay per year?

As of Aug 10, 2026, the average yearly pay for senior python developer in Durham, NC is $128,639.00, according to ZipRecruiter salary data. Most workers in this role earn between $110,100.00 and $148,100.00 per year, depending on experience, location, and employer.

What are the main responsibilities of a senior Python developer?

A Senior Python Developer is responsible for designing, developing, and maintaining complex software applications using the Python programming language. They lead the technical aspects of projects, mentor junior developers, and ensure code quality through code reviews and best practices. Additionally, they collaborate with cross-functional teams to gather requirements, solve technical challenges, and deploy scalable and efficient solutions. Senior Python Developers are also expected to stay updated with the latest trends and advancements in Python and related technologies.

What is the difference between Senior Python Developer vs Python Developer?

AspectSenior Python DeveloperPython Developer
Required ExperienceTypically 5+ years, with leadership and complex project experienceUsually 1-3 years, focusing on core Python skills
ResponsibilitiesDesigning architecture, mentoring, handling complex systemsWriting code, debugging, implementing features
CertificationsOptional but beneficial (e.g., Python certifications, cloud certs)Often not required
Work EnvironmentCollaborative teams, project planning, code reviewsDevelopment-focused, task-oriented

The main difference between a Senior Python Developer and a Python Developer lies in experience, responsibilities, and leadership. Senior developers handle complex projects, mentor others, and often participate in architecture decisions, while Python Developers focus on coding and feature implementation. Both roles are essential in tech companies, but the senior role requires more experience and broader skills.

How much does a senior Python developer make?

A senior Python developer's salary typically ranges from $100,000 to $150,000 annually, depending on experience, location, and industry. They often possess strong skills in frameworks like Django or Flask and may have certifications or experience with cloud platforms, which can influence compensation.

What are the key skills and qualifications needed to thrive as a senior Python developer?

To thrive as a Senior Python Developer, you need advanced proficiency in Python programming, experience with software architecture, and a solid understanding of algorithms and data structures, usually backed by a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and containerization tools like Docker are typically required, alongside knowledge of modern CI/CD pipelines. Strong problem-solving abilities, effective communication, and leadership skills help you collaborate with teams and mentor junior developers. Mastery of these skills ensures the delivery of scalable, maintainable software solutions and the ability to drive technical excellence within development teams.

What are some common challenges faced by senior Python developers when leading a development team?

Senior Python Developers often encounter challenges such as balancing hands-on coding with mentoring junior team members and ensuring code quality across the team. They are also responsible for making architectural decisions, which requires staying updated on best practices and emerging Python frameworks. Additionally, coordinating collaboration between cross-functional teams (like DevOps, QA, and front-end developers) can be complex, especially in agile environments where requirements may shift rapidly. Overcoming these challenges helps foster a productive and innovative team culture.
What are the most commonly searched types of Python Developer jobs in Durham, NC? The most popular types of Python Developer jobs in Durham, NC are:
What are popular job titles related to Senior Python Developer jobs in Durham, NC? For Senior Python Developer jobs in Durham, NC, the most frequently searched job titles are:
What job categories do people searching Senior Python Developer jobs in Durham, NC look for? The top searched job categories for Senior Python Developer jobs in Durham, NC are:
What cities near Durham, NC are hiring for Senior Python Developer jobs? Cities near Durham, NC with the most Senior Python Developer job openings:
Senior Python Developer jobs near you
Infographic showing various Senior Python Developer job openings in Durham, NC as of August 2026, with employment types broken down into 2% Internship, 84% Full Time, 8% Part Time, and 6% Contract. Highlights an 79% Physical, 6% Hybrid, and 15% Remote job distribution, with an average salary of $128,639 per year, or $61.8 per hour.

Senior Python Developer

Compunnel

Durham, NC • On-site

$117K - $158K/yr

Contractor

Re-posted 13 days ago

Job description

Job Summary
The Senior Python Developer is responsible for designing, developing, and maintaining mission-critical enterprise applications with a strong focus on backend development, API integrations, and system modernization. This role supports a core monolithic platform built with Python and Django while driving architectural improvements, mentoring engineers, and delivering scalable, high-quality software solutions. The ideal candidate has extensive experience with Python, Django, TypeScript, API development, and full-stack application engineering.
Key Responsibilities
• Design, develop, and maintain enterprise applications using Python and Django.
• Enhance and support a core monolithic application responsible for processing and orchestration.
• Design, develop, and maintain RESTful APIs and integration services for internal systems.
• Build and enhance full-stack applications with a strong emphasis on backend development and TypeScript.
• Develop and maintain integrations supporting enterprise platform functionality.
• Perform system modernization, performance improvements, and platform stability enhancements.
• Participate in architecture discussions and contribute to technical design decisions.
• Troubleshoot production issues, perform root cause analysis, and implement permanent solutions.
• Participate in production support and on-call rotations.
• Collaborate with cross-functional teams including product, platform, and business stakeholders.
• Mentor junior engineers and promote software engineering best practices.
• Communicate technical concepts effectively with both technical and non-technical stakeholders.
• Contribute to continuous improvement initiatives and engineering standards.
Required Qualifications
• 7+ years of professional software engineering experience.
• Strong hands-on experience with Python development.
• Strong experience developing enterprise applications using Django.
• Full-stack development experience with a strong backend focus.
• Extensive experience developing RESTful APIs and service-oriented architectures.
• Strong experience with TypeScript for frontend and backend development.
• Experience working with MySQL databases.
• Strong knowledge of software architecture, system design, and application development best practices.
• Strong analytical, debugging, troubleshooting, and problem-solving skills.
• Excellent communication, collaboration, and mentoring skills.
• Ability to independently solve complex technical problems and deliver scalable solutions.
Preferred Qualifications
• Experience in healthcare technology, clinical laboratory, or genomics environments.
• Experience with AWS cloud services and cloud-native application development.
• Experience with Docker, Kubernetes, or containerized application deployments.
• Experience with Infrastructure as Code tools such as Terraform.
• Experience designing and maintaining enterprise API platforms.
• Familiarity with AI-assisted development tools such as Claude or Codex.
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About Compunnel

Sourced by ZipRecruiter

Compunnel is a well-known company located in Plainsboro, NJ, US, recognized in the industry of IT Services and Solutions. Established in 1989, Compunnel offers a suite of services that help businesses integrate technology efficiently into their operations, a recognizable name in the IT solutions sphere for over three decades. The company’s service portfolio includes Digital Transformation, Business Intelligence, Cloud Services, Cybersecurity, and Application Modern Services, among others. Guided by its mission "to innovate with industry-leading digital solutions and disruptive tech strategies for unimagining business growth," the company underlines its commitment to offering out-of-the-box solutions to its clients. Remarkable achievements of the company include serving more than 30 Fortune 500 companies and providing job opportunities for over 50,000 individuals.

Industry

It services

Company size

501 - 1,000 Employees

Headquarters location

Plainsboro, NJ, US

Year founded

1994

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