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Senior Python Developer Jobs in Charlotte, NC (NOW HIRING)

1 point system

Sr Python Developer

Fort Mill, SC · Remote

$124K - $167K/yr

Job Title Sr Python Developer Location 100% Remote Work Duration 6 months + (Contract) MUST HAVE: * 7+ years of experience, senior level * Experience in Design and Development * Full Stack with ...

Accord Technologies Inc.

Python developer

Charlotte, NC · On-site

$49 - $67.75/hr

Sr Python developer Work Location : Charlotte NC Face to Face interview needed in charlotte NC 12 months Position type; W2 contract. About the Role: We are seeking a talented Python Developer to join ...

Sarian, Inc.

Sr. Python Web Developer

Charlotte, NC · On-site

$118K - $159K/yr

Role: Sr. Python Web Developer/Only USC & GC Location: Charlotte, NC Onsite position Fulltime position *****NO C2C***** JD Skill: Sr. Python Web Developer * 9 - 14 Years of experience as Sr.Python ...

Sarian, Inc.

Sr. Python Web Developer

Charlotte, NC · On-site

$118K - $159K/yr

Role: Sr. Python Web Developer Location: Charlotte, NC Onsite position Fulltime position JD Skill: Sr. Python Web Developer * 9 - 14 Years of experience as Sr.Python Web Developer * Expert in Python ...

Sarian, Inc.

Sr. Python Web Developer

Charlotte, NC · On-site

$118K - $159K/yr

Role: Sr. Python Web Developer Location: Charlotte, NC Onsite position Fulltime position *****NO C2C***** JD Skill: Sr. Python Web Developer Must Have Technical/Functional Skills: * Expert in Python ...

Staffingine LLC

Sr .Net Python Developer

Charlotte, NC · On-site

$118K - $159K/yr

Job Title: Sr .Net Python Developer Job Location: Charlotte, NC Job Type: Contract * Candidate should have 10+ years of experience in below technologies. * Microsoft Technologies C# ASPNET Core ...

Lorven Technologies

Python Developer AI/ML

Charlotte, NC · On-site

$49 - $67.75/hr

Python Developer - AI/ML Location: Charlotte, NC or Irving, TX Contract Interview Process: Final ... In this role, you will work closely with Senior Engineers, leads, and product teams to design ...

1 point system

Python DevOps Engineer

Charlotte, NC · On-site

Client is seeking a mid-level to senior engineer to join client's team on a contract basis to help ... Core Skills: * Strong Python development skills for enterprise-scale automation and service ...

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Showing results 1-20

All JobsPython Developer JobsSenior Python Developer JobsSenior Python Developer Jobs in Charlotte, NC

Senior Python Developer information

See Charlotte, NC salary details

$53.7K

$138.7K

$190.5K

How much do senior python developer jobs pay per year?

As of Jul 28, 2026, the average yearly pay for senior python developer in Charlotte, NC is $138,670.00, according to ZipRecruiter salary data. Most workers in this role earn between $118,700.00 and $159,700.00 per year, depending on experience, location, and employer.

What are the main responsibilities of a Senior Python Developer?

A Senior Python Developer is responsible for designing, developing, and maintaining complex software applications using the Python programming language. They lead the technical aspects of projects, mentor junior developers, and ensure code quality through code reviews and best practices. Additionally, they collaborate with cross-functional teams to gather requirements, solve technical challenges, and deploy scalable and efficient solutions. Senior Python Developers are also expected to stay updated with the latest trends and advancements in Python and related technologies.

What is the difference between Senior Python Developer vs Python Developer?

AspectSenior Python DeveloperPython Developer
Required ExperienceTypically 5+ years, with leadership and complex project experienceUsually 1-3 years, focusing on core Python skills
ResponsibilitiesDesigning architecture, mentoring, handling complex systemsWriting code, debugging, implementing features
CertificationsOptional but beneficial (e.g., Python certifications, cloud certs)Often not required
Work EnvironmentCollaborative teams, project planning, code reviewsDevelopment-focused, task-oriented

The main difference between a Senior Python Developer and a Python Developer lies in experience, responsibilities, and leadership. Senior developers handle complex projects, mentor others, and often participate in architecture decisions, while Python Developers focus on coding and feature implementation. Both roles are essential in tech companies, but the senior role requires more experience and broader skills.

What are the key skills and qualifications needed to thrive as a Senior Python Developer, and why are they important?

To thrive as a Senior Python Developer, you need advanced proficiency in Python programming, experience with software architecture, and a solid understanding of algorithms and data structures, usually backed by a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and containerization tools like Docker are typically required, alongside knowledge of modern CI/CD pipelines. Strong problem-solving abilities, effective communication, and leadership skills help you collaborate with teams and mentor junior developers. Mastery of these skills ensures the delivery of scalable, maintainable software solutions and the ability to drive technical excellence within development teams.

What are some common challenges faced by Senior Python Developers when leading a development team?

Senior Python Developers often encounter challenges such as balancing hands-on coding with mentoring junior team members and ensuring code quality across the team. They are also responsible for making architectural decisions, which requires staying updated on best practices and emerging Python frameworks. Additionally, coordinating collaboration between cross-functional teams (like DevOps, QA, and front-end developers) can be complex, especially in agile environments where requirements may shift rapidly. Overcoming these challenges helps foster a productive and innovative team culture.
What are the most commonly searched types of Python Developer jobs in Charlotte, NC? The most popular types of Python Developer jobs in Charlotte, NC are:
What are popular job titles related to Senior Python Developer jobs in Charlotte, NC? For Senior Python Developer jobs in Charlotte, NC, the most frequently searched job titles are:
What job categories do people searching Senior Python Developer jobs in Charlotte, NC look for? The top searched job categories for Senior Python Developer jobs in Charlotte, NC are:
What cities near Charlotte, NC are hiring for Senior Python Developer jobs? Cities near Charlotte, NC with the most Senior Python Developer job openings:
Senior Python Developer jobs near you
Infographic showing various Senior Python Developer job openings in Charlotte, NC as of July 2026, with employment types broken down into 82% Full Time, 5% Part Time, 1% Temporary, and 12% Contract. Highlights an 82% Physical, 5% Hybrid, and 13% Remote job distribution, with an average salary of $138,670 per year, or $66.7 per hour.
Sr Python Developer

Sr Python Developer

1 point system

Fort Mill, SC • Remote

$124K - $167K/yr

Contractor

Posted 5 days ago

Job description

Hi ,
I hope you're doing well.

I'm reaching out regarding an exciting opportunity that I believe aligns well with your background and skill set.

To move forward, could you please provide the following details along with latest copy of resume:

two references are required in order to submit for this role. Without those I won’t be able to submit you.

Work Authorization and Expiry (If any)

LinkedIn Profile URL

Current Location with Zip code

Pay Expectation on W2 (hourly)

Complete JD:

Job Title

Sr Python Developer

Location

100% Remote Work

Duration

6 months + (Contract)

MUST HAVE:

  • 7+ years of experience, senior level
  • Experience in Design and Development
  • Full Stack with Python, Django, and Typescript
  • Typescript
  • Heavy APIs on backend
  • MySQL

Nice-to-Have / Preferred:

  • AI Tools – Claude, Codex, etc

Job Description:

Role Overview

We are seeking a Senior Software Engineer to support a core monolithic system that orchestrates lab order intake, processing, and interpretation. This role requires an individual who can take ambiguous, complex problems and drive them to completion. The successful candidate will act as a technical leader, mentoring other engineers and raising the bar for the team in architecture and execution, with a heavy focus on integration work connecting internal systems with lab pipelines.

Key Responsibilities

  • Own and deliver projects across product, platform, and stakeholder teams.
  • Design, develop, and maintain a central, monolithic system built on Python and Django.
  • Develop and enhance system integrations and core platform functionality with a strong emphasis on API-driven architecture.
  • Perform foundational engineering work focused on system improvements, stability, and modernization.
  • Provide production support, including participating in an on-call rotation and troubleshooting bugs.
  • Mentor teammates and elevate the team's technical execution standards.
  • Communicate clearly with both technical and non-technical audiences.

Required Qualifications

Experience: A minimum of 7+ years of professional software engineering experience is required. Candidates must demonstrate strong experience in system design, development, and real-world application architecture.

Technical Skills: Proficiency in Python and Django is mandatory. Candidates must have full-stack experience with a strong backend emphasis, including heavy API development and experience with TypeScript and MySQL.

Education: A formal degree is not required. Experience and technical skill are prioritized.

Preferred Qualifications

  • Experience in healthcare technology, clinical laboratory, or genomics industries.
  • Knowledge of AWS-native environments and cloud platforms.
  • Familiarity with containerization, Kubernetes, or infrastructure-as-code tools like Terraform.
  • Experience designing and maintaining API platforms that serve multiple internal consumers.
  • Familiarity with AI development tools such as Claude or Codex.

Thank You

Ranjeet Kumar | 1Point System LLC

Senior Technical Recruiter
• Email: ranjeet@1pointsys.com • Fax: 803-832-7973 • www.1pointsys.com

https://www.linkedin.com/in/ranjeet-kumar-829a4525b/

If you are unable to reach me directly, please feel free to contact my supervisor at ashish.trivedi@1pointsys.com . They will be able to assist you with any inquiries or provide the support you need.


115 Stone Village Drive • Suite C • Fort Mill, SC • 29708

         An E-Verified company | An Equal Opportunity Employer