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Senior Medical Director Jobs (NOW HIRING)

Lyric

Senior Medical Director

$216K - $324K/yr

The Senior Medical Director is a senior clinical leader who will represent Lyric in strategic engagements with payer clients. This individual will proactively map, establish, and strengthen ...

Umoja Biopharma

Senior Medical Director

Seattle, WA · On-site

$270K - $333K/yr

Senior Director Level: MD, MD/PhD, or equivalent medical degree. Board certification in Oncology, Hematology, or related specialty strongly preferred. Minimum of 5 years of clinical development ...

Jobtailor

NY · On-site

$230 - $350/hr

Serve as senior clinical advisor to executive leadership on utilization trends * Oversee the ... Conduct and support training of medical directors and UM staff Requirements * Doctor of Medicine ...

Premier Research

Senior Medical Director

$200K/yr

Premier Research is looking for a Senior Medical Director to join our Medical Affairs team. You will help biotech, medtech, and specialty pharma companies transform life-changing ideas and ...

WellSense Health Plan

Medical Director

MA · On-site +1

$173K - $250K/yr

The Medical Director will report to the Senior Medical Director of Utilization Management, Member Appeals & Grievances, and Medical Policy (Senior Medical Director of Utilization Management) and ...

BMC HealthNet Plan

Medical Director

Boston, MA · On-site +1

$173K - $250K/yr

The Medical Director will report to the Senior Medical Director of Utilization Management, Member Appeals & Grievances, and Medical Policy (Senior Medical Director of Utilization Management) and ...

Therakos

Senior Medical Director, Immunology

Malvern, PA

$215K - $280K/yr

Job Title Senior Medical Director, Immunology Requisition JR000015598 Senior Medical Director, Immunology (Open) Location Bridgewater, NJ Additional Locations Malvern, PA, Philadelphia, PA Summary ...

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Senior Medical Director information

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$39.5K

$142.9K

$279.5K

How much do senior medical director jobs pay per year?

As of Aug 8, 2026, the average yearly pay for senior medical director in the United States is $142,920.00, according to ZipRecruiter salary data. Most workers in this role earn between $101,500.00 and $161,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a senior medical director, and why are they important?

To thrive as a Senior Medical Director, you need extensive clinical expertise, leadership experience, and an advanced medical degree such as an MD or DO. Familiarity with regulatory compliance systems, clinical trial management software, and certifications like board certification in a relevant specialty are typically required. Strategic vision, strong decision-making, and excellent communication skills help you lead multidisciplinary teams and drive organizational objectives. These skills and qualifications are crucial for ensuring high standards of patient care, regulatory adherence, and the effective leadership of medical initiatives.

What is the difference between Senior Medical Director vs Medical Director?

AspectSenior Medical DirectorMedical Director
CredentialsMD or DO, board certification, extensive experienceMD or DO, board certification, relevant experience
Work EnvironmentStrategic leadership, overseeing multiple projects or regionsOperational management, overseeing clinical teams or departments
Employer & IndustryPharmaceuticals, biotech, healthcare organizationsHospitals, clinics, healthcare systems
Search & Comparison IntentUnderstanding senior leadership roles in medical managementClarifying clinical leadership responsibilities

The main difference between a Senior Medical Director and a Medical Director lies in their level of seniority and scope. Senior Medical Directors typically hold higher strategic responsibilities, oversee larger teams or regions, and have more extensive experience. Medical Directors focus more on operational and clinical management within specific departments. Both roles require medical credentials and industry experience, but the Senior Medical Director's role emphasizes leadership at a broader organizational level.

How does a senior medical director typically collaborate with cross-functional teams within a healthcare organization?

A Senior Medical Director frequently works alongside professionals from clinical operations, regulatory affairs, research, and commercial teams to ensure that medical strategies align with both patient care standards and organizational objectives. This collaboration often involves leading meetings, providing medical expertise on project decisions, and coordinating efforts across departments to support clinical trials or product development. By fostering open communication and aligning priorities, the Senior Medical Director plays a key role in driving successful outcomes while maintaining compliance with industry regulations.
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Senior Medical Director jobs near you
Infographic showing various Senior Medical Director job openings in the United States as of August 2026, with employment types broken down into 1% As Needed, 78% Full Time, 15% Part Time, and 6% Contract. Highlights an 91% Physical, 1% Hybrid, and 8% Remote job distribution, with an average salary of $142,920 per year, or $68.7 per hour.

Senior Medical Director

Sagimet Biosciences

Foster City, CA • On-site

Full-time

Posted 20 days ago

Job description

Job Type
Full-time
Description
As a Senior Medical Director, you will play a critical role in planning and executing Sagimet's clinical trial programs. You will collaborate closely with cross-functional team members, including representatives from Clinical Operations, Regulatory Affairs, Safety Pharmacovigilance, Translational Sciences and Biomarkers, Biometrics, Medical Writing, Research & Development, and Program Management. Your expertise will drive successful planning, execution, analysis and reporting of clinical trials and contribute to the advancement of novel therapies.
Essential Responsibilities:
Clinical Development:
  • Design, analysis, interpretation, and reporting of clinical trials
  • Medical leadership for the development of clinical study protocols, Investigator Brochures, Clinical Study Reports, regulatory submissions, and other study-related documents
  • Monitor ongoing clinical trials, ensuring adherence to protocols, safety guidelines, and regulatory requirements
  • Review safety events, adverse reactions, and serious adverse events (SAEs)

Collaboration and Leadership:
  • Work closely with the Clinical Operations team to support trial execution
  • Key medical contact for study investigators, DSMBs, IRBs
  • Provide scientific and strategic leadership, contributing to trial design, endpoints, and patient selection
  • Collaborate with cross-functional team members to develop scientifically sound clinical trial protocols, statistical analysis plans and other study documents that are feasible to execute. Contribute to interactions with regulatory authorities and regulatory submissions
  • Collaborate with study investigators in the preparation, submission, and presentation of scientific data at scientific meets and congresses
  • Maintain current knowledge of therapeutic areas and industry advancements through conferences, literature, and training
  • Represent the company at scientific conferences and engage with key opinion leaders

Requirements
Education and Experience:
  • Medical degree (MD) with board certification, dermatology experience would be a plus
  • 5+ years of experience in clinical development within the biotechnology or pharmaceutical industry with expertise in clinical trial design, execution, and data analysis
  • Expertise in dermatology studies would be a plus
  • Experience in regulatory interactions, submissions, and/or NDA/BLA filings
  • Experience in scientific communication of clinical results through presentations to internal and external audiences, abstracts and publications
  • Excellent verbal and written communication skills, ability to collaborate effectively with thought leaders and investigators
  • Ability to provide scientific and strategic leadership
  • Strong decision-making skills
  • Ability to work in a fast-paced, small company environment with multiple competing responsibilities
  • Position involves 10-20% travel

Apply