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Senior Clinical Research Jobs (NOW HIRING)

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Senior Clinical Research Associate

San Diego, CA · Hybrid

$110K - $138K/yr

Senior Clinical Research Associate - Oncology - Southern California ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and ...

ICON

Senior Clinical Research Associate

Miami, FL · On-site +1

Senior Clinical Research Associate - Oncology Phase I - Miami, FL ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments ...

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Senior Clinical Research Associate

Miami, FL · Hybrid

Senior Clinical Research Associate - Oncology Phase I - Miami, FL ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments ...

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Senior Clinical Research information

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$36K

$94.3K

$143.5K

How much do senior clinical research jobs pay per year?

As of Aug 10, 2026, the average yearly pay for senior clinical research in the United States is $94,314.00, according to ZipRecruiter salary data. Most workers in this role earn between $62,500.00 and $128,000.00 per year, depending on experience, location, and employer.

What are the typical challenges faced by senior clinical research professionals when overseeing multiple clinical trials?

Senior Clinical Research professionals often juggle multiple studies simultaneously, which can present challenges such as managing tight timelines, ensuring compliance with regulatory requirements, and coordinating cross-functional teams. Balancing these responsibilities requires strong organizational and communication skills, as well as the ability to adapt quickly to shifting project priorities. Effective collaboration with investigators, sponsors, and regulatory bodies is key to overcoming obstacles and ensuring the success of each trial.

What are the key skills and qualifications needed to thrive as a senior clinical research professional?

To thrive as a Senior Clinical Research professional, you need a strong background in clinical trial design, regulatory compliance, data analysis, and typically a degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and certifications such as Good Clinical Practice (GCP) are often required. Excellent leadership, problem-solving, and communication skills help drive project success and effective cross-functional collaboration. These skills and qualities are essential for ensuring the integrity, efficiency, and regulatory adherence of clinical research projects.

What is a senior clinical research professional?

A Senior Clinical Research professional is an experienced individual who oversees and manages clinical trials and research projects, often within the healthcare or pharmaceutical industries. They are responsible for ensuring studies comply with regulatory guidelines, managing study teams, designing protocols, analyzing data, and ensuring the safety and integrity of clinical trials. Typically, they serve as a liaison between sponsors, regulatory authorities, and research teams, and may also be involved in mentoring junior staff. This role requires a strong background in clinical research, regulatory knowledge, and leadership skills.

What is the difference between Senior Clinical Research vs Clinical Research Coordinator?

AspectSenior Clinical ResearchClinical Research Coordinator
Required CredentialsBachelor's degree, often advanced degrees, and experienceBachelor's degree, certification preferred
Work EnvironmentLeads projects, manages teams, oversees study progressSupports study activities, coordinates participant recruitment and data collection
Employer & Industry UsagePharmaceutical companies, CROs, academic institutionsResearch sites, hospitals, clinics
Common Search & ComparisonHigher-level responsibilities, project managementEntry to mid-level, operational focus

In summary, Senior Clinical Research professionals typically oversee entire studies, manage teams, and handle complex project aspects, requiring more experience and credentials. Clinical Research Coordinators focus on day-to-day study operations, participant management, and data collection, often serving as the operational backbone of clinical trials.

More about Senior Clinical Research jobs
What cities are hiring for Senior Clinical Research jobs? Cities with the most Senior Clinical Research job openings:
What are the most commonly searched types of Clinical Research jobs? The most popular types of Clinical Research jobs are:
What states have the most Senior Clinical Research jobs? States with the most job openings for Senior Clinical Research jobs include:
What job categories do people searching Senior Clinical Research jobs look for? The top searched job categories for Senior Clinical Research jobs are:
Senior Clinical Research jobs near you
Infographic showing various Senior Clinical Research job openings in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $94,314 per year, or $45.3 per hour.

Senior Clinical Research Associate

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Los Angeles, CA • Hybrid

$110K - $138K/yr

Full-time

Medical, Dental, Vision, Life, Retirement

Re-posted 15 days ago

Job description

Senior Clinical Research Associate - Oncology - Los Angeles, CA

ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.


As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.


The Sr. Clinical Research Associate (Sr. CRA) willbe responsible forperforming investigative site management and monitoring activities throughout the clinical trial lifecycle. This Sr. CRA role will support the client's Oncology clinical trials to ensure data integrity, subject safety, andinspectionreadiness at the clinical investigative sites.

Responsibilities:

  • Perform site management activities to support the client's Oncology site success andmaintaina continuous state of inspection readiness

  • Act as the primary contact andfacilitateefficient communications between the the client's clinical trial team and the sites

  • Perform remote and on-site monitoring/co-monitoring visits (Site Qualification Visits, Site Initiation Visits, Interim Monitoring Visits and Close-Out Visits) to ensure data integrity and subject safety in the client's trials

  • May perform oversight activities to assess monitoring quality and train/mentor less experienced CRAs

  • Promptly document monitoring activities andsubmit/approve visit reports

  • Manage site essential document collection and TMF reconciliation with site files

  • Support sites with local Institutional Review Board (IRB)/Ethics Committee (EC) submissions and confirm approvals

  • Regularly review site Key Risk Indicator (KRI) metrics,issuesand action items to detect trends and ensure prompt resolution

  • Independentlydetermineroot causes and develop/implement site Corrective Action and Preventive Action (CAPA) plans

  • Deliver training to ensure sitescomply withthe protocol, Standard Operating Procedures (SOPs), Good Clinical Practices (GCPs)and regulations

  • Support sites and the client's regulatory inspections

  • Contribute to site identification; drive site feasibility and qualification progress; and support site activation activities

  • Lead site engagement initiatives and foster relationships with key Oncology sites and networks

Qualifications

  • Bachelor's degree (scientific field preferred)

  • 5+ yearsmonitoringclinical trials independently conducting on-site and remote monitoring visits. Atleast 2 years monitoring solid tumor clinical trials.

  • 1+ years early development trial experience

  • Solidtumorclinical trial experience is required

  • Experience utilizing Veeva systems is highly preferred

  • Demonstrated experience developing/maintainingsite relationships and securing compliance

  • ExpertiseinGxPsand Oncology monitoring techniques (including Risk-Based Monitoring) and terminology

  • Experience collaborating with sites frominitialengagement through close-out phases

  • Experience activating sites

  • Experience training site staff

  • Experience supporting sites and/or sponsors in regulatory inspections

  • Experience working within a Functional Services (or in-house) monitoring model is preferred

  • Willing to travel up to 50%


Employment with ICON is contingent upon having the legal right to work in the country where the role is based.


Rewards & Benefits

ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.


Benefits may include:

  • Competitive base salary and performance related incentives
  • Health and wellbeing programmes including medical, dental, and vision coverage where applicable
  • Retirement and pension plans
  • Life assurance and disability coverage
  • Employee assistance programmes and wellbeing resources
  • Learning and development opportunities through structured training and career pathways

Benefits may vary depending on role and location.


Visit our careers site to read more about the benefits ICON offers.


Inclusion and Accessibility

ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.


If you require reasonable accommodations during the recruitment process, please let us know or submit a requesthere.

Salary Range

$110,520.00-$138,150.00

Are you a current ICON Employee? Please click here to apply

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