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Senior Clinical Research Jobs (NOW HIRING)

We are seeking an experienced Sr Clinical Research Coordinator (Sr. CRC) - ONCOLOGY to join a growing clinical research team supporting a diverse portfolio of investigator-initiated and industry ...

We are seeking an experienced Senior Clinical Research Coordinator (Sr. CRC) - ONCOLOGY to join a growing clinical research team supporting a diverse portfolio of investigator-initiated and industry ...

Senior Clinical Research Associate

Washington, DC · On-site +1

$110K - $138K/yr

Senior Clinical Research Associate - Oncology - Washington DC ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to ...

Senior Clinical Research Associate

Chicago, IL · On-site +1

$110K - $138K/yr

Senior Clinical Research Associate - Oncology Phase I - Chicago ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments ...

Senior Clinical Research Associate - Oncology Phase I - Chicago ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments ...

Showing results 21-40

Senior Clinical Research information

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$36K

$94.3K

$143.5K

How much do senior clinical research jobs pay per year?

As of Aug 7, 2026, the average yearly pay for senior clinical research in the United States is $94,314.00, according to ZipRecruiter salary data. Most workers in this role earn between $62,500.00 and $128,000.00 per year, depending on experience, location, and employer.

What are the typical challenges faced by senior clinical research professionals when overseeing multiple clinical trials?

Senior Clinical Research professionals often juggle multiple studies simultaneously, which can present challenges such as managing tight timelines, ensuring compliance with regulatory requirements, and coordinating cross-functional teams. Balancing these responsibilities requires strong organizational and communication skills, as well as the ability to adapt quickly to shifting project priorities. Effective collaboration with investigators, sponsors, and regulatory bodies is key to overcoming obstacles and ensuring the success of each trial.

What are the key skills and qualifications needed to thrive as a senior clinical research professional?

To thrive as a Senior Clinical Research professional, you need a strong background in clinical trial design, regulatory compliance, data analysis, and typically a degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and certifications such as Good Clinical Practice (GCP) are often required. Excellent leadership, problem-solving, and communication skills help drive project success and effective cross-functional collaboration. These skills and qualities are essential for ensuring the integrity, efficiency, and regulatory adherence of clinical research projects.

What is a senior clinical research professional?

A Senior Clinical Research professional is an experienced individual who oversees and manages clinical trials and research projects, often within the healthcare or pharmaceutical industries. They are responsible for ensuring studies comply with regulatory guidelines, managing study teams, designing protocols, analyzing data, and ensuring the safety and integrity of clinical trials. Typically, they serve as a liaison between sponsors, regulatory authorities, and research teams, and may also be involved in mentoring junior staff. This role requires a strong background in clinical research, regulatory knowledge, and leadership skills.

What is the difference between Senior Clinical Research vs Clinical Research Coordinator?

AspectSenior Clinical ResearchClinical Research Coordinator
Required CredentialsBachelor's degree, often advanced degrees, and experienceBachelor's degree, certification preferred
Work EnvironmentLeads projects, manages teams, oversees study progressSupports study activities, coordinates participant recruitment and data collection
Employer & Industry UsagePharmaceutical companies, CROs, academic institutionsResearch sites, hospitals, clinics
Common Search & ComparisonHigher-level responsibilities, project managementEntry to mid-level, operational focus

In summary, Senior Clinical Research professionals typically oversee entire studies, manage teams, and handle complex project aspects, requiring more experience and credentials. Clinical Research Coordinators focus on day-to-day study operations, participant management, and data collection, often serving as the operational backbone of clinical trials.

More about Senior Clinical Research jobs
What cities are hiring for Senior Clinical Research jobs? Cities with the most Senior Clinical Research job openings:
What are the most commonly searched types of Clinical Research jobs? The most popular types of Clinical Research jobs are:
What states have the most Senior Clinical Research jobs? States with the most job openings for Senior Clinical Research jobs include:
Infographic showing various Senior Clinical Research job openings in the United States as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $94,314 per year, or $45.3 per hour.

Full-time

Re-posted 20 hours ago


Job description

The Senior Clinical Research Associate is responsible for overseeing the execution of clinical trials at Investigative Sites. The Clinical Research Associate acts as a liaison between the study Sponsor, CRC and Investigative Sites. They will proactively identify and resolve clinical project issues and participate in process improvement initiatives as applicable. The CRA facilitates successful execution of studies by Investigative Sites and helps to ensure the rights, safety and welfare of human research participants as well as data integrity in clinical trials.
Essential Duties & Responsibilities
  • Initiates, monitors, and closes-out investigative sites in accordance with FDA/ICH regulations.
  • Tracks and maintains study specific non-Case Report Form database
  • Administers Clinical research projects; collects investigator documentation, site management, clinical contact, and prepare reports as required
  • Ensures appropriate source document review and source document verification as required
  • Reviews Case Report Forms to identify erroneous, missing, or incomplete data
  • Generates queries to resolve problematic data to appropriate personnel, and review responses to assure the database is updated accordingly
  • Verifies study drug accountability; generates and tracks drug shipments and storage
  • Travels as necessary, based on project needs and according to Clinical Monitoring Plan requirements
  • Performs data collection, retrieval, entry and clean up as necessary
  • Develops and maintains strong relationships with Investigator(s) and site staff
  • Independently manages sites resulting in acceptable Quality Assurance reports.
  • Escalates study/site issues/deviations appropriately
  • Serves as lead monitor for a protocol or project by creating study files, arranges monitoring schedules, leads the project team, organize and run meetings and performs other project management duties as assigned by management
  • Writes Clinical Trial Reports, analyzing and presenting trial results in a clear and accurate format
  • Reports, writes narratives, and follows-up on reported serious adverse events
  • Interacts and attends client meetings, as appropriate
  • Mentors junior staff/CRAs
  • Quality oversight checks of monitoring
  • Performs other duties as assigned

Qualifications
  • Bachelor's degree, or RN, in a related field or equivalent combination of education, training and experience
  • Minimum 5 years' experience as a CRA; experience overseeing clinical trials in the pharmaceutical, hospital or CRO industry
  • Ability to work and travel independently with minimal supervision
  • Experience with numerous EDC systems.
  • Advanced knowledge of GCPs, ICH guidelines, FDA and other applicable regulations
  • Specialized knowledge of CNS therapeutic areas
  • Proficiency in Microsoft Office, Zoom and Adobe
  • Excellent writing and verbal skills, English language proficiency
  • Meticulous attention to detail
  • Time management and ability to prioritize tasks
  • Ability to travel up to 70%

Department Clinical Operations Role Senior Clinical Research Associate Locations Remote, US Remote status Fully Remote Employment type Full-time