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Rare Disease Jobs (NOW HIRING)

Head of Sales, Rare Disease

Madison, NJ · On-site

$250K - $350K/yr

As Head of Sales, Rare Disease, you will lead the US rare disease sales organization and deliver excellent field execution across the rare disease portfolio: maximizing performance of Spevigo for GPP ...

Head of Sales, Rare Disease

Madison, NJ · On-site

$250K - $350K/yr

As Head of Sales, Rare Disease, you will lead the US rare disease sales organization and deliver excellent field execution across the rare disease portfolio: maximizing performance of Spevigo for GPP ...

As a Rare Disease Sales Consultant - Spevigo, you will execute LEO Pharma's dermatology sales and marketing strategies to ensure strong distribution and market penetration of our specialty products.

Summary of Job (brief description) The Rare Disease Specialist role at Soleno will drive year two commercialization of DCCR and sales initiatives of Soleno's leading product candidate, DCCR, for the ...

Summary of Job (brief description) The Rare Disease Specialist role at Soleno will drive year two commercialization of DCCR and sales initiatives of Soleno's leading product candidate, DCCR, for the ...

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Rare Disease information

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$38.5K

$121.7K

$338.5K

How much do rare disease jobs pay per year?

As of Sep 2, 2026, the average yearly pay for rare disease in the United States is $121,720.00, according to ZipRecruiter salary data. Most workers in this role earn between $54,000.00 and $250,000.00 per year, depending on experience, location, and employer.

What is a rare disease?

A Rare Disease job involves working in roles focused on researching, developing treatments, and advocating for conditions that affect a small percentage of the population. These roles exist in pharmaceutical companies, biotech firms, healthcare organizations, and non-profits, spanning areas like drug development, regulatory affairs, patient advocacy, and medical affairs. Professionals in this field collaborate with researchers, clinicians, and policymakers to address unmet medical needs and improve patient outcomes.

What are common challenges faced by professionals working in the rare disease field?

Professionals working in the Rare Disease field often encounter challenges related to limited clinical data, small patient populations, and complex regulatory pathways. Collaborating closely with patient advocacy groups, regulatory bodies, and multidisciplinary teams is essential to overcome these obstacles. You may also need to navigate evolving therapeutic landscapes and work with innovative trial designs. However, these challenges make the work highly impactful and offer opportunities to contribute meaningfully to unmet medical needs and to advance your career as an expert in a specialized area.

What are the key skills and qualifications needed to thrive in the rare disease position, and why are they important?

To excel in a Rare Disease role, professionals typically need a background in life sciences, clinical research, or healthcare, often supported by advanced degrees such as MD, PharmD, or PhD. Familiarity with regulatory requirements, clinical trial management systems, and rare disease registries is crucial. Excellent communication, problem-solving, and collaboration skills set top performers apart in multidisciplinary teams. These competencies are vital for driving progress in developing treatments and support initiatives for populations with unique medical needs.

More about Rare Disease jobs

What cities are hiring for Rare Disease jobs?

Cities with the most Rare Disease job openings:

What are the most commonly searched types of Rare Disease jobs?

The most popular types of Rare Disease jobs are:

What states have the most Rare Disease jobs?

States with the most job openings for Rare Disease jobs include:

Infographic showing various Rare Disease job openings in the United States as of August 2026, with employment types broken down into 3% As Needed, 77% Full Time, 17% Part Time, and 3% Contract. Highlights an 92% Physical, 1% Hybrid, and 7% Remote job distribution, with an average salary of $121,720 per year, or $58.5 per hour.

Head of Sales, Rare Disease

Leo Pharma

Madison, NJ • On-site

$250K - $350K/yr

Full-time

Posted 11 days ago


Job description

Application deadline:  
Location: Madison 07940, New Jersey, United States 
Contract type: Permanent 
Job ID: 4810 

Role Description

Lead the future of rare disease at LEO Pharma. 

Shape the strategy, performance, and evolution of our US rare disease business, driving results today while building the field organization and capabilities needed to support the next chapter of growth across the portfolio. 

Your Role:  

As Head of Sales, Rare Disease, you will lead the US rare disease sales organization and deliver excellent field execution across the rare disease portfolio: maximizing performance of Spevigo for GPP in the current indication while building field launch readiness for a new rare disease program in the pre-launch phase, with anticipated launch next year. The Head of Sales leads and develops 5 Regional Associate Directors and, through them, 33 Rare Disease Sales Consultants, and serves on the Rare Disease Leadership Team. The role translates brand strategy into field action in close partnership with marketing, market access, medical affairs, sales operations and training, and instills a high-performance, highly compliant, patient-centric culture suited to rare disease communities, where every interaction and every patient matters. 

Your Responsibilities: 

  • Lead, coach, and develop a high-performing team of Regional Associate Directors and Rare Disease Sales Consultants. 

  • Deliver sales performance across the rare disease portfolio, maximizing the success of Spevigo in GPP while preparing for the launch of a new rare disease program. 

  • Lead field launch readiness, including territory design, deployment, targeting, training, and execution planning. 

  • Drive sales force effectiveness through performance management, field KPIs, incentive compensation, analytics, and CRM utilization. 

  • Partner closely with Marketing, Market Access, Medical Affairs, and other cross-functional teams to translate strategy into exceptional field execution. 

  • Analyze market dynamics and field performance to inform strategy and optimize results. 

  • Build strong relationships with key opinion leaders, treating institutions, and professional communities. 

  • Champion a culture of compliance, accountability, and patient-centricity across the organization. 

  • Contribute to portfolio strategy, business planning, forecasting, and resource allocation as a member of the Rare Disease Leadership Team. 

Your Qualifications: 

  • Minimum of a bachelor's degree required; MBA or other advanced degree preferred. 

  • 12 plus years of progressive pharmaceutical/biotech commercial experience, including 8 plus years of sales leadership; previous second-line leadership (leading leaders) strongly preferred. 

  • Rare disease, orphan drug or specialty/biologics sales leadership experience strongly preferred; experience with buy-and-bill, specialty pharmacy or infused/injectable products a plus. 

  • Previous US product launch experience in a sales leadership role required; experience building field launch readiness for a rare disease or specialty launch strongly preferred. 

  • Proven track record of delivering sales results and leading organizations to a higher level of performance while ensuring compliance and high ethical standards. 

  • Strong understanding of sales incentive compensation structures, sales operations, field analytics and training. 

  • Strong understanding of US market access dynamics, including payer, specialty pharmacy, and site-of-care environments. 

  • Experience working cross-functionally in a highly matrixed organization. 

  • Willingness and ability to travel domestically as required, approximately 50% or more, including regular field visits. 

What Will Help You Succeed:

You are a strategic and patient-centric leader who knows how to inspire, develop, and elevate teams to achieve exceptional results. You bring strong business acumen, executive presence, and the ability to build trusted relationships across a diverse stakeholder group. Success in this role requires agility, accountability, and an entrepreneurial mindset, combined with a passion for developing talent and improving outcomes for patients living with rare diseases. 

Your New Team: 

You will report to the VP, Rare Disease and serve as a key member of the Rare Disease Leadership Team, leading a team of Regional Associate Directors and Rare Disease Sales Consultants across the US. You'll work closely with partners across Marketing, Market Access, Patient Services, Medical Affairs, Sales Operations, Analytics, Training, Compliance, and HR, while building relationships with key opinion leaders, treating institutions, centers of excellence, and patient advocacy organizations to help improve outcomes for patients living with rare diseases. 

Compensation: 

The base salary range for this position is $250,000-350,000 per year. The base salary range represents the anticipated low and high of the LEO Pharma range for this position. Salary will vary based on various factors such as the candidate's qualifications, skills, competencies, and proficiency for the role. In addition, some positions may include eligibility to earn commissions/bonus based on company and / or individual performance. 

Let's pioneer together! 

At LEO Pharma, we help people with skin diseases live fulfilling lives by advancing dermatology beyond the skin. We drive dermatology with our knowledge, collaboration, and curiosity, and we are at the forefront of science in developing new medicines. For us, pioneering together is about constantly improving and extending what's possible for each other, our company, and our patients.  

We welcome and consider applications from all qualified candidates because we believe that our different perspectives, backgrounds, and attitudes are what enable us to make the best decisions for LEO Pharma and meet the needs of the wonderfully diverse marketplace we operate in. 

For certain positions, LEO Pharma might complete a background check conducted by a third party.

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