ZipRecruiter

Log In

1

Medical Director Clinical Development Jobs (NOW HIRING)

GlaxoSmithKline

Director, Clinical Development

Waltham, MA · On-site

$86K - $117K/yr

Our approach to R&D GSK is seeking a Director, Clinical Development to provide clinical and ... Provide medical monitoring and oversight of the safety of study participants. * Act as clinical ...

Therakos

Senior Director, Clinical Development

Bridgewater, NJ · On-site

$81K - $111K/yr

Job Title Senior Director, Clinical Development Requisition JR000015604 Senior Director, Clinical ... Act as the primary medical monitor with support as required to identify any trial-related safety ...

next page

Showing results 1-20

All JobsMedical Director Clinical Development Jobs

Medical Director Clinical Development information

See salary details

$13K

$232.4K

$357K

How much do medical director clinical development jobs pay per year?

As of Jul 6, 2026, the average yearly pay for medical director clinical development in the United States is $232,369.00, according to ZipRecruiter salary data. Most workers in this role earn between $198,000.00 and $284,500.00 per year, depending on experience, location, and employer.

How does a Medical Director in Clinical Development typically collaborate with cross-functional teams during a clinical trial?

As a Medical Director in Clinical Development, you will regularly collaborate with cross-functional teams such as clinical operations, regulatory affairs, biostatistics, data management, and pharmacovigilance. Your role involves providing medical and scientific guidance, ensuring protocol adherence, and addressing safety or efficacy concerns throughout the trial. Effective communication and teamwork are essential for aligning on trial objectives, managing timelines, and resolving any emerging issues. This collaborative environment fosters a comprehensive approach to advancing clinical programs and supports the successful execution of clinical trials.

What does a Medical Director of Clinical Development do?

A Medical Director of Clinical Development is responsible for overseeing the planning, execution, and management of clinical trials for new drugs or medical products. They work closely with cross-functional teams, such as regulatory affairs, clinical operations, and research scientists, to ensure that clinical studies are designed effectively and conducted in compliance with regulatory standards. Their role also includes reviewing and interpreting clinical data, providing medical expertise, and contributing to the overall strategy for product development. Medical Directors play a crucial role in ensuring the safety and efficacy of new therapies before they reach the market.

What is the difference between Medical Director Clinical Development vs Medical Scientist?

AspectMedical Director Clinical DevelopmentMedical Scientist
Required CredentialsMD or DO, clinical research experience, industry certificationsMD, PhD, or equivalent, research-focused
Work EnvironmentPharmaceutical companies, biotech firms, clinical trial oversightResearch institutions, academia, laboratories
Employer & Industry UsageCommonly employed in industry to oversee clinical developmentPrimarily in research and academia, less in industry

The Medical Director Clinical Development typically oversees clinical trials and ensures regulatory compliance within the industry, requiring medical credentials and industry experience. Medical Scientists focus on research and discovery, often working in labs or academic settings. While both roles require advanced degrees, their work environments and primary responsibilities differ significantly.

What are the key skills and qualifications needed to thrive as a Medical Director Clinical Development, and why are they important?

To thrive as a Medical Director Clinical Development, you need an advanced medical degree (MD or equivalent), extensive clinical research experience, and a deep understanding of regulatory requirements and drug development processes. Familiarity with electronic data capture systems, clinical trial management software, and GCP/ICH guidelines is typically required. Strong leadership, strategic thinking, and exceptional communication skills help drive multidisciplinary teams and manage complex projects. These skills ensure the safe, efficient, and compliant progression of clinical programs from conception through regulatory approval.
More about Medical Director Clinical Development jobs
What cities are hiring for Medical Director Clinical Development jobs? Cities with the most Medical Director Clinical Development job openings:
What states have the most Medical Director Clinical Development jobs? States with the most job openings for Medical Director Clinical Development jobs include:
What job categories do people searching Medical Director Clinical Development jobs look for? The top searched job categories for Medical Director Clinical Development jobs are:
Medical Director Clinical Development jobs near you
Infographic showing various Medical Director Clinical Development job openings in the United States as of June 2026, with employment types broken down into 47% Full Time, 35% Part Time, and 18% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $232,369 per year, or $111.7 per hour.
Medical Director/Senior Medical Director, Clinical Development (Prostate)

Medical Director/Senior Medical Director, Clinical Development (Prostate)

ORIC Pharmaceuticals

San Diego, CA • On-site

$270K - $320K/yr

Full-time

Posted 4 days ago

Job description

Company Description
ORIC Pharmaceuticals is a clinical stage biopharmaceutical company dedicated to improving patients' lives by Overcoming Resistance In Cancer. ORIC's clinical stage product candidates include (1) rinzimetostat, an allosteric inhibitor of the polycomb repressive complex 2 (PRC2) via the EED subunit, being developed for prostate cancer, and (2) enozertinib, a brain penetrant inhibitor that selectively targets EGFR exon 20, HER2 exon 20 and EGFR atypical mutations, being developed across multiple genetically defined cancers. Beyond these two product candidates, ORIC® is also developing multiple precision medicines targeting other hallmark cancer resistance mechanisms. ORIC has offices in South San Francisco and San Diego, California. For more information, please go to www.oricpharma.com, and follow us on X or LinkedIn.
We are seeking an experienced oncology physician to serve as a Medical Director or Senior Medical Director at ORIC Pharmaceuticals. This role provides medical leadership across one or more clinical development programs, with a primary focus on late-stage (registration-enabling) clinical trials. The position plays a critical role in shaping clinical strategy, ensuring scientific rigor, guiding regulatory interactions, and advancing programs from study design through regulatory submission.
The Medical Director will work in close partnership with cross-functional teams including Clinical Operations, Regulatory Affairs, Biostatistics, Safety/Pharmacovigilance, Translational Medicine, and Medical Affairs. The role requires strong strategic thinking, hands-on execution, and the ability to lead effectively in a fast-paced biotech environment.
Job Description
Clinical and Medical Leadership
  • Serve as the medical lead for one or more oncology programs across all phases of development
  • Provide medical monitoring oversight for global clinical trials, including Phase 1-3 and registration-enabling studies.
  • Act as the primary medical expert for internal teams and external stakeholders
  • Represent the company in interactions with investigators, key opinion leaders, advisory boards, and regulatory authorities (e.g., FDA, EMA/CHMP)

Clinical Development Strategy and Execution
  • Partner with clinical scientists in the design and execution of clinical protocols, amendments, investigator brochures, study reports, abstracts, and manuscripts
  • Partner with biostatistics to define study endpoints, statistical plans, and data analyses
  • Ensure scientific rigor, data integrity, and patient-centric decision-making throughout development
  • Maintain strong clinical and scientific competitive intelligence through ongoing engagement with the oncology community and key scientific meetings

Cross-Functional Collaboration
  • Work closely with Clinical Operations and CROs to support trial execution and operational excellence
  • Collaborate with Regulatory Affairs on global regulatory strategy and submissions (e.g., INDs, NDAs, MAA)
  • Partner with Safety/Pharmacovigilance to review adverse events, monitor safety signals, and support benefit-risk assessments
  • Contribute to biomarker and translational strategies in collaboration with preclinical and translational teams

External Communication and Scientific Contribution
  • Support investigator engagement, site training, and advisory board activities
  • Contribute to abstracts, manuscripts, posters, and scientific presentations
  • Participate in scientific conferences and external meetings as a medical representative of the company

Leadership and Organizational Contribution
  • Lead and influence cross-functional teams in a matrixed environment
  • Contribute to the overall clinical development strategy and culture of scientific excellence to ensure alignment with ORIC's values, SOPs, and ethical standards

Qualifications
Education and Training
  • MD required
  • Board certified or board eligible in Oncology or Hematology/Oncology

Experience
  • 5+ years of experience in oncology clinical development, with increasing responsibility; experience in small-mid biotech environment is a plus
  • Demonstrated experience leading or contributing to late-phase oncology clinical trials; particularly in prostate cancer is desired
  • Strong understanding of global clinical development pathways and regulatory requirements (FDA, EMA, ICH/GCP)
  • Familiarity with current medical practice in GU oncology with development experience is a major plus
  • Prior experience as a principal investigator or academic clinician is a plus

Additional Information
The anticipated salary range for director level candidates who will work in our San Diego location is between $270,000-$320,000. The final salary offered to a successful candidate will be dependent on several factors that may include, but are not limited to, degree type (MD vs. non-MD), title, type and length of experience within the role, type and length of experience within the industry, education, geography, and other job-related factors.
ORIC Pharmaceuticals, Inc. is an equal opportunity employer. ORIC does not discriminate based on race, color, religion, gender, sexual orientation, gender identity, age, national origin, disability status, protected veteran status, or any other legally protected characteristics.

Apply