The Sr. Manager/Manager, Manufacturing will serve as a key operational leader at GeneFab, partnering closely with MSAT, Quality Assurance, Quality Control, Supply Chain, Facilities and Process ...
The Sr. Manager/Manager, Manufacturing will serve as a key operational leader at GeneFab, partnering closely with MSAT, Quality Assurance, Quality Control, Supply Chain, Facilities and Process ...
The Sr. Manager/Manager, Manufacturing will serve as a key operational leader at GeneFab, partnering closely with MSAT, Quality Assurance, Quality Control, Supply Chain, Facilities and Process ...
Quick apply
The Sr. Manager/Manager, Manufacturing will serve as a key operational leader at GeneFab, partnering closely with MSAT, Quality Assurance, Quality Control, Supply Chain, Facilities and Process ...
The Sr. Manager/Manager, Manufacturing will serve as a key operational leader at GeneFab, partnering closely with MSAT, Quality Assurance, Quality Control, Supply Chain, Facilities and Process ...
The Sr. Manager/Manager, Manufacturing will serve as a key operational leader at GeneFab, partnering closely with MSAT, Quality Assurance, Quality Control, Supply Chain, Facilities and Process ...
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We are seeking a dedicated and detail-oriented person to support data management activities for clinical trials. This role will contribute to database development, data quality oversight, and vendor ...
Quick apply
We are seeking a dedicated and detail-oriented person to support data management activities for clinical trials. This role will contribute to database development, data quality oversight, and vendor ...
We are seeking a dedicated and detail-oriented person to support data management activities for clinical trials. This role will contribute to database development, data quality oversight, and vendor ...
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Manager Manager information
See California salary details
$19.6K - $28.4K
7% of jobs
$28.4K - $37.2K
16% of jobs
$38.1K is the 25th percentile. Wages below this are outliers.
$37.2K - $46K
23% of jobs
The median wage is $47.7K / yr.
$46K - $54.8K
23% of jobs
$59.2K is the 75th percentile. Wages above this are outliers.
$54.8K - $63.6K
13% of jobs
$63.6K - $72.5K
7% of jobs
$72.5K - $81.3K
4% of jobs
$81.3K - $90.1K
3% of jobs
$90.1K - $98.9K
2% of jobs
$98.9K - $107.7K
1% of jobs
$107.7K - $116.5K
1% of jobs
$19.6K
$57.1K
$116.5K
How much do manager manager jobs pay per year?
What are the key skills and qualifications needed to thrive as a Manager, and why are they important?
What is the highest paying manager position?
What jobs in the US pay 300,000 a year?
What are the manager positions?
What does a management manager do?
What is the difference between Manager Manager vs Project Manager?
| Aspect | Manager Manager | Project Manager |
|---|---|---|
| Required Credentials | Bachelor's degree, management experience | Bachelor's degree, project management certification (e.g., PMP) |
| Work Environment | Oversees teams, departments, or divisions within organizations | Plans, executes, and closes projects across various industries |
| Employer & Industry Usage | Common in corporate, retail, and service sectors | Widely used in construction, IT, engineering, and consulting |
| Search & Comparison Intent | Often compared for leadership roles within organizations | Compared for managing specific projects and deadlines |
The main difference is that a Manager Manager oversees ongoing operations and teams within a company, focusing on long-term goals, while a Project Manager handles specific projects with defined start and end points. Both roles require leadership skills, but their scope and focus differ significantly.
How do Manager Managers typically balance overseeing their own teams while also supporting other managers within the organization?

Full-time
Posted 4 days ago
Job description
The Sr. Manager/Manager, Manufacturing will serve as a key operational leader at GeneFab, partnering closely with MSAT, Quality Assurance, Quality Control, Supply Chain, Facilities and Process Development to ensure manufacturing readiness, GMP compliance, and continuous improvement across all client programs. This individual will be expected to operate with strong ownership and accountability, driving both team performance and operational excellence while maintaining the highest standards of patient safety and product quality.
This is a hands-on operational role requiring significant on-the-floor presence and direct Gemba of manufacturing areas during processing runs.
Key Responsibilities:
The Sr. Manager/Manager, Manufacturing is expected to maintain a strong operational presence in the manufacturing suites and support areas, actively observing and engaging in daily GMP operations. Key responsibilities include:
- Lead and manage daily cGMP manufacturing operations across cell and gene therapy programs, ensuring all activities are executed in compliance with approved batch records, SOPs, and applicable regulatory requirements.
- Build, develop, and retain a high-performing manufacturing team; hire, onboard, mentor, and conduct performance reviews for manufacturing specialists, senior associates, and supervisors.
- Champion a culture of quality, patient safety, and operational excellence across all manufacturing activities, ensuring team members always understand and uphold cGMP standards.
- Partner with MSAT to plan and execute Engineering Runs and Technology Transfer Runs for new client programs introduced to the site, supporting smooth transitions from process development to GMP manufacturing.
- Collaborate with Quality Assurance to ensure on-time closure of deviations, CAPAs, and change controls; serve as manufacturing owner for investigations and provide thorough, technically sound root cause analyses.
- Review and approve GMP-controlled documents including standard operating procedures, master batch records, material specifications, training materials, and validation protocols and reports.
- Develop and maintain a comprehensive training program for cGMP operations and manufacturing systems, ensuring all staff achieve and sustain the competency level required for multi-product clinical manufacturing.
- Manage manufacturing scheduling, ensuring people, facility, equipment, materials, and documentation are aligned and available to support program timelines and site capacity requirements.
- Oversee and provide direct on-the-floor operational support during all manufacturing runs and processing activities; maintain regular Gemba walks through manufacturing suites and support areas to observe operations firsthand, identify improvement opportunities, and ensure compliance with procedures and cGMP practices.
- Drive continuous improvement initiatives aimed at increasing right-first-time performance, reducing operational cycle times, and improving overall manufacturing efficiency.
- Develop, track, and report departmental KPIs; present operational performance updates and contribute to the development of annual department goals and budgets.
- Support capacity planning for clinical and commercial manufacturing campaigns; proactively identify and escalate resourcing or scheduling risks that could impact client program delivery.
- Build and maintain effective cross-functional partnerships with Quality, Supply Chain, MSAT, EHS, Facilities and Engineering, and client teams to ensure alignment and seamless execution across all operational activities.
- Support regulatory inspection readiness activities including internal audits, mock inspections, and preparation of manufacturing areas and documentation for FDA, EMA, or other agency inspections.
Supervisory Responsibilities:
- Hire, mentor, and develop exceptional manufacturing talent at all levels, from entry-level associates to senior supervisors.
- Conduct regular performance reviews and identify opportunities for career growth, skills development, and advancement.
- Foster a culture of collaboration, cross-functional inclusion, execution excellence, and effective communication to build a high-performing manufacturing team.
- Provide clear direction, coaching, and accountability to direct reports; resolve team conflicts and performance issues in a timely and constructive manner.
Qualifications:
- Bachelor's degree in a relevant science or engineering discipline required; advanced degree (M.S. or Ph.D.) preferred.
- Minimum of 6 years of relevant work experience within a pharmaceutical, biotechnology, or similarly regulated industry, including at least 5 years of direct hands-on experience in cGMP biologics or cell and gene therapy manufacturing.
- Minimum of 3 years of experience in a supervisory or management role with direct people leadership responsibility.
- Experience in cell and gene therapy manufacturing (autologous or allogeneic cell therapy, lentiviral or AAV viral vector production) is strongly preferred; CDMO experience is a significant plus.
- Strong technical writing capability with demonstrated experience authoring, reviewing, approving, and training staff on SOPs, batch records, change controls, deviations, and CAPAs.
- Thorough knowledge of cGMP regulations and regulatory guidelines including 21 CFR Parts 210/211/600/610 and EU GMP, with a demonstrated track record of maintaining compliance in a regulated manufacturing environment.
- Proven leadership ability to make sound decisions under pressure, manage competing priorities, and drive accountability across a manufacturing team in a dynamic, multi-program environment.
- Strong interpersonal and communication skills with the ability to build effective relationships across functions and engage and influence team members in a matrixed organization.
- Proficient in MS Office applications; familiarity with electronic batch record (EBR), manufacturing execution system (MES), and quality management system (QMS) platforms preferred.
Compensation:
- Compensation range for Manager: 140-160K
- Compensation range for Sr. Manager: 160-180K
$140,000 - $180,000 a year
About GeneFab
GeneFab is a contract manufacturing and synthetic biology biofoundry focused on cell and gene therapies. GeneFab was formed in 2023 with a vision to combine industry leading expertise in synthetic biology with advanced cGMP capabilities in order to accelerate the development and commercialization of genetic medicines. GeneFab offers its customers an extensive technology platform and know-how that spans early stage product design, technical development, and cGMP compliant production. GeneFab's technology platform includes bioinformatic-guided discovery of cell type promoters, directed evolution of small molecule-regulated gene switches, and the engineering of highly sensitive kill switches for enhanced safety and control of cellular therapies.
We are committed to an inclusive and diverse GeneFab. We believe that different perspectives lead to better ideas, and better ideas allow us to better understand the needs and interests of our diverse GeneFab team. We welcome people of different backgrounds, experiences, abilities, and perspectives and are an equal opportunity employer.
We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.