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Locum Rn Jobs in Charleston, SC (NOW HIRING)

PRN Healthcare

Travel OR RN

Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

PRN Healthcare is seeking a travel nurse RN OR - Operating Room for a travel nursing job in ... locum tenens, CNAs, and more. This lead to the introduction of PRN Healthcare, which is inclusive ...

PRN Healthcare

Travel OR RN

Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

PRN Healthcare is seeking a travel nurse RN OR - Operating Room for a travel nursing job in ... locum tenens, CNAs, and more. This lead to the introduction of PRN Healthcare, which is inclusive ...

PRN Healthcare

Travel OR RN

Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

PRN Healthcare is seeking a travel nurse RN OR - Operating Room for a travel nursing job in ... locum tenens, CNAs, and more. This lead to the introduction of PRN Healthcare, which is inclusive ...

Solomon Page

Travel Electrophysiology RN

Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Retirement

... nurses, locum tenens, and allied resources. For more information and additional healthcare ... Posted job title: nurse - rn - ep | charleston, south carolina About Solomon Page Founded in 1990 ...

PRN Healthcare

Travel CVICU RN

Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Discipline: RN * Start Date: 08/24/2026 * Duration: 13 weeks * 40 hours per week * Shift: 8 hours ... locum tenens, CNAs, and more. This lead to the introduction of PRN Healthcare, which is inclusive ...

RN.com

Dentist

Summerville, SC · On-site

$111 - $166/hr

AMN Locums Dentistry has been successfully providing locum tenens coverage for over 20 years, across 47 states, matching Dentists to their ideal jobs. With over 39 years of combined Dentistry ...

MUSC Health West Ashley Medical Pavilion

RN - OR

Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Registered Nurse Operating Room Position is for an Ambulatory OR RN. The shift is 10 hours from 06 ... nursing, allied health, locum tenens, pharmacy, therapy, direct‑hire, and non‑clinical ...

New

University Medical Center

RN - OR

Charleston, SC · On-site

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Registered Nurse Operating Room Job Title: Registered Nurse Profession: Nursing Specialty ... nursing, allied health, locum tenens, pharmacy, therapy, direct‑hire, and non‑clinical ...

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All JobsLocum Rn JobsLocum Rn Jobs in Charleston, SC

Locum Rn information

What are some common challenges faced by Locum RNs when adapting to new clinical settings?

Locum RNs often encounter unique challenges when integrating into unfamiliar healthcare environments, such as quickly learning new protocols, adapting to different electronic health record systems, and building rapport with established teams. Flexibility and strong communication skills are essential, as locum nurses must efficiently assess patient needs while adhering to facility-specific procedures. Despite these challenges, many locum RNs find the variety and exposure to diverse practices rewarding, and these experiences can strengthen their clinical versatility.

What are the key skills and qualifications needed to thrive as a Locum RN?

To thrive as a Locum Registered Nurse (RN), you need a current RN license, a solid background in clinical care, and experience adapting quickly to new healthcare environments. Familiarity with various electronic health record (EHR) systems and up-to-date certifications such as BLS or ACLS are typically required. Strong communication, adaptability, and problem-solving skills help locum RNs integrate smoothly into diverse teams and deliver quality patient care. These competencies are crucial for providing consistent, high-quality nursing support across different facilities and ensuring patient safety during temporary assignments.

What is the difference between Locum Rn vs Staff Rn?

AspectLocum RnStaff Rn
CredentialsRegistered Nurse license, possibly specialized certificationsRegistered Nurse license, possibly specialized certifications
Work EnvironmentTemporary assignments in various healthcare settingsFull-time or part-time employment in a specific healthcare facility
Employer UsageStaffing agencies, hospitals, clinicsHospitals, clinics, healthcare facilities
Search IntentTemporary nursing jobs, short-term assignmentsPermanent or long-term nursing positions

In summary, a Locum Rn is a temporary nurse filling short-term staffing needs, often through agencies, while a Staff Rn is a full-time or part-time employee working consistently at a healthcare facility. Both roles require valid RN licensure and similar certifications, but their employment types and work environments differ significantly.

What is a Locum RN?

A Locum RN, or Locum Registered Nurse, is a qualified nurse who temporarily fills staffing gaps in healthcare facilities, such as hospitals, clinics, or nursing homes. They may cover for permanent staff members who are on leave, or help during periods of increased patient demand. Locum RNs perform all the standard duties of a registered nurse, including patient care, administering medications, and collaborating with healthcare teams. This type of work offers flexibility and the opportunity to gain experience in different clinical environments.

What are the most commonly searched types of Rn jobs in Charleston, SC?

The most popular types of Rn jobs in Charleston, SC are:

What are popular job titles related to Locum Rn jobs in Charleston, SC?

For Locum Rn jobs in Charleston, SC, the most frequently searched job titles are:

What job categories do people searching Locum Rn jobs in Charleston, SC look for?

The top searched job categories for Locum Rn jobs in Charleston, SC are:

What cities near Charleston, SC are hiring for Locum Rn jobs?

Cities near Charleston, SC with the most Locum Rn job openings:

Locum Rn jobs near you
Infographic showing various Locum Rn job openings in Charleston, SC as of August 2026, with employment types broken down into 3% As Needed, 57% Full Time, 15% Part Time, and 25% Contract. Highlights an 96% Physical, and 4% Remote job distribution.

Travel OR RN

PRN Healthcare

Charleston, SC • On-site

Contractor

Medical, Dental, Vision, Life, Retirement

Posted 23 days ago

Job description

PRN Healthcare is seeking a travel nurse RN OR - Operating Room for a travel nursing job in Charleston, South Carolina.

Job Description & Requirements
  • Specialty: OR - Operating Room
  • Discipline: RN
  • Start Date: 08/31/2026
  • Duration: 13 weeks
  • 36 hours per week
  • Shift: 12 hours, days
  • Employment Type: Travel

PRN Healthcare Job ID #1573424. Pay package is based on 12 hour shifts and 36 hours per week (subject to confirmation) with tax-free stipend amount to be determined. Posted job title: OR RN

About PRN Healthcare

Our story starts with a 21-year-old CNA named Pete Hietpas. Pete was diligently working in eastern Wisconsin with a variety of staffing agencies, but something was missing. He loved caring for his patients, but felt that staffing agencies were exchanging compassion for competitiveness. He was determined to change that. As a result, he started Nurses PRN in 1995 to become a model for the healthcare staffing industry – being competitive in the marketplace, yet still maintaining a compassionate heart.


Over the years Nurses PRN grew and evolved as a nationwide healthcare staffing company, and therefore wanted to be more inclusive to all valued healthcare professionals: nurses, allied health, locum tenens, CNAs, and more. This lead to the introduction of PRN Healthcare, which is inclusive of Nurses PRN and all of our other healthcare divisions.


Our mission to create authentic, meaningful relationships with our healthcare professionals helps us set them up for success in their dream assignment, whether that be a travel contract, local contract, or per diem shift. This is all driven by the simple idea that better care for our healthcare workers, leads to better patient care – and this is all supported by a dedicated internal staff.


Our company culture is strongly backed by faith-based values and activities, to remind us that our success provides us the opportunity to serve and give back to our communities. This is the spirit of caregiving. This is PRN Healthcare.

Benefits
  • Weekly pay
  • Guaranteed Hours
  • Continuing Education
  • 401k retirement plan
  • Referral bonus
  • Employee assistance programs
  • Company provided housing options
  • Medical benefits
  • Dental benefits
  • Vision benefits
  • Life insurance
PRN Healthcare logo

About PRN Healthcare

Sourced by ZipRecruiter

As a result, he started Nurses PRN in 1995 to become a model for the healthcare staffing industry - being competitive in the marketplace, yet still maintaining a compassionate heart. Over the years Nurses PRN grew and evolved as a nationwide healthcare staffing company, and therefore wanted to be more inclusive to all valued healthcare professionals: nurses, allied health, locum tenens, CNAs, and more. This lead to the introduction of PRN Healthcare, which is inclusive of Nurses PRN and all of our other healthcare divisions. Our mission to create authentic, meaningful relationships with our healthcare professionals helps us set them up for success in their dream assignment, whether that be a travel contract, local contract, or per diem shift. This is all driven by the simple idea that better care for our healthcare workers, leads to better patient care - and this is all supported by a dedicated internal staff. Our company culture is strongly backed by faith-based values and activities, to remind us that our success provides us the opportunity to serve and give back to our communities.

Industry

Recruiting and staffing services

Company size

501 - 1,000 Employees

Headquarters location

Appleton, WI, US

Year founded

1995

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