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As of Jul 1, 2026, the average hourly pay for lis analyst in the United States is $30.38, according to ZipRecruiter salary data. Most workers in this role earn between $20.43 and $36.06 per hour, depending on experience, location, and employer.

What is a LIS Analyst job?

A LIS (Laboratory Information System) Analyst is responsible for managing, maintaining, and optimizing laboratory information systems that support healthcare and diagnostic laboratories. They configure software, troubleshoot system issues, integrate LIS with other healthcare technologies, and ensure data accuracy and compliance with regulations. LIS Analysts collaborate with laboratory staff, IT teams, and vendors to enhance system functionality and streamline workflows. Their role is essential for improving lab efficiency, data management, and patient care.

What are the key skills and qualifications needed to thrive in the Lis Analyst position, and why are they important?

To thrive as a LIS Analyst, you need a solid background in laboratory science, information systems, and data analysis, typically supported by a degree in medical technology, information systems, or a related field. Familiarity with Laboratory Information Systems (LIS) such as Cerner, Sunquest, or Epic Beaker, as well as relevant certifications like ASCP, are often required. Strong problem-solving skills, attention to detail, and effective communication abilities are valuable soft skills in this position. These skills help ensure reliable lab operations, accurate data management, and seamless collaboration between IT teams and laboratory staff.

What does a typical day look like for a LIS Analyst, and with whom do they collaborate most frequently?

A typical day for a LIS Analyst involves monitoring, troubleshooting, and optimizing laboratory information systems to ensure seamless data flow and accurate reporting. You will regularly interact with laboratory technologists, IT professionals, and sometimes clinicians to address system issues, implement updates, and support workflow enhancements. The role may require you to participate in meetings regarding lab process improvements, validate system changes, and provide end-user training. Effective teamwork and communication are essential, as LIS Analysts serve as a bridge between technical teams and laboratory operations. This collaborative environment helps deliver timely, high-quality patient results and supports ongoing improvements in lab efficiency.

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Infographic showing various Lis Analyst job openings in the United States as of June 2026, with employment types broken down into 99% Full Time, and 1% Part Time. Highlights an 81% Physical, 7% Hybrid, and 12% Remote job distribution, with an average salary of $63,187 per year, or $30.4 per hour.
LIS Applications Analyst: 40 Hours Per Week (AM)

LIS Applications Analyst: 40 Hours Per Week (AM)

Alverno Laboratories

Hammond, IN

Full-time

Posted 11 days ago

Alverno Laboratories rating

6.6

Company rating: 6.6 out of 10

Based on 17 frontline employees who took The Breakroom Quiz

78th of 103 rated laboratories

Job description

Central Laboratory - Management Information Services

Location: 2434 Interstate Plaza Dr, Hammond, IN 46324

Shift: Days; Monday - Friday

FTE: 1.0

WHY ALVERNO

We are a highly reliable scientific organization building a culture of service. Our commitment advances the health, wellness and continuity of care in the communities we serve. We are one of the largest integrated laboratory networks serving hospitals in the Midwest region. Our network includes 32 hospitals and multiple physician offices.

WHAT WILL YOU DO

This individual implements, maintains, and supports the Laboratory Information System (LIS) and other software products used to support Alverno Clinical Laboratories, LLC and Alverno Provena Hospital Labs.
The Applications Analyst is responsible for analysis of current LIS functionality; identification and implementation of unused and new components of the LIS; implementation, validation, support and maintenance activities of the LIS; maintenance and validation of the LIS components of all partner hospital information systems and SSFHS owned Physician Office Systems as necessary; and development and maintenance of procedures and documentation required for regulatory agencies. This individual shall maintain a healing environment for employees and patients with a spirit of caring and concern as incorporated in the philosophy of the supporting Catholic Health Ministries while performing all job functions.
WHAT WE ARE LOOKING FOR

Required education for this role includes one of the following:

Bachelor's degree in information systems, Information Technology, Computer Science or related field.

Bachelor's degree in medical or clinical sciences; or Medical Technologist certification.

Professional Experience: Minimum five (5) years' experience working in a highly complex clinical laboratory environment, including:

Four (4) years' experience using and supporting a Laboratory Information System.

Experience with HIS (Hospital Information System), EHR/EMR (Electronic Health / Medical Records), Reference Lab and instrument interfaces and / or report writing preferred.

Must demonstrate very good technical, analytical and problem-solving skills.

Must demonstrate and enforce very good customer service, team building and written / verbal communication skills to work effectively in integrated lab setting.

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