Executive Manager Jobs in Rochester, MN (NOW HIRING)

Mayo Clinic is currently seeking a highly skilled and experienced Executive Administrator for the Mayo Clinic Comprehensive Cancer Center (MCCCC). This individual, in partnership with the Executive Director of the MCCCC, is responsible for strategic and operational planning, leadership development, staff diversity, fiscal management, and monitoring of operational and performance outcomes of the MCCCC in alignment with Mayo Clinic's overall strategy. 

At Mayo Clinic Comprehensive Cancer Center (MCCCC), our mission is bold: to cure cancer. As a leading global authority, we are transforming cancer research, practice, and education and training with category-of-one data platforms, artificial intelligence (AI), automation, and digital technologies. Through our developing digital front door (My Mayo Clinic) and our innovative Cancer Care Beyond Walls (CCBWTM) and Clinical Trials Beyond Walls (CCBWTM) programs, we are assuring Mayo Clinic discoveries, knowledge and expertise are accessible to all, within and beyond our walls, at any place or anytime.  

Designated as one of the nation's highest-ranked National Cancer Institute (NCI)-Designated Comprehensive Cancer Centers since 1973, MCCCC is the only NCI Cancer Center with three highly integrated sites-Rochester, Minnesota; Jacksonville, Florida; and Phoenix and Scottsdale, Arizona - treating more than 150,000 unique patients with cancer from across the nation annually. Mayo Clinic and MCCCC also have a fourth health delivery system: Mayo Clinic Health System (MCHS). This community-based primarily rural health care delivery system extends from the Rochester campus through 49 communities in southern Minnesota, western Wisconsin, and northeastern Iowa. The constellation of the three Mayo Clinic campuses and MCHS, each with unique opportunities and catchment area populations, creates a remarkable opportunity to develop models for collaborative research, distributed clinical trials, and cancer care delivery between academic and community-based healthcare providers.

MCCCC is also particularly distinguished among the nation's cancer centers by our unparalleled opportunities to transform research and clinical practice through extensive collaborations with the Mayo Clinic AI Program, extensive cloud-based and on premises computing capabilities, and Mayo Clinic Platform (MCP) - the world's largest collaborative, distributed, federated healthcare data network with a cloud-based data architecture holding the longitudinal healthcare records of 54 million patients from across the world. 

The Executive Administrator also serves as the Enterprise Deputy Director for Administration for the Mayo Clinic NCI P30 Cancer Center Support Grant (CCSG), in partnership with the MCCCC Executive Director who serves as the CCSG Principal Investigator. In this role, the Executive Director oversees an administrative team that supports the center's leadership, faculty, and staff teams who guide each CCSG component. The Executive Administrator works closely with Center's Deputy Directors, site-based leaders, and allied health care staff to drive a high-performance collaborative research ecosystem in our laboratories, clinics and communities. Six Research Programs serve as engines for scientific discovery, translating our discoveries to novel diagnostics and therapeutics. These six transdisciplinary Research Programs include: Cancer Genomics, Signaling, and Metastasis (CGSM), Cancer Immunology and Immunotherapeutics (CII), Cancer Risk Assessment, Early Detection, Interception (REDI), Cancer Prevention, Control, and Survivorship (CPCS), Novel Therapeutics and Therapeutic Modalities (NTTM) and Advanced Clinical Trials and Translational Sciences (ACTS). Through collaborations and coordination with the Mayo Clinic Research Sheild, MCCCC harnesses the power of these Research Programs, seven Translational Science teams, and 15 Disease Groups to drive a highly robust cancer clinical trials program, with distributed and decentralized elements. Center activities are also supported by 15 outstanding Shared Research Resources. Through these efforts, MCCCC is revolutionizing cancer research and pioneering new ways to detect, intercept, and advance cures for patients with cancer everywhere. 

This is an on-site position based in Rochester, MN.

Destination Medical Center Campuses

Rochester, Minnesota: 

Mayo Clinic is located in the heart of downtownRochester, Minnesota, a dynamic city just 75 minutes south of the Twin Cities of Minneapolis and St. Paul. The city is consistently ranked among the best places to live in the United States because of its affordable cost of living, healthy lifestyle, excellent school systems and exceptionally high quality of life.Rochesteris changing to become the world's premier destination medical center as new buildings fill the skyline that pave the way for initiatives that are unleashing fresh possibilities and make the city a fantastic place to learn, live and play. Distinguished by its culture of caring, spirit of innovation, and fascinating history, Rochester is renowned for its scenic beauty, relaxing pace, and abundant dining, shopping, and entertainment options. 

The Bold. Forward. Unbound. initiative is a $5 billion, six-year transformation of Mayo Clinic's downtown Rochester campus, adding approximately2.4 million square feetacross five new buildings. This includes significant new space for integrated in-patient and out-patient cancer care delivery and delivery of new and novel therapeutics. This expansion reimagines care delivery through flexible, future-oriented designs such as adaptable clinical spaces and integrated digital technologies.The initiative also involves extensive infrastructure upgrades and phased demolition to support a more connected, patient-centered environment. 

To stimulate the translation of discovery science to human applications, facilitate collaboration with biotechnology industry, and expand innovation networks, Mayo Clinic has developed biotechnology research parks and healthcare innovation districts adjacent to each Mayo Clinic campus.Discovery Squareis a 16-block district of downtown Rochester, fostering collaborations between biotech industries and MCR investigators. One Discovery Square opened in 2019 with infrastructure for wet and dry laboratories and houses the Mayo Clinic Center for Regenerative Biotherapeutics (CRB). CRB is producing several novel cancer therapeutics (gene and virus therapies, cancer vaccines, novel CAR-T agents) which are being tested by Mayo Clinic investigators in clinical trials. In addition to CRB, Discovery Square is now home to 35 biotechnology companies, including Boston Scientific and Phillips.

Phoenix/Scottsdale, Arizona: 

Over the next four years,Mayo Clinic is making significant investments in both the physical and technological future of health care, through doubling the size of the Mayo Clinic campus in Phoenix, inclusive of practice, education, and research activities. A 120-acre biotechnology corridor calledDiscovery Oasisis currently in development. Biotech innovators will be invited to co-locate in the biotech corridor and contribute to a new collaborative. Arizona State University, the first collaborator in the corridor, is a proven asset in the development of a world-class talent pipeline that is feeding the growing healthcare technology sector in Arizona. 

Jacksonville, Florida: 

The Mayo Clinic Florida campus recently completed a major hospital expansion that includes the opening of the Duan Family Building on July 7, 2025. This 228,000-square-foot facility introduces the first carbon ion therapy program in the Western Hemisphere, expected to begin treating patients in 2028 pending FDA approval. The Center's expanded proton radiation therapy program will open in February of 2027. Mayo Clinic has recently acquired 201 acres north of the current 392-acre campus to establish a Healthcare Innovation District and Biotechnology Park:Discovery Coast.The goals of Discovery Coast are to: 1) Accelerate the Bold. Forward. 2030 Strategy; 2) Generate and Diversify Income; and 3) Advance Translational Research and Academic Partnerships particularly in cancer and neurologic disorders. This innovation hub will enable the development of talent and expertise, extending influence throughout the campus, across the North Florida region, and beyond. Discovery Coast is envisioned to serve as a unique healthcare ecosystem leveraging advanced technologies and fostering immersive learning/testing environments to develop a community that creates novel discoveries and partnerships.

A master's degree in business or health care administration is required. Candidates must have at least five years of substantial leadership and management experience; 10 years is preferred. This experience must include working with physicians, scientific investigators, and allied health staff across a variety of assignments. Candidates must demonstrate expertise in leadership, management, operations, finance, and communication. Broad senior-management experience is required to coordinate activities across the organization, along with in-depth knowledge of Mayo Clinic's strategic priorities and a broad understanding of the institution's strengths and weaknesses relevant to advancing those priorities. Scientific expertise and experience in research and clinical trial operations within an NCI-designated cancer center are strongly preferred.