Speak with your direct manager to discuss your interest and alignment with your development goals ... preclinical gene therapy pipeline. The Research Associate II will work closely with scientists ...
Speak with your direct manager to discuss your interest and alignment with your development goals ... preclinical gene therapy pipeline. The Research Associate II will work closely with scientists ...
Director Preclinical Development information
See Raleigh, NC salary details
$39.4K - $49.5K
5% of jobs
$49.5K - $59.6K
9% of jobs
$67.2K is the 25th percentile. Wages below this are outliers.
$59.6K - $69.7K
15% of jobs
$69.7K - $79.8K
16% of jobs
The median wage is $83.2K / yr.
$79.8K - $90K
16% of jobs
$90K - $100.1K
14% of jobs
$100.6K is the 75th percentile. Wages above this are outliers.
$100.1K - $110.2K
10% of jobs
$110.2K - $120.3K
6% of jobs
$120.3K - $130.4K
4% of jobs
$130.4K - $140.6K
3% of jobs
$140.6K - $150.7K
2% of jobs
$39.4K
$89.8K
$150.7K
How much do director preclinical development jobs pay per year?
What is a Director Preclinical Development job?
A Director of Preclinical Development oversees the early-stage research and testing of drug candidates before they enter clinical trials. They manage preclinical studies, ensuring regulatory compliance, safety, and efficacy assessments. This role involves coordinating with cross-functional teams, external partners, and regulatory agencies to advance promising compounds. Strong expertise in toxicology, pharmacology, and regulatory guidelines is essential. The director plays a key role in shaping the preclinical strategy to support successful drug development.
What are the key skills and qualifications needed to thrive in the Director Preclinical Development position, and why are they important?
To thrive as a Director Preclinical Development, you need deep expertise in pharmaceutical or biotechnology research, strong project management abilities, and an advanced degree (Ph.D., Pharm.D., or equivalent) in a life sciences field. Familiarity with regulatory guidelines (such as GLP), experience using data management and statistical analysis software, and prior leadership roles in preclinical studies are essential. Exceptional communication, problem-solving, and team leadership skills set candidates apart in managing multidisciplinary teams and collaborative projects. These competencies are crucial for successfully guiding drug candidates through preclinical stages while ensuring regulatory compliance and timely project delivery.
What are the typical responsibilities and team dynamics for a Director of Preclinical Development?
A Director of Preclinical Development is responsible for overseeing the planning, execution, and management of preclinical research programs, ensuring that studies meet scientific, regulatory, and project milestones. You will typically work with cross-functional teams including toxicologists, pharmacologists, regulatory affairs professionals, and external partners, fostering collaboration throughout the drug development process. The role often involves reviewing study designs and data, preparing regulatory submissions, and providing strategic direction to advance compounds toward clinical testing. Working closely with upper management, you'll play a key part in shaping research priorities and resource allocation. This position offers significant influence over drug development strategies and opportunities for advancement to higher executive or scientific leadership roles.

Full-time
Re-posted 3 days ago
Job description
We're pleased to share an exciting secondment opportunity at AskBio.
This role is available for a time period to be determined by leadership at both Bayer and AskBio. While most assignments range from one to two years, the exact duration will be based on business needs and mutual agreement.
This secondment offers a unique chance to broaden your experience, expand your knowledge, and contribute meaningfully to AskBio's mission: to advance gene therapy and change the lives of patients around the world.
If you're interested in exploring this opportunity, we encourage you to:
Speak with your direct manager to discuss your interest and alignment with your development goals.
Apply directly using the link provided in the posting.
We look forward to seeing how our colleagues continue to grow and make an impact across the Bayer-AskBio partnership.
Our vision: Pioneering science to create transformative molecular medicines.
Our mission: Lead innovative science and drive clinical outcomes to transform people's lives.
Our principles:
Advance innovative science by pushing boundaries.
Bring transformative therapeutics to patients in need.
Provide an environment for employees to reach their fullest potential.
Our values:
Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.
Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view.
Embrace Responsibility. We are humbled by the enormity of our mission.We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers.
Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.
Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what's right in every situation. Make clear commitments and follow through.
Position Summary
AskBio is seeking a motivated, detail-oriented, and collaborative Research Associate II to support AAV delivery research within the Delivery organization in R&D. This role provides hands-on experimental support across molecular biology and cell-based workflows that advance AskBio's preclinical gene therapy pipeline. The Research Associate II will work closely with scientists within the Delivery team to execute established experimental protocols with increasing independence, generate high-quality and reproducible data, and support day-to-day laboratory operations.
This position is based in Morrisville, North Carolina.
Job Responsibilities
Perform plasmid purification, genomic DNA extraction, RNA extraction, and PCR-based assays (PCR, qPCR, ddPCR)
Conduct routine mammalian cell culture activities, including maintenance of adherent cell lines and execution of cell-based assays following established SOPs
Perform in vitro assays including transfection and AAV transduction
Support in vitro and in vivo studies through sample preparation, tissue processing, and downstream molecular analyses
Accurately document experimental procedures and results in an electronic laboratory notebook in accordance with data integrity standards
Analyze data, summarize results, and communicate findings through internal reports or presentations
Maintain laboratory organization, including reagent preparation, inventory management, and inspection readiness
Contribute to continuous improvement of laboratory workflows by following SOPs and escalating issues appropriately
Minimum Requirements
Bachelor's degree in Molecular Biology, Biochemistry, Biotechnology, or a related scientific field with 2+ years of relevant laboratory experience; OR a Master's degree in Molecular Biology, Biochemistry, Biotechnology, or a related scientific field
Hands-on experience with molecular biology techniques, including DNA/RNA isolation, SDS-PAGE, qPCR, ddPCR and Western blot
Prior experience with mammalian cell culture and aseptic technique
Strong technical laboratory skills with the ability to independently execute protocols and experiments
Ability to follow established protocols with minimal supervision and deliver reliable, reproducible results
Strong organizational skills, attention to detail, and commitment to accurate documentation
Ability to manage multiple tasks simultaneously and work effectively within a collaborative, crossfunctional team environment
Proficiency with basic data analysis and common laboratory software tools (e.g., Excel, GraphPad)
Preferred Education, Experience and Skills
Experience supporting AAV research or delivery programs, including familiarity with viral vectors or gene therapy concepts
Exposure to AAV production or purification workflows at a research scale
Experience preparing samples for downstream analyses such as NGS or other advanced molecular assays
Comfort working across diverse experimental workflows and learning new techniques as project needs evolve
AskBio Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid jobrelated requirements. If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at (919) 561-6210 or sending us an email at talent@askbio.com.