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Evommune, Inc.

Director, DMPK

Palo Alto, CA · On-site

The Director, DMPK will serve as the DMPK program lead, responsible for establishing and executing ADME, PK, and PK-PD strategies that inform candidate selection, IND-enabling activities, and first ...

Atavistik Bio

Senior Scientist, DMPK

Cambridge, MA · On-site

$107K - $137K/yr

Reporting to the Senior Director, DMPK, this individual will be responsible for the design, execution, reviewing and interpreting the non-clinical DMPK data. This work supports the progression of ...

Atavistik Bio

Senior Scientist, DMPK

Cambridge, MA

$130K - $150K/yr

Reporting to the Senior Director, DMPK, this individual will be responsible for the design, execution, reviewing and interpreting the non-clinical DMPK data. This work supports the progression of ...

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How much do director dmpk jobs pay per year?

As of Jun 10, 2026, the average yearly pay for director dmpk in the United States is $246,666.00, according to ZipRecruiter salary data. Most workers in this role earn between $230,000.00 and $261,000.00 per year, depending on experience, location, and employer.

What are the main responsibilities of a Director DMPK and how do they interact with other departments?

A Director DMPK is responsible for leading the strategy, design, and execution of drug metabolism and pharmacokinetic studies supporting drug discovery and development. This role involves collaborating closely with medicinal chemistry, toxicology, clinical pharmacology, and regulatory affairs teams to ensure the safe and efficient progression of drug candidates. Directors often oversee the interpretation of preclinical and clinical PK data, provide scientific input for regulatory submissions, and contribute to project milestone decisions. Regular interaction with both internal project teams and external partners is common, making cross-functional communication a key aspect of daily work. This collaborative environment enables Directors to make significant contributions to successful drug development pipelines.

What does a Director of DMPK do?

A Director of Drug Metabolism and Pharmacokinetics (DMPK) leads efforts to understand the absorption, distribution, metabolism, and excretion (ADME) of drug candidates. They design and oversee preclinical and clinical studies to optimize drug properties, ensuring efficacy and safety. This role involves collaborating with pharmacology, toxicology, and regulatory teams to drive drug development. Additionally, they interpret data, guide strategy, and contribute to regulatory submissions.

What are the key skills and qualifications needed to thrive in the Director Dmpk position, and why are they important?

To thrive as a Director DMPK (Drug Metabolism and Pharmacokinetics), you need advanced expertise in pharmacokinetics, drug metabolism, and bioanalytical methods, typically supported by a PhD in pharmaceutical sciences, chemistry, or a related field. Familiarity with regulatory guidelines, data analysis platforms like WinNonlin or Phoenix, and validated laboratory systems is crucial. Strong leadership, cross-functional collaboration, and effective communication skills help in guiding multidisciplinary teams and driving complex projects forward. These capabilities ensure the development and regulatory success of new drug candidates in a highly competitive and compliant environment.

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Director Dmpk jobs near you
Director, DMPK

Director, DMPK

Evommune, Inc.

Palo Alto, CA • On-site

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 24 days ago

Job description

About Evommune, Inc.
Evommune, Inc. (NYSE: EVMN) is a clinical-stage biotechnology company focused on developing innovative therapies for immune-mediated inflammatory diseases. Headquartered in Palo Alto, California, with additional operations in New York, NY, Evommune is advancing a differentiated pipeline designed to address the underlying drivers of disease.
Our scientific approach integrates deep immunology expertise with disciplined clinical development to deliver potentially best-in-class therapies for patients with significant unmet medical needs. For more information, visit www.Evommune.com.
Work Location: This hybrid position is expected to be in the office two days per week, with the option to work remotely up to three days per week. Occasional additional onsite presence may be required based on business needs or operational priorities.
Our Core Values
Before we dive into the specifics of the role, it's important to highlight the core values that are integral to being a member of the Evommune team. Our values are not just words; they shape our culture, guide our decision-making, and define what it means to be part of our team.
  • Together We Win: We champion teamwork, celebrating every achievement as a shared success.
  • Guided by Insight: We make data-driven decisions, using our collective experience to shape the future of our business.
  • Every Day Matters: We act with urgency to bring transformative therapies to patients by being nimble, decisive, and effective.
  • Driven By Excellence: We set a high bar and hold ourselves accountable to deliver exceptional results in everything we do.
  • Empowered To Act: We invest in our team and value transparency, fostering trust and a sense of ownership.

We seek individuals who resonate with these principles, as they are essential for thriving in our collaborative, innovative, and dynamic work environment.
The Position
Evommune is hiring a Director, DMPK to provide scientific and strategic leadership across discovery and development programs. This role is critical to advancing our small-molecule pipeline from early discovery through clinical development.
The Director, DMPK will serve as the DMPK program lead, responsible for establishing and executing ADME, PK, and PK-PD strategies that inform candidate selection, IND-enabling activities, and first-in-human dose projections. As a subject-matter expert, this individual will partner closely with cross-functional teams to enable data-driven decision-making and efficient program execution.
This role reports to the Executive Director, Non-Clinical Development and offers the opportunity to play a visible, influential role in shaping Evommune's growing pipeline.
Key Responsibilities
  • Provide scientific and technical leadership for DMPK, PK, and PK-PD strategy across discovery and development programs
  • Serve as DMPK program lead, with accountability for study design, execution, interpretation, and reporting
  • Develop and implement DMPK strategies aligned with project and portfolio objectives, including candidate selection and first-in-human dose predictions.
  • Partner closely with Medicinal Chemistry, Pharmacology, Toxicology, CMC, Bioanalytical, and Clinical teams to support integrated program advancement
  • Oversee the design, analysis, and execution of in vivo and in vitro DMPK studies, ensuring timely communication of results to project teams and senior leadership
  • Provide expert interpretation of DMPK data and present findings to internal stakeholders and external partners
  • Author and/or oversee PK and DMPK sections of regulatory submissions (IND, IB, CTA, IMPD, NDA/BLA) and support regulatory interactions
  • Manage and collaborate with CROs, consultants, and external partners to ensure high-quality execution and efficient use of resources
  • Ensure scientific rigor, data integrity, and appropriate documentation across all DMPK activities
  • Support the continued evolution and scaling of DMPK capabilities as the pipeline grows

Qualifications
  • PhD in pharmacokinetics, drug metabolism, or a related discipline
  • 10+ years of small-molecule DMPK experience within the pharmaceutical or biotechnology industry
  • Proven track record of leading DMPK strategy for discovery and development programs
  • Deep expertise in ADME, PK, and PK-PD with experience translating preclinical data to clinical development
  • Experience with clinical candidate selection and first-in-human dose projections
  • Hands-on experience analyzing PK and PK-PD data using relevant modeling and analysis tools
  • Experience guiding the development and validation of bioanalytical methods for quantifying drug candidates and metabolites
  • Strong understanding of regulatory guidelines supporting small-molecule development, including preparation and review of DMPK sections for regulatory submissions
  • Experience supporting or leading interactions with U.S. and international regulatory agencies
  • Demonstrated ability to influence program strategy and decision-making through DMPK insight

How You Will Lead
  • Act as a trusted, influential partner to senior scientific and development leadership
  • Drive the DMPK agenda with strategic thinking, scientific rigor, and a bias toward action
  • Communicate complex data clearly and effectively to diverse audiences
  • Operate effectively in a fast-paced, resource-constrained, startup environment
  • Bring a collaborative, hands-on leadership style with strong problem-solving and analytical skills

Compensation
The salary range for this position is $190,000-$240,000, and the position may be eligible for performance-based bonuses and/or equity-linked compensation. Salary ranges are determined by role, level, and location, as well as additional factors such as job-related skills, experience, and relevant education or training. We offer Company-sponsored benefits, including comprehensive health, dental, and vision plans, as well as pet insurance. In addition, we offer a 401(k) plan, ample time-off programs, paid parental leave, life insurance, disability insurance, and an employee referral bonus program.
Evommune is proud to be an equal opportunity employer and will consider all qualified applicants for employment.
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About Evommune

Sourced by ZipRecruiter

Industry

Biotechnology research and development

Company size

1 - 10 Employees

Headquarters location

Sacramento, CA, US

Year founded

2020

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