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Dmpk Jobs (NOW HIRING)

Evommune, Inc.

Director, DMPK

Palo Alto, CA · On-site

The Director, DMPK will serve as the DMPK program lead, responsible for establishing and executing ADME, PK, and PK-PD strategies that inform candidate selection, IND-enabling activities, and first ...

Arvinas

DMPK Scientist

New Haven, CT · On-site +1

The incumbent will contribute as a DMPK scientist on project teams from drug discovery through all stages of drug development, with a scientific background on key aspects of DMPK science, including ...

Atavistik Bio

Senior Scientist, DMPK

Cambridge, MA

$107K - $137K/yr

We are seeking a Senior Scientist, DMPK, to join our R&D group and work with an enthusiastic team of highly skilled scientists in a fast-pace environment. Reporting to the Senior Director, DMPK, this ...

Exelixis

Senior DMPK Director

Alameda, CA

The Senior DMPK Director has strong scientific, technical and leadership skills to develop and implement DMPK and modeling & simulation strategies to advance drug candidates from discovery to ...

Vrtx

Executive Director, Biotherapeutics DMPK

Boston, MA

$268K - $402K/yr

This leader will be based in Boston but manage and oversee the work of DMPK-BA teams at our Vertex Biologics and Cell and Genetic Therapies sites in Boston and Seattle and will be part of the Global ...

Atavistik Bio

Senior Scientist, DMPK

Cambridge, MA · On-site

$130K - $150K/yr

We are seeking a Senior Scientist, DMPK, to join our R&D group and work with an enthusiastic team of highly skilled scientists in a fast-pace environment. Reporting to the Senior Director, DMPK, this ...

Exelixis

Senior DMPK Director

Alameda, CA · On-site

The Senior DMPK Director has strong scientific, technical and leadership skills to develop and implement DMPK and modeling & simulation strategies to advance drug candidates from discovery to ...

Exelixis

Senior DMPK Director

Alameda, CA

The Senior DMPK Director has strong scientific, technical and leadership skills to develop and implement DMPK and modeling & simulation strategies to advance drug candidates from discovery to ...

Atavistik Bio

Senior Scientist, DMPK

Cambridge, MA

$130K - $150K/yr

We are seeking a Senior Scientist, DMPK, to join our R&D group and work with an enthusiastic team of highly skilled scientists in a fast-pace environment. Reporting to the Senior Director, DMPK, this ...

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Dmpk information

See salary details

$57.5K

$191.3K

$230.5K

How much do dmpk jobs pay per year?

As of Jun 20, 2026, the average yearly pay for dmpk in the United States is $191,320.00, according to ZipRecruiter salary data. Most workers in this role earn between $135,500.00 and $229,000.00 per year, depending on experience, location, and employer.

What is a DMPK job?

A DMPK (Drug Metabolism and Pharmacokinetics) job involves studying how drugs are absorbed, distributed, metabolized, and excreted in the body. Professionals in this field assess drug interactions, optimize dosing strategies, and predict potential toxicity. They work closely with medicinal chemists, pharmacologists, and toxicologists to support drug discovery and development. DMPK scientists use analytical techniques such as mass spectrometry and in vitro/in vivo models to evaluate pharmacokinetic properties. Their work helps ensure the safety and efficacy of new therapeutics before clinical trials.

What are some typical challenges faced in a DMPK position and how are they addressed?

Professionals in DMPK roles often encounter the challenge of interpreting complex pharmacokinetic and metabolism data under tight project timelines. Coordinating data from various sources, troubleshooting analytical equipment, and keeping pace with evolving regulatory standards can demand adaptability and proactive problem-solving. Effective DMPK scientists collaborate closely with medicinal chemists, toxicologists, and clinical teams to ensure integrated drug development efforts. Many teams also have robust mentorship and training in place to help new hires navigate technical hurdles and develop their expertise. Overcoming these challenges requires a combination of technical rigor, teamwork, and ongoing professional development.

What are the key skills and qualifications needed to thrive in the Dmpk position, and why are they important?

To succeed in a DMPK (Drug Metabolism and Pharmacokinetics) role, you generally need advanced knowledge in pharmacology, biochemistry, and analytical chemistry, supported by a relevant advanced degree such as an MSc or PhD. Familiarity and hands-on experience with LC-MS/MS instrumentation, pharmacokinetic modeling software (such as Phoenix WinNonlin), and regulatory guidelines are highly valuable. Strong critical thinking, communication, and organizational skills help distinguish candidates, especially when interpreting data and collaborating with multidisciplinary teams. Mastery of these skills is essential for ensuring effective evaluation of drug candidates and clear communication of findings in a fast-paced research environment.

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Dmpk jobs near you
Infographic showing various Dmpk job openings in the United States as of June 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $191,320 per year, or $92 per hour.
DMPK Scientist, Bioanalytical

DMPK Scientist, Bioanalytical

Frontage Laboratories

Exton, PA • On-site

Full-time

Posted 15 days ago

Be an early applicant

Job description

ABOUT

Frontage Laboratories is a CRO / Clinical Research Organization providing integrated, science-driven, product development services throughout the drug discovery and development process to enable life science companies to achieve their drug development goals. We have enabled many innovator, generic and consumer health companies of all sizes to file IND, NDA, ANDA, BLA and 505(b)(2) submissions in global markets allowing for successful development of important therapies and products for patients. We are committed to providing rigorous scientific expertise to ensure the highest quality and compliance. We have successfully assisted clients to advance hundreds of molecules through development to commercial launch in global markets. Come and join us to make a world of difference.

DMPK

The DMPK/ Drug Metabolism and Pharmacokinetics group is dedicated to enabling the discovery, development and commercialization of safe and effective medicines by elucidating the absorption, distribution, metabolism, excretion and pharmacokinetic properties of small molecule drug candidates. We accomplish this through the application of state-of-the-art technologies and sciences of bioanalysis, drug metabolism, drug transport and pharmacokinetics. The DMPK group works in close partnership with disciplines such as medicinal chemistry, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to optimize leads, select clinical candidates, conduct preclinical development studies, support clinical evaluation and contribute to IND and NDA filings.

Position Summary

The department of Drug Metabolism and Pharmacokinetics (DMPK) at Frontage is seeking a highly motivated candidate with biology or chemistry background (BS, MS or PhD). This position requires an understanding of bioanalytical techniques. This person will work as a member of our DMPK drug development group and will be responsible for performing a variety of drug analysis of PK studies with guidance from senior members of the team. It is expected the individual selected for this position will receive appropriate trainings in handling radioactive compounds/samples and in the operation of analytical instruments such as HPLC and mass spectrometers.

Responsibilities

• Develop bioanalytical (especially) LC/MS/MS methods for discovery and development compounds

• Verify and qualify LC/MS/MS methods as needed for studies requiring more stringent bio-analytical criteria

• Work in a high pace environment in developing methods to analyze biological samples (e.g. plasma) from PK and in vitro metabolism studies requiring quantitative information.

• Assist in the preparation of study reports for studies involving bioanalysis of samples

• Ensure that all studies are conducted in a timely manner while maintaining highest quality of data

• Maintain a record of all studies in appropriate notebooks as per Frontage SOPs.

• Follow Frontage SOPs, DMPK guidelines, and study protocols while conducting studies.

• Ensure all laboratory operation and record-keeping are of high quality and compliant with Frontage SOPs or other applicable regulations.

• Work with Study Directors/Sponsors in study design, protocol preparation, and overseeing conduct of studies if needed.

• Effectively manage numerous tasks/projects simultaneously to meet internal/external deadlines while maintaining organizational integration within the DMPK team.

Requirements

• BS or MS or PhD with 0-3 years relevant experience in any of the pharmaceutical sciences including pharmacokinetics, in vitro and in vivo metabolism, mass spectrometry or analytical chemistry.

• Knowledge of LC/MS/MS analytical techniques will be a plus.

• Broad post-graduate experience in DMPK (for PhD positions) as demonstrated through publications will be a plus but not essential.

• Compensation commensurate with education and the experience.