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Clinical Operations Jobs in California (NOW HIRING)

Clinical Operations Support

Orange, CA ยท On-site

$19 - $23.50/hr

Clinical Operations Support II - Skincare Location: Irvine, CA - 100% Onsite Contract Duration: 12 Months, with potential for extension Experience: 3-5 Years Pay Rate: $19-$23.50/hr based on benefit ...

As Clinical Operations Manager, you will be the organizational backbone of site-level activity, ensuring every participating center is prepared, compliant, and ready to support patients receiving the ...

Clinical Operations Specialist (Remote) Turn data into meaningful action and help drive clinical excellence across a growing healthcare organization. Liberty Dental Plan is seeking a highly ...

As Clinical Operations Manager, you will be the organizational backbone of site-level activity, ensuring every participating center is prepared, compliant, and ready to support patients receiving the ...

Clinical Operations Lead

Mountain View, CA ยท On-site

$101K - $143K/yr

The Role We're looking for an RN with deep experience building digital clinical operations to help design and scale the operational backbone of our care program. This is not a traditional nursing ...

A strategic and hands-on Clinical Operations Manager responsible for overseeing clinical trials for medical devices while driving process remediation and operational excellence. This role requires a ...

Manager, Clinical Operations

Carlsbad, CA ยท On-site

$86K - $216K/yr

Ensures that staff are meeting defined workload and quality metrics through regular review and reporting of findings as outlined by clinical operations management. May collaborate with other clinical ...

Showing results 21-40

Clinical Operations information

See California salary details

$34.5K

$96.8K

$184.1K

How much do clinical operations jobs pay per year?

As of Sep 4, 2026, the average yearly pay for clinical operations in California is $96,755.00, according to ZipRecruiter salary data. Most workers in this role earn between $71,600.00 and $112,000.00 per year, depending on experience, location, and employer.

What is clinical operations?

Clinical operations refers to the planning, management, and execution of clinical trials and research studies within the healthcare and pharmaceutical industries. Professionals in clinical operations ensure that studies are conducted efficiently, ethically, and in compliance with regulatory requirements. Their responsibilities may include site management, patient recruitment, data collection, and ensuring protocol adherence. The goal is to facilitate the safe and effective development of new medical treatments and therapies.

How does a clinical operations professional typically collaborate with cross-functional teams during a clinical trial?

Clinical Operations professionals play a central role in coordinating activities among various teams such as regulatory affairs, data management, biostatistics, and clinical research associates. They ensure that timelines are met, protocols are followed, and all departments are aligned with trial objectives. Regular meetings, clear communication, and the ability to anticipate and resolve operational challenges are essential to successful collaboration. This cross-functional teamwork helps maintain trial quality and regulatory compliance throughout the study.

What are the key skills and qualifications needed to thrive in clinical operations, and why are they important?

To thrive in Clinical Operations, you need expertise in clinical trial management, regulatory compliance, and data analysis, typically supported by a degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), Good Clinical Practice (GCP) certification, and electronic data capture (EDC) platforms is essential. Strong leadership, problem-solving, and communication skills help coordinate teams and ensure project timelines are met. These skills are crucial for guaranteeing efficient, compliant, and successful clinical trial execution in a highly regulated environment.

What is the difference between Clinical Operations vs Clinical Research Associate?

AspectClinical OperationsClinical Research Associate
Required CredentialsBachelor's degree, experience in clinical trial managementBachelor's degree, often with certification in clinical research
Work EnvironmentProject management, coordinating multiple trial sitesMonitoring clinical sites, ensuring protocol compliance
Employer & Industry UsagePharmaceutical companies, CROs, biotech firmsResearch sites, CROs, pharmaceutical companies
Common Search & ComparisonFocuses on trial oversight and managementFocuses on site monitoring and data verification

Clinical Operations professionals oversee the planning, coordination, and management of clinical trials, ensuring they run smoothly across multiple sites. Clinical Research Associates primarily monitor clinical trial sites, verify data accuracy, and ensure compliance with protocols. While both roles require knowledge of clinical research, Clinical Operations has a broader scope involving project management, whereas CRAs focus on site-level monitoring.

What are the most commonly searched types of Clinical Operations jobs in California?

The most popular types of Clinical Operations jobs in California are:

What cities in California are hiring for Clinical Operations jobs?

Cities in California with the most Clinical Operations job openings:

Infographic showing various Clinical Operations job openings in California as of August 2026, with employment types broken down into 83% Full Time, 14% Part Time, 1% Temporary, 1% Contract, and 1% Nights. Highlights an 93% Physical, 3% Hybrid, and 4% Remote job distribution, with an average salary of $96,755 per year, or $46.5 per hour.

Clinical Operations Support

Orion Group

Orange, CA โ€ข On-site

$19 - $23.50/hr

Contractor

Posted 17 days ago


Key responsibilities

  • Support participant check-in, check-out, and scheduling for clinical research visits.

  • Prepare treatment rooms, study materials, and supplies prior to participant visits, and support inventory management.

  • Perform administrative tasks such as scheduling, documentation organization, data entry, and maintaining study records.


Job description

Clinical Operations Support II - Skincare
Location: Irvine, CA - 100% Onsite
Contract Duration: 12 Months, with potential for extension
Experience: 3-5 Years
Pay Rate: $19-$23.50/hr based on benefit selections
Position Overview
Orion Group is seeking a highly organized and personable Clinical Operations Support II professional to support a Skincare Clinical Research and Innovation Center in Irvine, CA.
This is a hands-on, onsite position combining clinical research, administrative support, participant coordination, medical office responsibilities, inventory management, and data entry. The ideal candidate will have excellent customer service skills, strong attention to detail, and prior experience working in a clinical research, medical office, healthcare, or similar patient-facing environment.
This individual will play an important role in supporting the day-to-day operation of clinical skincare studies and ensuring participants, study materials, treatment rooms, documentation, and supplies are prepared and organized.
Key Responsibilities
Participant & Clinical Study Support
  • Support participant check-in and check-out for clinical research visits.
  • Provide participants with required study forms and documentation for completion.
  • Schedule participant appointments and send appointment reminders.
  • Prepare patient charts, treatment rooms, study products, and supplies prior to scheduled visits.
  • Support participant compensation activities, including ordering compensation and providing eligible compensation upon study completion.
  • Maintain a professional and welcoming environment for study participants.
Administrative Support
  • Perform day-to-day administrative activities including scheduling, answering calls, responding to emails, and sending reminders.
  • Print, photocopy, scan, file, and organize clinical study documentation.
  • Support accurate and timely data entry activities.
  • Maintain organized electronic and physical study records.
  • Assist the clinical team with additional administrative and operational needs as required.
Clinical Environment & Inventory Support
  • Sanitize treatment rooms, instrumentation, and high-touch surfaces before and after participant visits and as needed.
  • Maintain skincare study product inventory and general clinical supplies.
  • Coordinate product and supply ordering, disposal, shipping, logging, tracking, and organization.
  • Assist with study product preparation.
  • Coordinate servicing and maintenance of clinical instrumentation as needed.
  • Ensure treatment rooms and clinical areas are organized and appropriately stocked.
Required Qualifications
  • Bachelor's degree preferred/required; an Associate's degree may be considered with relevant professional experience.
  • 3-5 years of relevant experience in clinical operations, clinical research support, medical office administration, healthcare, or a related environment.
  • Excellent customer service and interpersonal skills with the ability to interact professionally with study participants and internal teams.
  • Strong organizational skills and attention to detail.
  • Ability to prioritize multiple responsibilities and meet deadlines.
  • Ability to work independently while also collaborating effectively within a team.
  • Proficiency with Microsoft Word, Excel, PowerPoint, and Outlook.
  • Strong written and verbal communication skills.
Preferred Qualifications
  • Previous experience working in a medical office, clinical research site, dermatology practice, skincare setting, or other patient-facing healthcare environment.
  • Knowledge of the pharmaceutical, healthcare, or clinical research industry.
  • General knowledge of clinical research regulations and guidelines, including GCP, ICH, and applicable CFR requirements.
  • Experience supporting clinical documentation, patient scheduling, inventory management, or research data entry.
Ideal Candidate
The ideal candidate is someone who enjoys working directly with people while keeping the behind-the-scenes details organized. They should be comfortable moving between participant-facing responsibilities and administrative tasks throughout the day, whether preparing a treatment room, scheduling appointments, organizing study products, entering data, or ensuring clinical documentation is complete.
This position is best suited for a detail-oriented, dependable, and service-focused professional who thrives in an organized, hands-on clinical environment.
People are our business worldwide
Orion Group was founded in 1987 and is now one of the largest, independent, international recruitment companies. We have a network of 200 employees working from 24 offices, delivering a range of services - Talent Acquisition, Recruitment Outsourcing Services, Retained Search, Global Workforce Solutions, Completions & Commissioning and Materials Management - across 68 countries. As a global leader in workforce solutions, we recruit personnel across the Engineering & Technical, Office & Commercial, Scientific and Skilled Trades disciplines, for sectors including Oil & Gas, Life Science, Power & Utilities, Constructions & Infrastructure, Manufacturing and Renewables.