ZipRecruiter

Log In

1

Contract Clinical Operations Jobs in California (NOW HIRING)

OneLegacy

Contract Clinical Consultant

Azusa, CA · On-site

Available to work weekends and past their shift if needed to support operational needs. Work ... The Contract Clinical Consultant (LCSW/LMFT) provides advanced clinical expertise and field-based ...

OneLegacy

Contract Clinical Consultant

Azusa, CA · On-site

$52/hr

Available to work weekends and past their shift if needed to support operational needs. Work ... The Contract Clinical Consultant (LCSW/LMFT) provides advanced clinical expertise and field-based ...

Solomon Page

In-house Sr Clinical Research Associate

San Diego, CA · On-site

$60 - $75/hr

  • Medical

  • Dental

  • Vision

  • Retirement

... Contract Clinical Research Associate (CRA) to support ongoing clinical trials. This is an in-house clinical operations role (not a field monitoring position) with minimal travel required. * Pay rate ...

Neurocrine Biosciences

Director, Clinical Operations

San Diego, CA · On-site

$190.50 - $260/hr

  • Medical

  • Dental

  • Vision

  • Retirement

  • PTO

Manage relationships and expectations with CROs and other clinical contract service providers ... Manage operational activities of clinical programs with corporate partners * Perform additional ...

next page

Showing results 1-20

All JobsContract Clinical Operations JobsContract Clinical Operations Jobs in California

Contract Clinical Operations information

See California salary details

$34.5K

$96.8K

$184.1K

How much do contract clinical operations jobs pay per year?

As of Aug 19, 2026, the average yearly pay for contract clinical operations in California is $96,755.00, according to ZipRecruiter salary data. Most workers in this role earn between $71,600.00 and $112,000.00 per year, depending on experience, location, and employer.

What is contract clinical operations?

Contract Clinical Operations refer to the management and oversight of clinical trials and research activities that are conducted on a contractual basis, often by external vendors or contract research organizations (CROs). Professionals in this role ensure that clinical studies comply with regulatory requirements, timelines, and budgets while maintaining data integrity and participant safety. They coordinate tasks such as site selection, trial initiation, monitoring, and reporting, often acting as a liaison between sponsors and service providers. This role is essential for pharmaceutical, biotechnology, and medical device companies that outsource clinical research to meet project demands efficiently.

What are the key skills and qualifications needed to thrive in contract clinical operations?

To thrive in Contract Clinical Operations, you need expertise in clinical trial management, regulatory compliance, and contract negotiation, often backed by a degree in life sciences or a related field. Familiarity with clinical trial management systems (CTMS), electronic data capture (EDC) platforms, and knowledge of ICH-GCP guidelines are typically required. Strong organizational skills, attention to detail, and effective communication help professionals excel in managing multiple stakeholders and timelines. These capabilities ensure clinical studies are executed efficiently, ethically, and in accordance with regulatory standards.

What are some common challenges faced in a contract clinical operations role, and how can they be managed effectively?

Professionals in Contract Clinical Operations often encounter challenges such as coordinating multiple clinical trials across various sites, managing tight timelines, and ensuring strict regulatory compliance. Balancing the needs of sponsors, vendors, and cross-functional teams requires strong communication and organizational skills. Staying proactive, leveraging digital project management tools, and maintaining clear documentation can help address these challenges effectively. Collaborating closely with clinical research associates, data managers, and regulatory specialists is key to ensuring smooth trial execution and problem resolution.

What are the most commonly searched types of Clinical Operations jobs in California?

The most popular types of Clinical Operations jobs in California are:

What are popular job titles related to Contract Clinical Operations jobs in California?

For Contract Clinical Operations jobs in California, the most frequently searched job titles are:

What job categories do people searching Contract Clinical Operations jobs in California look for?

The top searched job categories for Contract Clinical Operations jobs in California are:

What cities in California are hiring for Contract Clinical Operations jobs?

Cities in California with the most Contract Clinical Operations job openings:

Contract Clinical Operations jobs near you
Infographic showing various Contract Clinical Operations job openings in California as of August 2026, with employment types broken down into 1% As Needed, 86% Full Time, 9% Part Time, 1% Temporary, 2% Contract, and 1% Nights. Highlights an 93% Physical, 3% Hybrid, and 4% Remote job distribution, with an average salary of $96,755 per year, or $46.5 per hour.

Clinical Trial Manager (contract)

ALX Oncology Inc.

South San Francisco, CA • On-site

$70/hr

Contractor

Posted yesterday

New

Job description

Reporting to the Executive Director, Clinical Operations, the contract Clinical Trial Manager (CTM) will manage the day-to-day operational execution of global clinical trials from study start-up through closeout. The contract CTM will be responsible for coordinating study activities, managing timelines and vendors, monitoring study and site performance, and working across functions to ensure study milestones and deliverables are achieved on time and to a high standard of quality.
This is a 6- to 12-month contract assignment offering approximately 40 hours per week. The anticipated pay rate is approximately $70 per hour for candidates in the San Francisco Bay Area. Candidates who can work onsite in South San Francisco on Mondays and Tuesdays as part of the company's hybrid work model will be given preference. ADC clinical trial experience strongly preferred.
Qualified contractors should have experience that includes:
  • Managing day-to-day global clinical trial activities from study start-up through conduct and closeout, including timelines, milestones, enrollment, and study performance.
  • Supporting protocol review, feasibility assessments, site selection and activation, and protocol amendment activities.
  • Managing CROs, sites, and clinical vendors, including oversight of plans, deliverables, timelines, budgets, and quality.
  • Overseeing monitoring activities, including monitoring report review, U.S. co-monitoring, site performance, protocol deviations, data queries, and follow-up of significant issues.
  • Identifying operational risks and working cross-functionally to develop and implement mitigation strategies.
  • Leading study team meetings and communicating study progress, risks, decisions, and action items to internal and external stakeholders.
  • Ensuring study conduct and TMF quality are consistent with study protocols, ICH/GCP, applicable regulatory requirements, and inspection-readiness expectations.
  • Clinical operations experience in biotechnology, pharmaceutical, or CRO environments; ADC clinical trial experience strongly preferred.
  • Strong project management, communication, problem-solving, and organizational skills; proficiency with EDC, IRT, CTMS, and eTMF.
  • Ability to work effectively in a small, fast-paced biotech environment.

About ALX Oncology
ALX Oncology (Nasdaq: ALXO) is a clinical-stage biotechnology company advancing a pipeline of novel therapies designed to treat cancer and extend patients' lives. ALX Oncology's lead therapeutic candidate, evorpacept, has demonstrated potential to serve as a cornerstone therapy upon which the future of immuno-oncology can be built. Evorpacept is currently being evaluated across multiple ongoing clinical trials in a wide range of cancer indications. ALX Oncology's second pipeline candidate, ALX2004, is a novel EGFR-targeted antibody-drug conjugate with a differentiated mechanism of action. A Phase 1, dose-escalation trial of ALX2004 is ongoing in patients with EGFR-expressing solid tumors. More information is available at www.alxoncology.com and on LinkedIn @ALX Oncology.

Apply