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Cell Line Development Jobs (NOW HIRING)

SystImmune, Inc

Senior Scientist, Cell Science

Redmond, WA · On-site

$90K - $140K/yr

Design and execute cell line development workflows, including vector design, transfection, clone screening, and selection for stable expression. * Perform cell culture experiments involving mammalian ...

Systimmune

Senior Scientist, Cell Science

Redmond, WA · On-site

$90K - $140K/yr

Design and execute cell line development workflows, including vector design, transfection, clone screening, and selection for stable expression. * Perform cell culture experiments involving mammalian ...

AbbVie

Senior Scientist I, Host Cell Engineering

Worcester, MA · On-site

$91K - $124K/yr

In addition, the successful candidate will enable the Biologics' pipeline through production cell line development and characterization and collaboration on cross-functional teams. Experience with ...

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How much do cell line development jobs pay per hour?

As of Jun 14, 2026, the average hourly pay for cell line development in the United States is $20.71, according to ZipRecruiter salary data. Most workers in this role earn between $17.31 and $21.88 per hour, depending on experience, location, and employer.

How much do cell biologists earn?

Cell biologists typically earn a median annual salary ranging from $50,000 to $90,000, depending on experience, education, and location. Salaries can increase with advanced skills, certifications, and work in biotech or pharmaceutical industries.

What is the highest paid type of scientist?

In the field of cell line development, senior scientists such as Principal Scientists or Directors typically earn the highest salaries, often exceeding $150,000 annually. These roles require extensive experience, advanced skills in bioprocessing and molecular biology, and often involve leadership responsibilities in biotech or pharmaceutical companies.

What are the key skills and qualifications needed to thrive in the Cell Line Development position, and why are they important?

To excel in Cell Line Development, a strong background in cell biology, molecular biology, and genetics is essential, often supported by a degree in a life science field. Experience with laboratory techniques such as cell culture, transfection, CRISPR gene editing, and using bioreactors or automated cell screening systems is highly valued. Attention to detail, problem-solving skills, and effective teamwork are important soft skills for success. These qualifications are crucial to consistently generate, characterize, and optimize stable cell lines for research or bioproduction purposes.

How much does a cell scientist make?

The average salary for a cell scientist or cell line development scientist typically ranges from $70,000 to $120,000 annually, depending on experience, education, and location. Entry-level positions may start lower, while experienced professionals with specialized skills or advanced degrees can earn higher salaries, especially in biotech or pharmaceutical industries.

What is a Cell Line Development job?

A Cell Line Development job involves creating and optimizing stable cell lines used in biopharmaceutical production, research, and drug development. Professionals in this role engineer cells to express desired proteins, ensuring high yield and stability for large-scale manufacturing. Responsibilities include transfection, selection, characterization, and process optimization. This work is critical for producing therapeutic proteins, monoclonal antibodies, and vaccines.

What does cell line development do?

Cell line development involves creating and optimizing cell lines used to produce biological products such as proteins or antibodies. It includes selecting, modifying, and maintaining cells in a laboratory setting, often using techniques like genetic engineering and cell culture to ensure consistent and high-yield production for research or manufacturing. This process is essential in biopharmaceutical development and requires skills in molecular biology and cell culture techniques.

What are typical day-to-day responsibilities for someone working in Cell Line Development?

Professionals in Cell Line Development typically spend their days culturing and maintaining mammalian or microbial cells, performing genetic modifications, and screening for desirable cell traits. They regularly design and execute experiments, analyze data, and meticulously document results to ensure reproducibility and regulatory compliance. Collaboration with upstream/downstream process teams, quality control, and research scientists is common, as is troubleshooting challenges such as cell viability or genetic stability. This role is hands-on and dynamic, offering a balance of bench work and data analysis throughout the week.

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What cities are hiring for Cell Line Development jobs? Cities with the most Cell Line Development job openings:
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Cell Line Development jobs near you
Infographic showing various Cell Line Development job openings in the United States as of June 2026, with employment types broken down into 1% Internship, 85% Full Time, and 14% Part Time. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $43,071 per year, or $20.7 per hour.
Senior Scientist, Cell Science

Senior Scientist, Cell Science

SystImmune, Inc

Redmond, WA • On-site

$90K - $140K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 16 days ago

Job description

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.
The Senior Scientist in the Cell Science Department is responsible for the development and optimization of CHO-based processes for the production of biotherapeutics. This role requires broad expertise and the ability to contribute to both drug discovery and development projects. A strong interest in bench work and hands-on experience with mammalian cell culture is essential.
This position requires a full-time onsite presence at our Redmond, WA location.
Responsibilities:
  • Design and execute cell line development workflows, including vector design, transfection, clone screening, and selection for stable expression.
  • Perform cell culture experiments involving mammalian cells (e.g., CHO cells) under sterile, aseptic conditions.
  • Develop and optimize expression systems, including promoters, selection markers, and gene amplification strategies for high-yield production.
  • Screen and characterize clones for productivity, stability, growth characteristics, and product quality attributes using molecular and biochemical assays.
  • Collaborate with project teams and downstream process development scientists to execute protocols, experimental plans, critical production batches, and technology transfers.
  • Manage and prioritize multiple projects while supporting and coordinating with other departments to advance company objectives and develop scalable, robust culture processes.
  • Write and review Standard Operating Procedures (SOPs) and technical reports for regulatory filings.
  • Prepare process transfer documents and cGMP documentation to support the successful implementation of process technologies in clinical and commercial manufacturing operations.
  • Collaborate with R&D and the manufacturing team in China, participating in meetings and providing technical support as needed.
  • Availability to work weekend and holiday shifts, as required.
  • Perform other duties as assigned.

Qualifications:
  • Ph.D. in Cell Biology or a related field, with 5+ years of relevant experience in the pharmaceutical or biotechnology industry.
  • Strong scientific background in recombinant protein expression, cell line development, cellular metabolism, and media optimization.
  • Experience in both early- and late-stage bioreactor operations, mammalian stable cell line development, and upstream process development is preferred.
  • Demonstrated expertise in advanced technologies for cell line development, with a focus on antibody production.
  • Strong knowledge of FDA regulations and other global health authority requirements related to Investigational New Drug (IND) applications, particularly those concerning single stable clone selection and characterization.
  • Excellent written, verbal, and interpersonal communication skills.
  • Proven ability to perform effectively under pressure, meet tight deadlines, and adapt to shifting project priorities and requirements.
  • Experience with high-throughput automated workstations for clone selection is highly desirable.
Compensation and Benefits:
The expected base salary range for this position is $90,000 - $140,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate's qualifications, experience, and skills.
While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.
SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.
We offer an opportunity for you to learn and grow while making significant contributions to the company's success.
SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.

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