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Cell Line Development Jobs in California (NOW HIRING)

Avid Bioservices

Cell Line Development

Tustin, CA

As a Cell Line Development Scientist , you will play a critical role in establishing high-performing mammalian cell lines that enable early-phase biologics programs. This position offers the ...

ATUM

Senior Director of Program Management

Newark, CA · On-site

$170K - $200K/yr

Senior Director of Program Management | ATUM ATUM is a leader in cell line development, gene synthesis, and protein engineering. We are seeking a strategic Director of Program Management to spearhead ...

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How much do cell line development jobs pay per hour?

As of Jun 14, 2026, the average hourly pay for cell line development in California is $20.44, according to ZipRecruiter salary data. Most workers in this role earn between $17.07 and $21.59 per hour, depending on experience, location, and employer.

How much do cell biologists earn?

Cell biologists typically earn a median annual salary ranging from $50,000 to $90,000, depending on experience, education, and location. Salaries can increase with advanced skills, certifications, and work in biotech or pharmaceutical industries.

What is the highest paid type of scientist?

In the field of cell line development, senior scientists such as Principal Scientists or Directors typically earn the highest salaries, often exceeding $150,000 annually. These roles require extensive experience, advanced skills in bioprocessing and molecular biology, and often involve leadership responsibilities in biotech or pharmaceutical companies.

What are the key skills and qualifications needed to thrive in the Cell Line Development position, and why are they important?

To excel in Cell Line Development, a strong background in cell biology, molecular biology, and genetics is essential, often supported by a degree in a life science field. Experience with laboratory techniques such as cell culture, transfection, CRISPR gene editing, and using bioreactors or automated cell screening systems is highly valued. Attention to detail, problem-solving skills, and effective teamwork are important soft skills for success. These qualifications are crucial to consistently generate, characterize, and optimize stable cell lines for research or bioproduction purposes.

How much does a cell scientist make?

The average salary for a cell scientist or cell line development scientist typically ranges from $70,000 to $120,000 annually, depending on experience, education, and location. Entry-level positions may start lower, while experienced professionals with specialized skills or advanced degrees can earn higher salaries, especially in biotech or pharmaceutical industries.

What is a Cell Line Development job?

A Cell Line Development job involves creating and optimizing stable cell lines used in biopharmaceutical production, research, and drug development. Professionals in this role engineer cells to express desired proteins, ensuring high yield and stability for large-scale manufacturing. Responsibilities include transfection, selection, characterization, and process optimization. This work is critical for producing therapeutic proteins, monoclonal antibodies, and vaccines.

What does cell line development do?

Cell line development involves creating and optimizing cell lines used to produce biological products such as proteins or antibodies. It includes selecting, modifying, and maintaining cells in a laboratory setting, often using techniques like genetic engineering and cell culture to ensure consistent and high-yield production for research or manufacturing. This process is essential in biopharmaceutical development and requires skills in molecular biology and cell culture techniques.

What are typical day-to-day responsibilities for someone working in Cell Line Development?

Professionals in Cell Line Development typically spend their days culturing and maintaining mammalian or microbial cells, performing genetic modifications, and screening for desirable cell traits. They regularly design and execute experiments, analyze data, and meticulously document results to ensure reproducibility and regulatory compliance. Collaboration with upstream/downstream process teams, quality control, and research scientists is common, as is troubleshooting challenges such as cell viability or genetic stability. This role is hands-on and dynamic, offering a balance of bench work and data analysis throughout the week.

What are the most commonly searched types of Cell Line Development jobs in California? The most popular types of Cell Line Development jobs in California are:
What cities in California are hiring for Cell Line Development jobs? Cities in California with the most Cell Line Development job openings:
Cell Line Development jobs near you
Infographic showing various Cell Line Development job openings in California as of June 2026, with employment types broken down into 1% Internship, 86% Full Time, and 13% Part Time. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $42,507 per year, or $20.4 per hour.
Cell Line Development

Cell Line Development

Avid Bioservices

Tustin, CA

Other

Posted 25 days ago

Job description

As a Cell Line Development Scientist, you will play a critical role in establishing high-performing mammalian cell lines that enable early-phase biologics programs. This position offers the opportunity to shape foundational capabilities in a fast-paced, collaborative environment focused on innovation and client success.

  • Design and execute strategies for stable cell line development using CHO cell line systems.
  • Perform hands-on CHO cell line development and characterization studies, including transfection, selection, single cell subcloning, growth and productivity screening, cell banking and stability assessment of cell banks.
  • Culture mammalian cells across multiple scales and formats, from 96-well plates up to large shake flasks, experience with ambr 250 and bioreactors is ideal.
  • Implement high-throughput screening and automation tools for clone evaluation.
  • Maintain rigorous documentation and ensure compliance with quality and regulatory standards.
  • Author and review cell line development reports, summaries, and presentations.
  • Present updates at client and cross-functional meetings.
  • Partner with Upstream and Downstream Process Development and Analytical teams to deliver integrated solutions.
  • Contribute to technology evaluations and continuous improvement initiatives for cell line workflows.

Minimum Qualifications:

  • M.S. in Cell Biology, Molecular Biology, Biochemistry, or related field.
  • 2-5 years of industry experience in cell development for biologics.
  • Hands-on experience with CHO cell systems, transfection methods, and clone screening for production of monoclonal antibodies, antibody-like molecules, enzymes, cytokines, bi-specifics and other recombinant molecules.
  • Strong knowledge of mammalian cell culture, molecular biology techniques and bio process engineering concepts.
  • Proficient in aseptic mammalian cell culture techniques.
  • Familiarity with automation platforms and data analysis tools.
  • Excellent problem-solving and communication skills.

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