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Cell Line Development Jobs in Boston, MA (NOW HIRING)

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Cell Line Development information

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$13

$22

$35

How much do cell line development jobs pay per hour?

As of Aug 5, 2026, the average hourly pay for cell line development in Boston, MA is $22.50, according to ZipRecruiter salary data. Most workers in this role earn between $18.80 and $23.75 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in cell line development?

To excel in Cell Line Development, a strong background in cell biology, molecular biology, and genetics is essential, often supported by a degree in a life science field. Experience with laboratory techniques such as cell culture, transfection, CRISPR gene editing, and using bioreactors or automated cell screening systems is highly valued. Attention to detail, problem-solving skills, and effective teamwork are important soft skills for success. These qualifications are crucial to consistently generate, characterize, and optimize stable cell lines for research or bioproduction purposes.

What is cell line development?

A Cell Line Development job involves creating and optimizing stable cell lines used in biopharmaceutical production, research, and drug development. Professionals in this role engineer cells to express desired proteins, ensuring high yield and stability for large-scale manufacturing. Responsibilities include transfection, selection, characterization, and process optimization. This work is critical for producing therapeutic proteins, monoclonal antibodies, and vaccines.

What are the typical day-to-day responsibilities in cell line development?

Professionals in Cell Line Development typically spend their days culturing and maintaining mammalian or microbial cells, performing genetic modifications, and screening for desirable cell traits. They regularly design and execute experiments, analyze data, and meticulously document results to ensure reproducibility and regulatory compliance. Collaboration with upstream/downstream process teams, quality control, and research scientists is common, as is troubleshooting challenges such as cell viability or genetic stability. This role is hands-on and dynamic, offering a balance of bench work and data analysis throughout the week.

What are the most commonly searched types of Cell Line Development jobs in Boston, MA? The most popular types of Cell Line Development jobs in Boston, MA are:
What cities near Boston, MA are hiring for Cell Line Development jobs? Cities near Boston, MA with the most Cell Line Development job openings:
Cell Line Development jobs near you
Infographic showing various Cell Line Development job openings in Boston, MA as of July 2026, with employment types broken down into 1% As Needed, 72% Full Time, 25% Part Time, and 2% Contract. Highlights an 93% Physical, 2% Hybrid, and 5% Remote job distribution, with an average salary of $46,792 per year, or $22.5 per hour.

Senior Scientist, Biologics Cell Line Development

Asimov, Inc

Boston, MA • On-site

$145K - $165K/yr

Full-time

Re-posted 27 days ago

Job description

Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform--from cells to software--to enable the design and manufacture of next-generation therapeutics.
We are seeking a Senior Scientist to join our Biologics Cell Line Development team in Boston, MA and help push the boundaries of biotherapeutic cell line development. This role is for a scientific innovator and a manager of junior scientists. The successful candidate will conduct & supervise CHO-based cell line development for biologic therapeutics moving into clinical development. Significant effort designing complex experimental approaches to improve expression systems and workflows through innovation and implementation of new technology is also an important part of this role.
The successful candidate will also work cross-functionally with Asimov's synthetic biology, modeling, process development and analytical teams. This is a unique opportunity to work at a nimble, forward-thinking synthetic biology startup and help build the future of biological engineering.
About the Role:
  • You'll perform CHO cell line development processes including transfection, cloning, characterization, and cell banking using state-of-the-art equipment.
  • You'll drive innovation through the development of improved genetic components, host cell line engineering and cell line development process optimization.
  • You'll identify emerging practices for biologics cell line development and manufacturing to shape scientific strategies and continued innovation.
  • You'll represent the cell line development team on cross-functional projects, making decisions for cell line activities and effectively communicating results, progress and plans.
  • You'll represent Asimov externally, contributing to industry conferences, industry forums, filing patents, and publishing peer-reviewed manuscripts.
  • You'll manage and mentor a team of 3+ scientists focused on CHO-based biologics CLD, providing technical direction and supporting them in their professional development.

About You:
  • 5+ years of experience in CHO-based cell line development is a must, stemming from expressing IgGs and bispecifics in an industrial CLD environment.
  • You have a Ph.D. in Biological Engineering, Cell Biology, Molecular Biology, or a related field.
  • You're a creative problem solver never satisfied with the status quo and get excited about the opportunity to drive the creation of disruptive technology.
  • Minimum 1 year experience managing direct report(s) and providing technical guidance.
  • Don't let this stop you from applying, but it's a plus if you are familiar with any of the following: vector optimization to improve titer and product quality attributes for complex bispecific scaffolds; CLD process optimization; or development of automated high-throughput screening for CLD workflows.
  • Experience working with a global customer base isn't a requirement for this role but bonus points if you have it.

We're fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.

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