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Cell Line Development Jobs in Boston, MA (NOW HIRING)

Design, execute and analyze platform research studies to support process development activities which aim to reduce overall timelines while improving cell line productivity and product quality ...

Validate newly developed assays by analyzing experimental results, troubleshooting issues, and ... Experience in Tissue Culture including cell line maintenance, treatments, and lysis etc.

Senior scientist - biology

Natick, MA · On-site

$94K - $129K/yr

... development. The successful candidate will work with limited supervision as part of a highly ... cell line generation * Experience with cell-based assays such as Cell titer glow, Caspase Glo ...

Validate newly developed assays by analyzing experimental results, troubleshooting issues, and ... Experience in Tissue Culture including cell line maintenance, treatments, and lysis etc.

Research Assistant III

Cambridge, MA · Hybrid

$21.25 - $29.25/hr

... human development. The majority of their time is spent coordinating multiple aspects of the labs ... Cell printing, optimizing differentiation protocols optimized for each line, performing and ...

Research Assistant III

Cambridge, MA · On-site

$21.25 - $29.25/hr

... human development. The majority of their time is spent coordinating multiple aspects of the labs ... Cell printing, optimizing differentiation protocols optimized for each line, performing and ...

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Cell Line Development information

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$13

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How much do cell line development jobs pay per hour?

As of Jun 17, 2026, the average hourly pay for cell line development in Boston, MA is $22.50, according to ZipRecruiter salary data. Most workers in this role earn between $18.80 and $23.75 per hour, depending on experience, location, and employer.

How much do cell biologists earn?

Cell biologists typically earn a median annual salary ranging from $50,000 to $90,000, depending on experience, education, and location. Salaries can increase with advanced skills, certifications, and work in biotech or pharmaceutical industries.

What is the highest paid type of scientist?

In the field of cell line development, senior scientists such as Principal Scientists or Directors typically earn the highest salaries, often exceeding $150,000 annually. These roles require extensive experience, advanced skills in bioprocessing and molecular biology, and often involve leadership responsibilities in biotech or pharmaceutical companies.

What are the key skills and qualifications needed to thrive in the Cell Line Development position, and why are they important?

To excel in Cell Line Development, a strong background in cell biology, molecular biology, and genetics is essential, often supported by a degree in a life science field. Experience with laboratory techniques such as cell culture, transfection, CRISPR gene editing, and using bioreactors or automated cell screening systems is highly valued. Attention to detail, problem-solving skills, and effective teamwork are important soft skills for success. These qualifications are crucial to consistently generate, characterize, and optimize stable cell lines for research or bioproduction purposes.

How much does a cell scientist make?

The average salary for a cell scientist or cell line development scientist typically ranges from $70,000 to $120,000 annually, depending on experience, education, and location. Entry-level positions may start lower, while experienced professionals with specialized skills or advanced degrees can earn higher salaries, especially in biotech or pharmaceutical industries.

What is a Cell Line Development job?

A Cell Line Development job involves creating and optimizing stable cell lines used in biopharmaceutical production, research, and drug development. Professionals in this role engineer cells to express desired proteins, ensuring high yield and stability for large-scale manufacturing. Responsibilities include transfection, selection, characterization, and process optimization. This work is critical for producing therapeutic proteins, monoclonal antibodies, and vaccines.

What does cell line development do?

Cell line development involves creating and optimizing cell lines used to produce biological products such as proteins or antibodies. It includes selecting, modifying, and maintaining cells in a laboratory setting, often using techniques like genetic engineering and cell culture to ensure consistent and high-yield production for research or manufacturing. This process is essential in biopharmaceutical development and requires skills in molecular biology and cell culture techniques.

What are typical day-to-day responsibilities for someone working in Cell Line Development?

Professionals in Cell Line Development typically spend their days culturing and maintaining mammalian or microbial cells, performing genetic modifications, and screening for desirable cell traits. They regularly design and execute experiments, analyze data, and meticulously document results to ensure reproducibility and regulatory compliance. Collaboration with upstream/downstream process teams, quality control, and research scientists is common, as is troubleshooting challenges such as cell viability or genetic stability. This role is hands-on and dynamic, offering a balance of bench work and data analysis throughout the week.

What are the most commonly searched types of Cell Line Development jobs in Boston, MA? The most popular types of Cell Line Development jobs in Boston, MA are:
What cities near Boston, MA are hiring for Cell Line Development jobs? Cities near Boston, MA with the most Cell Line Development job openings:
Infographic showing various Cell Line Development job openings in Boston, MA as of June 2026, with employment types broken down into 1% Internship, 84% Full Time, and 15% Part Time. Highlights an 94% Physical, 1% Hybrid, and 5% Remote job distribution, with an average salary of $46,792 per year, or $22.5 per hour.
Clinical Lab Process Development Associate I- Cell Factory

Clinical Lab Process Development Associate I- Cell Factory

Broad Institute

Burlington, MA • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 29 days ago


Job description

General information
Location
Burlington, MA
Ref #
43480
Job Family
Research
Workplace
On-Site
Date published
06/14/2026
Time Type
Full time
Pay Range
58,000 - 76,667 Usd Annual
Description & Requirements
The Genomics Platform is dedicated to solving the world's most challenging biomedical problems through the continuous development and investment in cutting edge technology and large-scale research projects that are both challenging and complex.
In support of continually changing initiatives, the Clinical Laboratory Process Development Associate I is committed to carrying out innovative, high-throughput lab processes and supporting the highest quality research to understand the impacts of genetic regulation on human health and disease. In this role, you are responsible for processing samples through a high throughput clinical research laboratory and meeting production goals.
In this position, you will complete multi-step processes for cell expansion, banking, perturbations, screens and working to develop cellular models of disease and biological processes of interest to researchers. In addition to standard production processes, this position will require individuals to participate in continuous improvement solutions through appropriate change management procedures and troubleshooting processes as needed.
The individual may be involved with the designing and executing of development, process improvement, or troubleshooting projects under direct guidance from the supervisor in support of platform goals and may be required to complete related training in JMP, Six Sigma, or other process improvement methods. Upon completion of these projects the individual is responsible for documenting and communicating results to others in the Platform during dedicated meetings. In addition, PDAs will assist with the general supervision of work of other laboratory personnel such as Process Development Technicians and Accessioning Technicians as required.
Job Responsibilities:
  • Maintain and optimize mammalian cell culture systems for screening experiments.
  • Apply functional genomics techniques, including epigenomics, single-cell, transcriptomics, and CRISPR-based assays in human cells and tissues
  • Follow standard operating procedures
  • Each individual performs only those high complexity tests that are authorized by the Laboratory Director and require a degree of skill commensurate with the individual's education, training, experience, and technical abilities.
  • Tests will require the exercise of independent judgment and responsibility with minimal supervisor by the laboratory director or supervisor
  • Adhere to the laboratory's quality control policies, document all quality control activities, instrument and procedural calibrations and maintenance performed.
  • Follow the laboratory's established policies and procedures whenever test systems are not within the laboratory's established acceptable levels of performance.
  • Be capable of identifying problems that may adversely affect test performance or reporting of test results. Correct the problems according to procedures or immediately notify the General Supervisor, Technical Supervisor, Clinical Consultant or Laboratory Director.
  • Document all corrective actions taken when test systems deviate from the laboratory's established performance specifications.
  • Review and monitor quality metrics and communicate results to others in the Platform during dedicated meetings as needed.

Minimum requirements:
  • BS/BA degree in Biology or Chemistry.
  • 1+ years of relevant full time laboratory experience in this specialty subsequent to obtaining B.S./B.A. degree is required.
    • Working, solid knowledge of basic aseptic / mammalian cell culture laboratory techniques required as a part of the above 1 year of experience.
  • Strong analytical skills, problem solving ability, and innovation aptitude required.
  • Recent (within the last year) laboratory experience with the use of standard cell lab equipment such as pipettes, centrifuges, biosafety cabinets, microscopes, gel electrophoresis required.
  • Knowledge of high-throughput screening and automation and/or experience working in a high throughput production setting is desired, but not required
  • Experience with genome editing tools including CRISPR targeting in various human cell types is preferred.
  • Strong hands-on experience in molecular biology, genomics, and cellular biology (cell-based assays) is preferred.
  • Familiarity with single cell sequencing methods preferred.
  • Experience with iPSCs, cell line and/or primary cell culture preferred.

*Please attach your resume and a copy of your transcripts when applying to be considered.**
The Broad Institute will not offer visa sponsorship for this opportunity.
The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law.
At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.
The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.
Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.