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Cell Line Development Jobs in Gaithersburg, MD (NOW HIRING)

Precigen, Inc

Manager, Quality Control

Germantown, MD · On-site

$105K - $140K/yr

Training, coaching, and development of QC staff * Develop, revise, and review SOPs, qualification ... Perform review of QC documentation (equipment logbooks, sol'n prep record, cell line records, TRF ...

WorqStrap

Bioassay Research Scientist II

Silver Spring, MD · On-site

$65 - $108/hr

... development for biological products whose mechanisms of action depend on modulation of specific subunits.**What You Will Do****:*** Perform mammalian cell culture, cell line engineering support, and ...

Guidehouse

Scientist

Gaithersburg, MD · On-site

$74K - $124K/yr

Hands-on experience with multiple supporting technologies for cell line engineering such as cell ... Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities * Employee ...

Guidehouse

Scientist

Gaithersburg, MD · On-site

$74K - $124K/yr

Hands-on experience with multiple supporting technologies for cell line engineering such as cell ... Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities * Employee ...

Umd

Assistant Research Professor

College Park, MD · On-site

$110K - $130K/yr

The biomanufacturing testbed facility is underpinned by a newly developed NIST reference material (RM), so called NISTCHO. NISTCHO is a CHO cell line expressing the amino acid sequences of the ...

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Cell Line Development information

See Gaithersburg, MD salary details

$13

$22

$35

How much do cell line development jobs pay per hour?

As of Aug 26, 2026, the average hourly pay for cell line development in Gaithersburg, MD is $22.37, according to ZipRecruiter salary data. Most workers in this role earn between $18.70 and $23.65 per hour, depending on experience, location, and employer.

What is cell line development?

A Cell Line Development job involves creating and optimizing stable cell lines used in biopharmaceutical production, research, and drug development. Professionals in this role engineer cells to express desired proteins, ensuring high yield and stability for large-scale manufacturing. Responsibilities include transfection, selection, characterization, and process optimization. This work is critical for producing therapeutic proteins, monoclonal antibodies, and vaccines.

What are the typical day-to-day responsibilities in cell line development?

Professionals in Cell Line Development typically spend their days culturing and maintaining mammalian or microbial cells, performing genetic modifications, and screening for desirable cell traits. They regularly design and execute experiments, analyze data, and meticulously document results to ensure reproducibility and regulatory compliance. Collaboration with upstream/downstream process teams, quality control, and research scientists is common, as is troubleshooting challenges such as cell viability or genetic stability. This role is hands-on and dynamic, offering a balance of bench work and data analysis throughout the week.

What are the key skills and qualifications needed to thrive in cell line development?

To excel in Cell Line Development, a strong background in cell biology, molecular biology, and genetics is essential, often supported by a degree in a life science field. Experience with laboratory techniques such as cell culture, transfection, CRISPR gene editing, and using bioreactors or automated cell screening systems is highly valued. Attention to detail, problem-solving skills, and effective teamwork are important soft skills for success. These qualifications are crucial to consistently generate, characterize, and optimize stable cell lines for research or bioproduction purposes.

Cell Line Development jobs near you
Infographic showing various Cell Line Development job openings in Gaithersburg, MD as of August 2026, with employment types broken down into 1% As Needed, 81% Full Time, 16% Part Time, and 2% Contract. Highlights an 86% Physical, 2% Hybrid, and 12% Remote job distribution, with an average salary of $46,536 per year, or $22.4 per hour.

Senior Scientist, Bioproduction and Bioprocessing

Join Our Team

Rockville, MD • On-site

$93K - $127K/yr

Full-time

Medical, Dental, Vision, Life

Posted 17 days ago

Job description

Description:

The Senior Scientist, Bioproduction & Bioprocessing is responsible for leading the development, optimization, and execution of mammalian cell-based protein production workflows to support organizational research, development, and manufacturing needs. This role provides subject-matter expertise in cell line development, transient expression, and upstream bioprocessing, and ensures high-quality delivery of materials through collaboration with cross-functional teams. The Senior Scientist contributes to scientific innovation, process improvement, and customer support activities.

  • Lead and execute workflows for stable pool and stable cell line generation, including transfection, clone screening, productivity assessment, and documentation.
  • Perform stable pool and transient experiments using CHOZN, CHOK1-sv, CHOK, HEK293, and other protein production-relevant cell lines.
  • Develop, optimize, and scale transient protein expression processes for antibodies and recombinant proteins.
  • Conduct upstream protein expression studies, including small-scale evaluations and preparation for scale-up.
  • Design, perform, and troubleshoot laboratory experiments in accordance with established protocols, quality standards, and regulatory expectations.
  • Analyze experimental data, prepare technical summaries, and present results to internal and external stakeholders.
  • Collaborate with downstream purification, analytical development, and project management teams to ensure alignment and timely delivery of materials.
  • Provide scientific support to customer-facing teams, including remote and onsite troubleshooting with Field Application Scientists.
  • Identify opportunities to enhance bioproduction workflows, including media/feed optimization, vector improvements, and process parameter refinement.
  • Evaluate and implement new technologies, automation tools, and high-throughput approaches to increase efficiency and scalability.
  • Lead exploratory studies to assess emerging bioprocessing methods and integrate validated improvements into standard workflows.
  • Contribute to internal innovation initiatives, including development of new production strategies, platform enhancements, and scientific capability expansion.
  • Provide technical insight to support long-term bioproduction strategy and organizational growth.
  • Maintain accurate, complete, and compliant laboratory records.
  • Ensure adherence to organizational, regulatory, and safety standards.
Requirements:
  • PhD in biological sciences or related field with 10+ years of relevant industry experience (or Master’s degree with 13+ years of experience) in bioproduction, bioprocessing, or cell line development
  • Demonstrated expertise in stable cell line development and clone selection.
  • Extensive hands-on experience with transient expression of antibodies or recombinant proteins.
  • Strong foundation in mammalian cell culture and upstream protein expression.
  • Experience with high-throughput screening, automation, or advanced analytical tools.
  • Background in cell engineering, vector design, media/feed optimization, or bioprocess development.
  • Prior experience in structured, milestone-driven industry or core laboratory environments.
  • Good communication skills and ability to work collaboratively with internal team members and customers
  • Ability to travel up to 20%


MaxCyte offers a base salary, annual bonus, and equity. MaxCyte also offers a comprehensive benefits package including health, dental, vision, life, and disability insurance and generous time off.


MaxCyte is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or other legally protected status

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