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$29K

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How much do cell line development associate jobs pay per year?

As of Sep 15, 2026, the average yearly pay for cell line development associate in the United States is $53,418.00, according to ZipRecruiter salary data. Most workers in this role earn between $42,500.00 and $60,000.00 per year, depending on experience, location, and employer.

What does a cell line development associate do?

A Cell Line Development Associate is responsible for generating and characterizing cell lines used in research or biomanufacturing, particularly for producing therapeutic proteins or biologics. They perform tasks such as transfecting cells, selecting stable clones, expanding cultures, and analyzing cell growth and productivity. Their work ensures the creation of robust, high-quality cell lines that meet regulatory and production standards. This role is crucial in pharmaceutical, biotechnology, and research settings.

What are some common challenges faced by cell line development associates during cell line generation projects?

Cell Line Development Associates often encounter challenges such as ensuring the stability and productivity of cloned cell lines, troubleshooting low expression levels, and minimizing contamination risks. Managing tight project timelines while maintaining rigorous documentation and quality standards can also be demanding. Additionally, adapting to evolving technology platforms and collaborating effectively with upstream and downstream teams are key aspects of the role. Overcoming these obstacles requires strong problem-solving skills, attention to detail, and effective communication within multidisciplinary project groups.

What are the key skills and qualifications needed to thrive as a cell line development associate, and why are they important?

To thrive as a Cell Line Development Associate, you need a background in cell biology, molecular biology, or related fields, typically supported by a bachelor's or master's degree in life sciences. Familiarity with cell culture techniques, gene editing tools (like CRISPR), and laboratory information management systems (LIMS) is important. Attention to detail, strong problem-solving abilities, and effective teamwork set exceptional candidates apart. These competencies ensure robust, high-quality cell line generation critical for research and bioproduction success.

What is the difference between Cell Line Development Associate vs Research Associate?

AspectCell Line Development AssociateResearch Associate
Required CredentialsBachelor's degree in biology, biotechnology, or related field; laboratory skillsBachelor's or master's degree in a scientific discipline; laboratory experience
Work EnvironmentBiotech or pharmaceutical labs focused on cell line creation and developmentResearch labs across various scientific fields, including biology and chemistry
Employer & Industry UsageBiotech companies, pharmaceutical firms, contract research organizationsUniversities, research institutes, biotech and pharma companies

The main difference is that a Cell Line Development Associate specializes in creating and optimizing cell lines for bioproduction, while a Research Associate may work on broader research projects across multiple scientific areas. Both roles require laboratory skills and relevant degrees, but the Cell Line Development Associate focuses specifically on cell line processes within biotech and pharma industries.

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Cell Line Development Associate jobs near you

Cell Line Development Scientist

Oklahoma City, OK • On-site

Wheeler Bio, Inc.
Biotechnology Research and Development • 11 - 50 employees
Learn more about Wheeler Bio, Inc.external

Full-time

Posted 10 days ago

Job description

Job Title: Cell Line Development Scientist
Location: Oklahoma City, OK
Department: Process Development
Job Type: Full-Time

Position Summary:

As a Cell Line Development Scientist, you will support the development, optimization, and creation of mammalian cell lines for the manufacture of biologic drug substances. You will contribute to the design and execution of laboratory experiments, data analysis, and technical documentation.

Key Responsibilities:

·                     Perform laboratory experiments to support mammalian cell line development and upstream process development.

·                     Utilize Design of Experiments (DoE) for data analysis and experimental design.

·                     Coordinate and execute all phases of the CLD process, collaborating with downstream, analytical and formulation teams.

·                     Work cross-functionally with analytical development, MSAT, manufacturing and quality teams to drive successful technology transfer.

·                     Translate client amino acid sequences into nucleotide FASTA files to expedite DNA ordering process.

·                     Prepare buffers, media, and other solutions according to SOPs and protocols.

·                     Operate and maintain cell line development equipment including electroporation, single cell dispensing, and imaging equipment.

·                     Program and operate ambr250 microbioreactor system.

·                     Collect, analyze, and interpret experimental data; maintain accurate lab records and electronic notebooks.

·                     Present findings in internal and client meetings.

·                     Author technical reports and regulatory documentation.

·                     Complete Root Cause Analyses as needed, implementing corrective and preventative actions as needed.

·                     Mentor junior scientists and research associates in daily activities, data trending and data analysis.

·                     Follow all safety, quality, and compliance requirements.

Qualifications:

Education:

·                     Bachelor's, Master's or PhD degree in Chemical Engineering, Biochemistry, Biotechnology, Biology, or related field.

Experience:

·                     4 - 8 years of hands-on experience in a bioprocessing or biopharmaceutical development environment (academic or industrial); some education qualifications may substitute for some years of experience.

·                     4 - 8 years of experience with mammalian stable cell line generation is required.

·                     Familiarity with transposon-based expression systems is a plus.

·                     Experience in a CDMO environment is preferred.

·                     Knowledge of protein purification and analytical techniques is a plus.

Skills and Knowledge:

·                     Understanding of cGMP, GLP, or other regulatory standards is preferred.

·                     Strong analytical and problem-solving skills.

·                     Good written and verbal communication skills.

·                     Ability to work both independently and in a collaborative team environment.

Physical Requirements:

·         Ability to perform lab-based tasks, including standing for long periods, working with various laboratory equipment, and handling biological samples.

·         Must be able to lift and carry equipment, reagents, and materials weighing up to 25 pounds.

Working Conditions:

  • This position requires flexibility in working hours, including potential shift work, weekends, on-call duties and holidays as necessary.
  • Work involves the handling of biological materials.