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Cell Line Development Jobs in Philadelphia, PA (NOW HIRING)

Legend Biotech US

Scientist

Philadelphia, PA

... cell line optimization. * Perform media optimization, feeding strategy development, and process control adjustments to improve yield, quality, scalability and robustness. * Develop and execute fit ...

Legend Biotech US

Scientist

Philadelphia, PA · On-site

Strong technical background in molecular biology techniques, including plasmid construction, PCR/qPCR/dPCR based assay, and cell line development. * Demonstrated ability to design, execute, analyze ...

Pioneer Data

LCMS Scientist

Spring House, PA · On-site

Overview Be a part of a team developing state-of-the-art automation systems for mass spectrometry applied to biotherapeutics cell line development. This role will leverage and develop the next phase ...

CarVision Inc.

Data Entry Specialist

Norristown, PA · On-site

$16.25 - $21.75/hr

Free Cell Line for every associate * Paid Vacation * Paid Company Holidays * Paid Training * Ongoing Professional Development * Employee Discounts * Family-Friendly and Inclusive Culture * Career ...

CarVision Inc.

Data Entry Specialist

Norristown, PA

$16.25 - $21.75/hr

Free Cell Line for every associate * Paid Vacation * Paid Company Holidays * Paid Training * Ongoing Professional Development * Employee Discounts * Family-Friendly and Inclusive Culture * Career ...

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Cell Line Development information

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How much do cell line development jobs pay per hour?

As of Aug 26, 2026, the average hourly pay for cell line development in Philadelphia, PA is $20.90, according to ZipRecruiter salary data. Most workers in this role earn between $17.45 and $22.07 per hour, depending on experience, location, and employer.

What is cell line development?

A Cell Line Development job involves creating and optimizing stable cell lines used in biopharmaceutical production, research, and drug development. Professionals in this role engineer cells to express desired proteins, ensuring high yield and stability for large-scale manufacturing. Responsibilities include transfection, selection, characterization, and process optimization. This work is critical for producing therapeutic proteins, monoclonal antibodies, and vaccines.

What are the typical day-to-day responsibilities in cell line development?

Professionals in Cell Line Development typically spend their days culturing and maintaining mammalian or microbial cells, performing genetic modifications, and screening for desirable cell traits. They regularly design and execute experiments, analyze data, and meticulously document results to ensure reproducibility and regulatory compliance. Collaboration with upstream/downstream process teams, quality control, and research scientists is common, as is troubleshooting challenges such as cell viability or genetic stability. This role is hands-on and dynamic, offering a balance of bench work and data analysis throughout the week.

What are the key skills and qualifications needed to thrive in cell line development?

To excel in Cell Line Development, a strong background in cell biology, molecular biology, and genetics is essential, often supported by a degree in a life science field. Experience with laboratory techniques such as cell culture, transfection, CRISPR gene editing, and using bioreactors or automated cell screening systems is highly valued. Attention to detail, problem-solving skills, and effective teamwork are important soft skills for success. These qualifications are crucial to consistently generate, characterize, and optimize stable cell lines for research or bioproduction purposes.

Cell Line Development jobs near you
Infographic showing various Cell Line Development job openings in Philadelphia, PA as of August 2026, with employment types broken down into 1% As Needed, 81% Full Time, 15% Part Time, and 3% Contract. Highlights an 91% Physical, 3% Hybrid, and 6% Remote job distribution, with an average salary of $43,462 per year, or $20.9 per hour.

Scientist - Cell Line Development

Wilmington, DE

Thermo Fisher Scientific
Biotechnology Research and Development • 10K+ employees

7.8

Company rating: 7.8 out of 10

Based on 428 frontline employees who took The Breakroom Quiz

174th of 544 rated manufacturers

People enjoy working here

Good employer

Recommended by students

Learn more about Thermo Fisher Scientificexternal

Full-time

Posted 8 days ago

Job description

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Office

Job Description

Thermo Fisher's clinical research business is a leading global contract research organization and world leader in serving science. We are passionate, deliberate, and driven by our mission – to enable our clients to make the world healthier, safer, and cleaner.
 

Within our Analytical Services team, we have a functional service provider solution, which is an outstanding partnership that allows our customers to use the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits.
The cell culture scientist will conduct the cell culture lab works in both cell line development (CLD) and cell culture process development (Upstream) teams to support the development of stable manufacture cell lines that express the therapeutic antibodies.

Essential Functions:

  • Executes routine cell culture experiments to support CLD and Upstream teams, include sampling, counting and passaging cells, preparation DNA for transfection, conduct experiment in transfection, screening of transfected cells.

  • Prepare media, buffers and solutions needed for laboratory work.

  • Write routine electronic laboratory notebook (ELN).

  • Present work summary to internal function teams.

  • Communicates clearly and collaborate actively with internal cross-functional teams to facilitate pipeline development of large molecules.

  • Other responsibilities as assigned

Education and Experience:

  • Bachelor's degree or equivalent in relevant life sciences program

  • AND 2+ years of experience OR MS degree in relevant scientific degree

  • Preferred: Experience with cell culture process development

In some cases an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.
 

Knowledge, Skills and Abilities:

  • Knowledge of applicable regulatory authority, compendia and ICH guidelines

  • Ability to understand and independently apply GMPs and /or GLPs to everyday work with regard to documentation and instrument use

  • Ability to utilize Microsoft Excel and Word to perform tasks

  • Ability to independently optimize analytical methods

  • Good written and oral communication skills

  • Time management and project management skills

  • Problem solving and troubleshooting abilities

  • Ability to work in a collaborative work environment with a team


Thermo Fisher Scientific values the health and wellbeing of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive.  Below is listed the working environment/requirements for this role:

  • Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.

  • Able to work upright and stationary and/or standing for typical working hours.

  • Able to lift and move objects up to 25 pounds.

  • Able to work in non-traditional work environments.

  • Able to use and learn standard office equipment and technology with proficiency.

  • May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.

  • Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.  
     

Our 4i Values:
 

Integrity – Innovation – Intensity – Involvement
 

If you resonate with our 4i values above, and ultimately wish to accelerate the delivery of safe and effective therapeutics for some of the world’s most urgent health needs, submit your application – we’d love to hear from you!

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